Zobrazeno 1 - 10
of 954
pro vyhledávání: '"Konstantinidou, P"'
Autor:
De Gregorio, Giuseppe, Ferretti, Lavinia, Pena, Rodrigo C. G., Marthot-Santaniello, Isabelle, Konstantinidou, Maria, Pavlopoulos, John
The study of Greek papyri from ancient Egypt is fundamental for understanding Graeco-Roman Antiquity, offering insights into various aspects of ancient culture and textual production. Palaeography, traditionally used for dating these manuscripts, rel
Externí odkaz:
http://arxiv.org/abs/2408.07779
Generative AI technologies produce increasingly realistic imagery, which, despite its potential for creative applications, can also be misused to produce misleading and harmful content. This renders Synthetic Image Detection (SID) methods essential f
Externí odkaz:
http://arxiv.org/abs/2407.15500
ERK5 suppression overcomes FAK inhibitor resistance in mutant KRAS-driven non-small cell lung cancer
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 10, Pp 2402-2426 (2024)
Abstract Mutated KRAS serves as the oncogenic driver in 30% of non-small cell lung cancers (NSCLCs) and is associated with metastatic and therapy-resistant tumors. Focal Adhesion Kinase (FAK) acts as a mediator in sustaining KRAS-driven lung tumors,
Externí odkaz:
https://doaj.org/article/6d906eadefba4aea98f43f8cb1de0cbe
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/47ff7ce0913c4ee6840ad3516bf81189
Autor:
Maria Felicia Faienza, Flavia Urbano, Federico Anaclerio, Luigi Antonio Moscogiuri, Fani Konstantinidou, Liborio Stuppia, Valentina Gatta
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 5, Pp 4358-4378 (2024)
Alterations in a mother’s metabolism and endocrine system, due to unbalanced nutrition, may increase the risk of both metabolic and non-metabolic disorders in the offspring’s childhood and adulthood. The risk of obesity in the offspring can be de
Externí odkaz:
https://doaj.org/article/b49b264d42c94d7ba2f786b1c4d31080
Autor:
Parthena Konstantinidou, Zuzana Loubalova, Franziska Ahrend, Aleksandr Friman, Miguel Vasconcelos Almeida, Axel Poulet, Filip Horvat, Yuejun Wang, Wolfgang Losert, Hernan Lorenzi, Petr Svoboda, Eric A. Miska, Josien C. van Wolfswinkel, Astrid D. Haase
Publikováno v:
Cell Reports, Vol 43, Iss 10, Pp 114777- (2024)
Summary: PIWI-interacting RNAs (piRNAs) play a crucial role in safeguarding genome integrity by silencing mobile genetic elements. From flies to humans, piRNAs originate from long single-stranded precursors encoded by genomic piRNA clusters. How piRN
Externí odkaz:
https://doaj.org/article/d5ee216aeb984bc49d474c711d1860ea
Publikováno v:
SLAS Discovery, Vol 29, Iss 5, Pp 100165- (2024)
We report the development of a 384-well formatted NanoBRET assay to characterize molecular glues of 14-3-3/client interactions in living cells. The seven isoforms of 14-3-3 are dimeric hub proteins with diverse roles including transcription factor re
Externí odkaz:
https://doaj.org/article/85badde1d71a4181978e99532b926ef2
Autor:
Chiara Di Berardino, Urte Barceviciute, Chiara Camerano Spelta Rapini, Alessia Peserico, Giulia Capacchietti, Nicola Bernabò, Valentina Russo, Valentina Gatta, Fani Konstantinidou, Marisa Donato, Barbara Barboni
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
IntroductionExcessive calorie intake poses a significant threat to female fertility, leading to hormonal imbalances and reproductive challenges. Overconsumption of unhealthy fats exacerbates ovarian dysfunction, with an overproduction of reactive oxy
Externí odkaz:
https://doaj.org/article/3aef036d8bd4400cbab5352d8d8d2f50
Autor:
Krönke, Markus, Eilers, Christine, Dimova, Desislava, Köhler, Melanie, Buschner, Gabriel, Mirzojan, Lilit, Konstantinidou, Lemonia, Makowski, Marcus R., Nagarajah, James, Navab, Nassir, Weber, Wolfgang, Wendler, Thomas
Background: Thyroid volumetry is crucial in diagnosis, treatment and monitoring of thyroid diseases. However, conventional thyroid volumetry with 2D ultrasound is highly operator-dependent. This study compares 2D ultrasound and tracked 3D ultrasound
Externí odkaz:
http://arxiv.org/abs/2108.10118
Publikováno v:
Mobile DNA, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract PIWI-interacting RNAs (piRNAs) are responsible for preventing the movement of transposable elements in germ cells and protect the integrity of germline genomes. In this review, we examine the common elements of piRNA-guided silencing as well
Externí odkaz:
https://doaj.org/article/d3a8e7c26a3d4956bc68bc19ea34b67e