Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Konstantin Radyushkin"'
Autor:
Alexis Cooper, Tamer Butto, Niklas Hammer, Somanath Jagannath, Desiree Lucia Fend-Guella, Junaid Akhtar, Konstantin Radyushkin, Florian Lesage, Jennifer Winter, Susanne Strand, Jochen Roeper, Ulrich Zechner, Susann Schweiger
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Birk-Barel intellectual disability is an imprinting syndrome due to maternally-only transmitted mutations of KCNK9/TASK3. Here authors are using a heterozygous deletion of the active maternal Kcnk9 allele to model the disease and show phenotypic resc
Externí odkaz:
https://doaj.org/article/fea75db2dad1436d96f90d9e76ec3153
Autor:
Jana Dickmann, Fernando Gonzalez-Uarquin, Sandra Reichel, Dorothea Pichl, Konstantin Radyushkin, Jan Baumgart, Nadine Baumgart
Publikováno v:
Animals, Vol 12, Iss 24, p 3545 (2022)
The CatWalk test relies on the run of mice across the platform to measure a constant speed with low variation. Mice usually require a stimulus to walk to the end of the catwalk. However, such stimuli are usually aversive and can impair welfare. Posit
Externí odkaz:
https://doaj.org/article/ddb4bcb3feec467ca755f7a6215c0b02
Autor:
Constance Vennin, Charlotte Hewel, Hristo Todorov, Marlon Wendelmuth, Konstantin Radyushkin, André Heimbach, Illia Horenko, Sarah Ayash, Marianne B. Müller, Susann Schweiger, Susanne Gerber, Beat Lutz
Publikováno v:
Cells, Vol 11, Iss 21, p 3405 (2022)
Upon chronic stress, a fraction of individuals shows stress resilience, which can prevent long-term mental dysfunction. The underlying molecular mechanisms are complex and have not yet been fully understood. In this study, we performed a data-driven
Externí odkaz:
https://doaj.org/article/1b0cb01d5c2c42c581384d03abefa4b0
Autor:
Frank Bicker, Verica Vasic, Guilherme Horta, Felipe Ortega, Hendrik Nolte, Atria Kavyanifar, Stefanie Keller, Nevenka Dudvarski Stankovic, Patrick N. Harter, Rui Benedito, Beat Lutz, Tobias Bäuerle, Jens Hartwig, Jan Baumgart, Marcus Krüger, Konstantin Radyushkin, Lavinia Alberi, Benedikt Berninger, Mirko H. H. Schmidt
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
The vascular stem cell niche regulates the proliferation and differentiation of neural stem cells (NSCs) in the adult subventricular zone. Here the authors identify EGFL7 as a neurovascular regulator of NSCsin vivo; EGFL7-knockout mice show reduced n
Externí odkaz:
https://doaj.org/article/893b1f84a39b4db9ad2ea276781e4fdb
Autor:
Anna Wierczeiko, Lena Gammel, Konstantin Radyushkin, Vu Thu Thuy Nguyen, Hristo Todorov, Susanne Gerber, Kristina Endres
Publikováno v:
Cells, Vol 10, Iss 3, p 693 (2021)
Physical activity is considered a promising preventive intervention to reduce the risk of developing Alzheimer’s disease (AD). However, the positive effect of therapeutic administration of physical activity has not been proven conclusively yet, lik
Externí odkaz:
https://doaj.org/article/de7cbc7ede694eaf87c891a2498d6331
Autor:
Malena dos Santos Guilherme, Victor F. Zevallos, Aline Pesi, Nicolai M. Stoye, Vu Thu Thuy Nguyen, Konstantin Radyushkin, Andreas Schwiertz, Ulrich Schmitt, Detlef Schuppan, Kristina Endres
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 17, p 6288 (2020)
Wheat amylase trypsin inhibitors (ATIs) represent a common dietary protein component of gluten-containing cereals (wheat, rye, and barley). They act as toll-like receptor 4 ligands, and are largely resistant to intestinal proteases, eliciting a mild
Externí odkaz:
https://doaj.org/article/d8071f9051d446c5bdb9d3bfc2c96697
Autor:
Isabelle Arnoux, Michael Willam, Nadine Griesche, Jennifer Krummeich, Hirofumi Watari, Nina Offermann, Stephanie Weber, Partha Narayan Dey, Changwei Chen, Olivia Monteiro, Sven Buettner, Katharina Meyer, Daniele Bano, Konstantin Radyushkin, Rosamund Langston, Jeremy J Lambert, Erich Wanker, Axel Methner, Sybille Krauss, Susann Schweiger, Albrecht Stroh
Publikováno v:
eLife, Vol 7 (2018)
Catching primal functional changes in early, ‘very far from disease onset’ (VFDO) stages of Huntington’s disease is likely to be the key to a successful therapy. Focusing on VFDO stages, we assessed neuronal microcircuits in premanifest Hdh150
Externí odkaz:
https://doaj.org/article/031434054df44d4c9f2caf98fe3f48e2
Autor:
Katyayani Singh, Desirée Loreth, Bruno Pöttker, Kyra Hefti, Jürgen Innos, Kathrin Schwald, Heidi Hengstler, Lutz Menzel, Clemens J. Sommer, Konstantin Radyushkin, Oliver Kretz, Mari-Anne Philips, Carola A. Haas, Katrin Frauenknecht, Kersti Lilleväli, Bernd Heimrich, Eero Vasar, Michael K. E. Schäfer
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Neuronal growth regulator 1 (NEGR1), a member of the immunoglobulin superfamily cell adhesion molecule subgroup IgLON, has been implicated in neuronal growth and connectivity. In addition, genetic variants in or near the NEGR1 locus have been associa
Externí odkaz:
https://doaj.org/article/f0dfb55d4b1442b48c881bf6dd9dd7f3
Autor:
Amit Agarwal, Mingyue Zhang, Irina Trembak-Duff, Tilmann Unterbarnscheidt, Konstantin Radyushkin, Payam Dibaj, Daniel Martins de Souza, Susann Boretius, Magdalena M. Brzózka, Heinz Steffens, Sebastian Berning, Zenghui Teng, Maike N. Gummert, Martesa Tantra, Peter C. Guest, Katrin I. Willig, Jens Frahm, Stefan W. Hell, Sabine Bahn, Moritz J. Rossner, Klaus-Armin Nave, Hannelore Ehrenreich, Weiqi Zhang, Markus H. Schwab
Publikováno v:
Cell Reports, Vol 8, Iss 4, Pp 1130-1145 (2014)
Neuregulin-1 (NRG1) gene variants are associated with increased genetic risk for schizophrenia. It is unclear whether risk haplotypes cause elevated or decreased expression of NRG1 in the brains of schizophrenia patients, given that both findings hav
Externí odkaz:
https://doaj.org/article/348c7792707c48e085de09cb7e5f19da
Autor:
Dominik Sakry, Angela Neitz, Jeet Singh, Renato Frischknecht, Daniele Marongiu, Fabien Binamé, Sumudhu S Perera, Kristina Endres, Beat Lutz, Konstantin Radyushkin, Jacqueline Trotter, Thomas Mittmann
Publikováno v:
PLoS Biology, Vol 12, Iss 11, p e1001993 (2014)
The role of glia in modulating neuronal network activity is an important question. Oligodendrocyte precursor cells (OPC) characteristically express the transmembrane proteoglycan nerve-glia antigen 2 (NG2) and are unique glial cells receiving synapti
Externí odkaz:
https://doaj.org/article/d70a5bd4aee94c9396a0636c718d1f1b