Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Konstantina Soulele"'
Autor:
Konstantina Soulele, Panos Macheras
Publikováno v:
Oral Drug Delivery for Modified Release Formulations. :391-408
Autor:
Panos Theodosiadis, Lida Kalantzi, Antonios Margaritis, Ioannis Halkiadakis, Konstantina Soulele, Dimitrios Koufakis, Evgenia Kanonidou, Anastasios Konstas, Constantinos D Georgakopoulos, Vasiliki Dimera, Michael Lygeros, Elias Zintzaras
Publikováno v:
Medical Hypothesis, Discovery & Innovation in Ophthalmology. 9
Background: This study aimed to evaluate the non-inferiority and safety of a newly developed preservative-free (PF) multi-dose latanoprost/timolol ophthalmic solution, compared with the benzalkonium chloride (BAK)-preserved fixed combination, in pati
Autor:
Antonios Margaritis, Vasiliki Dimera, Constantinos D Georgakopoulos, Panos Theodosiadis, Evgenia Kanonidou, Konstantina Soulele, Lida Kalantzi, Dimitrios Koufakis, Elias Zintzaras, Anastasios Konstas, Ioannis Halkiadakis
Publikováno v:
Medical Hypothesis, Discovery & Innovation in Ophthalmology. 9
Background: The aim of this study was to test the non-inferiority of preservative-free (PF) latanoprost 50 μg/mL multi-dose ophthalmic solution versus the marketed benzalkonium chloride (BAK)-preserved latanoprost 50 μg/mL ophthalmic solution in pa
Autor:
Konstantina Soulele, Vangelis Karalis
Publikováno v:
Xenobiotica. 49:446-456
Ezetimibe is a potent cholesterol absorption inhibitor, with an erratic pharmacokinetic (PK) profile, attributed to an extensive enterohepatic recirculation (EHC). The aim of this study was to develop a population PK model able to adequately characte
Publikováno v:
Biopharmaceutics & Drug Disposition. 38:407-419
Salmeterol (SAL) is a long-acting β2-adrenergic agonist, which is widely used in the therapy of asthma. The aim of this study was to investigate the pharmacokinetics (PK) of inhaled salmeterol in asthma patients using two different dry powder inhale
Autor:
Vangelis Karalis, Konstantina Soulele
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 128
Ezetimibe (EZE) is an extensively used antihyperlipidemic drug with an important cholesterol lowering activity. It undergoes extensive first-pass metabolism to form its active glucuronide metabolite (EZEG). Both drugs exhibit complex pharmacokinetic
Publikováno v:
European Journal of Pharmaceutical Sciences. 80:33-42
The combination of fluticasone propionate (FLP) and salmeterol (SAL) is often used in clinical practice for the treatment of pulmonary disorders. The purpose of this study was to explore the pharmacokinetics (PK) of inhaled FLP and SAL, after concomi
Publikováno v:
Pulmonary pharmacologytherapeutics. 48
Dry powder inhalers containing the budesonide/formoterol combination have currently a well-established position among other inhaled products. Even though their efficacy mainly depends on the local concentrations of the drug they deliver within the lu
Autor:
Konstantina Soulele, Panos Macheras
Publikováno v:
International Journal of Pharmaceutics. 492:344-345
In the case of pediatric medicinal products the selection of an appropriate and palatable liquid dosage form can make the difference between treatment success and failure. Since the recent adoption of Pediatric Regulations in the U.S. and E.U., there