Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Konstantin Tsinman"'
Autor:
Alex Avdeef
Publikováno v:
ADMET and DMPK, Vol 10, Iss 4 (2022)
In memory of Konstantin Tsinman - Chief Scientific Officer at Pion Inc.,
Externí odkaz:
https://doaj.org/article/27e96ec30c06413099add1bf2a261a41
Autor:
Avdeef, Alex
Publikováno v:
ADMET and DMPK
Volume 10
Issue 4
Volume 10
Issue 4
Autor:
Takashi Mano
Publikováno v:
ADMET and DMPK
Volume 10
Issue 4
Volume 10
Issue 4
The ten years of PhysChem Forum-Japan and Konstantin Tsinman’s great contributions to the forum are briefly described.
Autor:
Szabina Kádár, Petra Tőzsér, Brigitta Nagy, Attila Farkas, Zsombor K. Nagy, Oksana Tsinman, Konstantin Tsinman, Dóra Csicsák, Gergely Völgyi, Krisztina Takács-Novák, Enikő Borbás, Bálint Sinkó
Publikováno v:
The AAPS Journal. 24
The work aimed to develop the Absorption Driven Drug Formulation (ADDF) concept, which is a new approach in formulation development to ensure that the drug product meets the expected absorption rate. The concept is built on the solubility-permeabilit
Autor:
Szabina, Kádár, Petra, Tőzsér, Brigitta, Nagy, Attila, Farkas, Zsombor K, Nagy, Oksana, Tsinman, Konstantin, Tsinman, Dóra, Csicsák, Gergely, Völgyi, Krisztina, Takács-Novák, Enikő, Borbás, Bálint, Sinkó
Publikováno v:
The AAPS journal. 24(1)
The work aimed to develop the Absorption Driven Drug Formulation (ADDF) concept, which is a new approach in formulation development to ensure that the drug product meets the expected absorption rate. The concept is built on the solubility-permeabilit
Autor:
Gergely Völgyi, Hajnalka Pataki, Enikő Borbás, Bálint Sinkó, Konstantin Tsinman, Krisztina Takács-Novák, Oksana Tsinman, Dóra Csicsák, Szabina Kádár
Publikováno v:
Molecular Pharmaceutics. 16:4121-4130
In this work, two different approaches have been developed to predict the food effect and the bioequivalence of marketed itraconazole (ITRA) formulations. Kinetic solubility and simultaneous dissolution-permeation tests of three (ITRA) formulations (
Autor:
Marilyn N. Martinez, Raafat Fahmy, Mansoor A. Khan, Xavier Pepin, Jonathan P. Mochel, Sara Carlert, Patrick J. Sinko, Masoud Jamei, Viera Lukacova, D Pade, Murat Cirit, Sid Bhoopathy, Konstantin Tsinman, David C. Sperry, Talia Flanagan, Maria Vertzoni, Christos Reppas, Ben Forbes
Publikováno v:
Dissolution Technologies. 26:38-66
Autor:
Konstantin Tsinman, Oksana Tsinman, Enikő Borbás, Bálint Sinkó, Krisztina Takács-Novák, Petra Tőzsér, Zsombor Kristóf Nagy, Gergely Völgyi
Publikováno v:
Molecular Pharmaceutics. 15:3308-3317
The aim of this research was to investigate the driving force of membrane transport through size-exclusion membranes and to provide a concentration-based mathematical description of it to evaluate whether it can be an alternative for lipophilic membr
Autor:
Bernard Van Eerdenbrugh, Bernd Ulrich Riebesehl, Arnaud Grandeury, Oksana Tsinman, Saijie Zhu, Konstantin Tsinman, Michael Juhnke, Ram Lingamaneni
Publikováno v:
Pharmaceutical Research. 35
The goal of the study was to evaluate a miniaturized dissolution-permeation apparatus (μFLUX™ apparatus) for its ability to benchmark several itraconazole (ITZ) formulations for which in vivo PK data was available in the literature. Untreated and
Publikováno v:
AAPS PharmSciTech. 19(7)
This study described a pH-gradient dissolution method combined with flux measurements as an in vitro tool for assessing the risk of bioavailability reduction due to drug-drug interactions (DDI) caused by acid reducing agents (ARAs). The device incorp