Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Konstantinos, Mengrelis"'
Autor:
Moritz Muckenhuber, Konstantinos Mengrelis, Anna Marianne Weijler, Romy Steiner, Verena Kainz, Marlena Buresch, Heinz Regele, Sophia Derdak, Anna Kubetz, Thomas Wekerle
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The efficacy of costimulation blockade with CTLA4-Ig (belatacept) in transplantation is limited due to T cell-mediated rejection, which also persists after induction with anti-thymocyte globulin (ATG). Here, we investigate why ATG fails to p
Externí odkaz:
https://doaj.org/article/7a33667422cf46129bf79b0e8be234ff
Autor:
Lisa Prickler, Ulrike Baranyi, Konstantinos Mengrelis, Anna Marianne Weijler, Verena Kainz, Bernhard Kratzer, Romy Steiner, Jasmin Mucha, Elisa Rudoph, Nina Pilat, Barbara Bohle, Herbert Strobl, Winfried Franz Pickl, Rudolf Valenta, Birgit Linhart, Thomas Wekerle
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionProphylactic strategies to prevent the development of allergies by establishing tolerance remain an unmet medical need. We previously reported that the transfer of autologous hematopoietic stem cells (HSC) expressing the major timothy gra
Externí odkaz:
https://doaj.org/article/a785c8ea646145588ea6e987232eb280
Autor:
Konstantinos Mengrelis, Gerhard Niederacher, Lisa Prickler, Verena Kainz, Anna Marianne Weijler, Elisa Rudolph, Victoria Stanek, Julia Eckl-Dorna, Ulrike Baranyi, Andreas Spittler, Margarete Focke-Tejkl, Barbara Bohle, Rudolf Valenta, Christian Friedrich Wilhelm Becker, Thomas Wekerle, Birgit Linhart
Publikováno v:
Cells, Vol 13, Iss 5, p 446 (2024)
Up to a third of the world’s population suffers from allergies, yet the effectiveness of available preventative measures remains, at large, poor. Consequently, the development of successful prophylactic strategies for the induction of tolerance aga
Externí odkaz:
https://doaj.org/article/5b2c75a3f90f478a97d0a521408b732b
Autor:
Moritz Muckenhuber, Jasmin Mucha, Konstantinos Mengrelis, Christopher How, Roman Reindl-Schwaighofer, Andreas Heinzel, Verena Kainz, Nina Worel, Gabriela Berlakovich, Matthias Edinger, Rainer Oberbauer, Thomas Wekerle
Publikováno v:
American Journal of Transplantation. 23:84-92
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50587b6f9cda80d0bfe4a4d70bfcc350
https://doi.org/10.1016/j.ajt.2022.09.002
https://doi.org/10.1016/j.ajt.2022.09.002
Autor:
Konstantinos Mengrelis, Ching-In Lau, Jasmine Rowell, Anisha Solanki, Sonia Norris, Susan Ross, Masahiro Ono, Susan Outram, Tessa Crompton
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Here we investigate the function of Hedgehog (Hh) signaling in thymic γδ T-cell maturation and subset differentiation. Analysis of Hh mutants showed that Hh signaling promotes γδ T-cell development in the thymus and influences γδ T-cell effecto
Externí odkaz:
https://doaj.org/article/4328ac17533e4de091c065c06209e14a
Publikováno v:
Transplantation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc4ecfda19d9e8d222ee056eae367497
https://doi.org/10.1097/tp.0000000000004589
https://doi.org/10.1097/tp.0000000000004589
Autor:
Alessandro Barbarulo, Ching-In Lau, Konstantinos Mengrelis, Susan Ross, Anisha Solanki, José Ignacio Saldaña, Tessa Crompton
Publikováno v:
Journal of Developmental Biology, Vol 4, Iss 3, p 22 (2016)
T cells develop in the thymus, which provides an essential environment for T cell fate specification, and for the differentiation of multipotent progenitor cells into major histocompatibility complex (MHC)-restricted, non-autoreactive T cells. Here w
Externí odkaz:
https://doaj.org/article/58d27381842e4da681b6a1ac26fd7260
Autor:
Michael Burch, E. Graham Davies, Dietmar Pils, Kimberly Gilmour, Eleanor Watt, Ching-In Lau, Stuart Adams, Filip Kucera, Nadia Shahid, Tessa Crompton, Susan Ross, Konstantinos Mengrelis
Publikováno v:
Pediatric Transplantation. 25
Paediatric heart transplantation recipients suffer an increased incidence of infectious, autoimmune and allergic problems. The relative roles of thymus excision and immunosuppressive treatments in contributing to these sequelae are not clear. We comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4f73dfc9b20737458ba9ea2d2aae658
https://doi.org/10.1111/petr.13930
https://doi.org/10.1111/petr.13930
Autor:
E Graham, Davies, Melissa, Cheung, Kimberly, Gilmour, Jesmeen, Maimaris, Joe, Curry, Anna, Furmanski, Neil, Sebire, Neil, Halliday, Konstantinos, Mengrelis, Stuart, Adams, Jolanta, Bernatoniene, Ronald, Bremner, Michael, Browning, Blythe, Devlin, Hans Christian, Erichsen, H Bobby, Gaspar, Lizzie, Hutchison, Winnie, Ip, Marianne, Ifversen, T Ronan, Leahy, Elizabeth, McCarthy, Despina, Moshous, Kim, Neuling, Malgorzata, Pac, Alina, Papadopol, Kathryn L, Parsley, Luigi, Poliani, Ida, Ricciardelli, David M, Sansom, Tiia, Voor, Austen, Worth, Tessa, Crompton, M Louise, Markert, Adrian J, Thrasher
Publikováno v:
Journal of Allergy and Clinical Immunology
The Journal of Allergy and Clinical Immunology
The Journal of Allergy and Clinical Immunology
Background Thymus transplantation is a promising strategy for the treatment of athymic complete DiGeorge syndrome (cDGS). Methods Twelve patients with cDGS underwent transplantation with allogeneic cultured thymus. Objective We sought to confirm and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5497aaf2c51a3e3722a7cc649f13c7e1
http://hdl.handle.net/11379/489605
http://hdl.handle.net/11379/489605
Autor:
A Hoshino, Erwin Pauws, Robert P. Erickson, Gudrun E. Moore, Melissa Lees, Emma Peskett, C Boissin, Konstantinos Mengrelis, E Carta, Philip Stanier, MA Abruzzo
Publikováno v:
Clinical Genetics. 83:352-358
X-linked cleft palate (CPX) is caused by mutations in the gene encoding the TBX22 transcription factor and is known to exhibit phenotypic variability, usually involving either a complete, partial or submucous cleft palate, with or without ankylogloss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::945d1d674febd87a1c0b2d3f76a7eb2a
https://doi.org/10.1111/j.1399-0004.2012.01930.x
https://doi.org/10.1111/j.1399-0004.2012.01930.x