Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Konstantinos, Goumas"'
Publikováno v:
ADMET and DMPK, Vol 8, Iss 2, Pp 122-128 (2020)
We explored the potential impact of Crohn’s disease on the intragastric environment of fasted adults with a view to potential effects on intragastric performance of orally administered drugs in the fasted state. Data were collected from 15 healthy
Externí odkaz:
https://doaj.org/article/82447ad3f6644bbc87f6a19046bbca37
Autor:
Stavroula A. Paschou, Fotios Kothonas, Apostolos Lafkas, Alexandros Myroforidis, Vasiliki Loi, Thomais Terzi, Olympia Karagianni, Androniki Poulou, Konstantinos Goumas, Andromachi Vryonidou
Publikováno v:
International Journal of Endocrinology, Vol 2018 (2018)
Background. The aim of this study was to investigate the effect of anti-TNF therapy on glucose and lipid metabolism in nondiabetic, nonobese patients with inflammatory bowel disease (IBD). Patients and Methods. We studied 44 patients with IBD, withou
Externí odkaz:
https://doaj.org/article/46e55ddf7ad34a25bd99142a02ea6746
Autor:
Christos Karathanos, Athanasios D. Giannoukas, Ioannis Papakostas, Konstantinos Goumas, Panagiotis Latzios, Dimitrios Chatzis
Publikováno v:
Phlebology: The Journal of Venous Disease. 36:423-431
Background To assess the treatment of superficial vein thrombosis (SVT) with intermediate dose of tinzaparin in a setting of real world practice. Methods Prospective observational study of consecutive patients treated by vascular physicians in the pr
Publikováno v:
ADMET and DMPK, Vol 8, Iss 2, Pp 122-128 (2020)
ADMET and DMPK
Volume 8
Issue 2
ADMET and DMPK
Volume 8
Issue 2
We explored the potential impact of Crohn’s disease on the intragastric environment of fasted adults with a view to potential effects on intragastric performance of orally administered drugs in the fasted state. Data were collected from 15 healthy
Publikováno v:
Clinical Gastroenterology and Hepatology. 21:A13
Autor:
Maria Vertzoni, Elisabeth Kersten, Konstantinos Goumas, Sarah Sulaiman, Johanna Anlahr, Uwe Muenster, Christos Reppas
Publikováno v:
Journal of pharmaceutical sciences. 110(1)
We characterized the contents of distal ileum and proximal colon of older people from a pharmaceutical product performance perspective, under two extreme situations, i.e. 5 h after a glass of water to fasted volunteers (fasted state) and 5 h after a
Autor:
Androniki Poulou, Andromachi Vryonidou, Grigoris Effraimidis, Vasiliki Loi, Fotios Kothonas, Eleni Palioura, Konstantinos Goumas, Alexandros Myroforidis, Stavroula A Paschou
Publikováno v:
Endocrine Journal. 65:1121-1125
The aim of this study was to investigate for first time the thyroid function in patients with inflammatory bowel disease (IBD) and the potential effect of anti-TNF (tumor necrosis factor) therapy. We evaluated 41 patients with IBD (25M/16F, 36.5 ± 1
Objectives: To quantify the presence of two model highly permeable drugs, paracetamol and danazol, in the upper gastrointestinal lumen under conditions simulating the situation after disintegration of immediate release dosage forms administered in bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::5df8c414a87ebcf2067aa7de477b45d9
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:2903599
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:2903599
Publikováno v:
European Journal of Pharmaceutical Sciences
Objectives To quantify the presence of two model highly permeable drugs, paracetamol and danazol, in the upper gastrointestinal lumen under conditions simulating the situation after disintegration of immediate release dosage forms administered in bio
Autor:
Maria Vertzoni, Nikoletta Fotaki, Mira Symillides, Christos Reppas, Marina Statelova, Konstantinos Goumas, René Holm
Publikováno v:
Statelova, M, Goumas, K, Fotaki, N, Holm, R, Symillides, M, Reppas, C & Vertzoni, M 2020, ' On the Design of Food Effect Studies in Adults for Extrapolating Oral Drug Absorption Data to Infants : an Exploratory Study Highlighting the Importance of Infant Food ', AAPS Journal, vol. 22, no. 1, 6 . https://doi.org/10.1208/s12248-019-0380-4
The AAPS Journal
The AAPS Journal
In the present investigation, it was explored whether food effect on drug absorption in adults is similar with the food effect after administration of an infant meal with the drug product to adults. After confirming lack of pharmaceutical and pharmac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::955e732292b5001cbbcd5b15acdefe33
https://purehost.bath.ac.uk/ws/files/202386757/Paediatric_food_effect_and_meals_adults_AAPS_J.pdf
https://purehost.bath.ac.uk/ws/files/202386757/Paediatric_food_effect_and_meals_adults_AAPS_J.pdf