Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Konstantin Schildknecht"'
Autor:
Björn Samans, Marta Rosselló Chornet, Araceli Rosselló Chornet, Janine Jung, Konstantin Schildknecht, Laura Lozza, Lourdes Alos Zaragoza, Javier Hernández Laforet, Nina Babel, Sven Olek
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/96da6c083d2c4abf936b59cd3c08d9af
Autor:
Björn Samans, Marta Rosselló Chornet, Araceli Rosselló Chornet, Janine Jung, Konstantin Schildknecht, Laura Lozza, Lourdes Alos Zaragoza, Javier Hernández Laforet, Nina Babel, Sven Olek
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundThe course of COVID-19 is associated with severe dysbalance of the immune system, causing both leukocytosis and lymphopenia. Immune cell monitoring may be a powerful tool to prognosticate disease outcome. However, SARS-CoV-2 positive subjec
Externí odkaz:
https://doaj.org/article/2d0865247e04405a88fb40c24303ecef
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149016 (2016)
Signal detection in functional magnetic resonance imaging (fMRI) inherently involves the problem of testing a large number of hypotheses. A popular strategy to address this multiplicity is the control of the false discovery rate (FDR). In this work w
Externí odkaz:
https://doaj.org/article/48ea1a3968a64719bd1a1edf536b7ec8
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125587 (2015)
Epigenetic research leads to complex data structures. Since parametric model assumptions for the distribution of epigenetic data are hard to verify we introduce in the present work a nonparametric statistical framework for two-group comparisons. Furt
Externí odkaz:
https://doaj.org/article/d8ee29ea57a049408b685af53f61d232
Autor:
Rudolf Kaaks, Sven Olek, Theron Johnson, Tilman Kühn, Verena A. Katzke, Sandra González Maldonado, Renée T. Fortner, Araceli Rossello Chornet, Konstantin Schildknecht, Charlotte Le Cornet
Table S1 shows partial Spearman correlations between relative immune cell count adjusted for age at blood collection and sex within the subcohort. Table S2 shows cross-sectional associations of circulating immune cell composition and various covariat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43e061c75a1c2cd0c4411920c37ff376
https://doi.org/10.1158/0008-5472.22424692
https://doi.org/10.1158/0008-5472.22424692
Autor:
Rudolf Kaaks, Sven Olek, Theron Johnson, Tilman Kühn, Verena A. Katzke, Sandra González Maldonado, Renée T. Fortner, Araceli Rossello Chornet, Konstantin Schildknecht, Charlotte Le Cornet
Supplementary Figure S1. Stacked bar charts of normalized immune cell counts across strata of baseline characteristics in the sub-cohort (n = 465).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6672af96e72a0f0f26ea30f9d89d9fe4
https://doi.org/10.1158/0008-5472.22424695.v1
https://doi.org/10.1158/0008-5472.22424695.v1
Autor:
Rudolf Kaaks, Sven Olek, Theron Johnson, Tilman Kühn, Verena A. Katzke, Sandra González Maldonado, Renée T. Fortner, Araceli Rossello Chornet, Konstantin Schildknecht, Charlotte Le Cornet
Although ample evidence indicates that immune cell homeostasis is an important prognostic outcome determinant in patients with cancer, few studies have examined whether it also determines cancer risk among initially healthy individuals. We performed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b96b1af2749dd9203b1d8f64d8734bc8
https://doi.org/10.1158/0008-5472.c.6511846.v1
https://doi.org/10.1158/0008-5472.c.6511846.v1
Autor:
Tilman Kühn, Charlotte Le Cornet, Renée T. Fortner, Theron Johnson, Verena Katzke, Sandra González Maldonado, Araceli Rossello Chornet, Rudolf Kaaks, Konstantin Schildknecht, Sven Olek
Publikováno v:
Cancer Res
Although ample evidence indicates that immune cell homeostasis is an important prognostic outcome determinant in patients with cancer, few studies have examined whether it also determines cancer risk among initially healthy individuals. We performed
Epigenetic immunophenotyping in monitoring of SARS-CoV2 vaccine response and COVID-19 disease course
Autor:
Janine Nadine Jung, Ulrich Hoffmueller, Bjoern Samans, Eva Raschke, Marta Rossello Chornet, Konstantin Schildknecht, Laura Lozza, Araceli Rossello Chornet, Lourdes Alos Zaragoza, Javier Hernandez Laforet, Nina Babel, Sven Olek
Publikováno v:
The Journal of Immunology. 208:161.18-161.18
The objective was to explore whether epigenetic immune cell counting can advance efficiency and quality of diagnostic and immune monitoring related to COVID-19. Application areas were monitoring disease course, therapeutic clinical development, and m
Autor:
Nina Babel, Manfred Gossen, Tina Baldinger, Dirk Schürmann, Ulrich Sack, David K. Stevenson, Ronald J. Wong, Udo Baron, Janika Schulze, Rosa Bacchetta, Jeannette Werner, Uwe-Gerd Liebert, Sven Olek, Andreas Grützkau, Carsten Speckmann, Konstantin Schildknecht, Stephan Borte, Andargaschew Mulu
Publikováno v:
Science Translational Medicine. 10
Immune cell profiles provide valuable diagnostic information for hematologic and immunologic diseases. Although it is the most widely applied analytical approach, flow cytometry is limited to liquid blood. Moreover, either analysis must be performed