Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Konstantin O. Nagornov"'
Autor:
Anton N. Kozhinov, Alex Johnson, Konstantin O. Nagornov, Michael Stadlmeier, Warham Lance Martin, Loïc Dayon, John Corthésy, Martin Wühr, Yury O. Tsybin
Publikováno v:
Analytical Chemistry. 95:3712-3719
Publikováno v:
Journal of the American Society for Mass Spectrometry. 33:1113-1125
The time-domain transients in the Fourier transform mass spectrometry (FTMS) analysis of monoclonal antibodies (mAbs) are known to exhibit characteristic isotopic beat patterns. These patterns are defined by the isotopic distributions of all gaseous
Autor:
Sunitha Narasimha, Konstantin O Nagornov, Laure Menin, Antonio Mucciolo, Astrid Rohwedder, Bruno M Humbel, Martin Stevens, Andreas S Thum, Yury O Tsybin, Roshan K Vijendravarma
Publikováno v:
PLoS Biology, Vol 17, Iss 1, p e2006012 (2019)
Oviparous animals across many taxa have evolved diverse strategies that deter egg predation, providing valuable tests of how natural selection mitigates direct fitness loss. Communal egg laying in nonsocial species minimizes egg predation. However, i
Externí odkaz:
https://doaj.org/article/618a4770b44d47ff9f2abf212904ad39
Autor:
Anton N. Kozhinov, Alex Johnson, Konstantin O. Nagornov, Michael Stadlmeier, Warham Lance Martin, Loïc Dayon, John Corthésy, Martin Wühr, Yury O. Tsybin
In tandem mass spectrometry (MS2)-based multiplexed quantitative proteomics, the complement reporter ion approaches (TMTc and TMTproC) were developed to eliminate the ratio-compression problem of conventional MS2 level approaches. Resolving all highm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f625ab7e1571e707570d74b8e64c162c
https://doi.org/10.1101/2022.07.29.501912
https://doi.org/10.1101/2022.07.29.501912
Autor:
Kyle L. Fort, Ralf Zimmermann, Alexander Makarov, Anton N. Kozhinov, Yury O. Tsybin, Christopher P. Rüger, R. Irsig, Paul Kösling, Sven Ehlert, Andreas Walte, Julian Schade, Martin Rigler, Konstantin O. Nagornov
Publikováno v:
Analytical Chemistry. 93:9418-9427
State-of-the-art mass spectrometry with ultraviolet (UV) photoionization is mostly limited to time-of-flight (ToF) mass spectrometers with 1000-10 000 m/Δm mass resolution. However, higher resolution and higher spectral dynamic range mass spectromet
Autor:
Anton N. Kozhinov, Yury O. Tsybin, Tyler J. Williams, Jacob R. Bills, R. Kenneth Marcus, Konstantin O. Nagornov
Publikováno v:
Journal of the American Society for Mass Spectrometry. 32:1224-1236
Isotope ratio (IR) analysis of natural abundance uranium presents a formidable challenge for mass spectrometry (MS): the required spectral dynamic range needs to enable the quantitatively accurate measurement of the
Autor:
David Touboul, Yury O. Tsybin, Konstantin O. Nagornov, Edith Nicol, Alain Brunelle, Anton N. Kozhinov, Oleg Yu. Tsybin
Publikováno v:
Journal of The American Society for Mass Spectrometry
Journal of The American Society for Mass Spectrometry, Springer Verlag (Germany), 2020, 31 (11), pp.2258-2269. ⟨10.1021/jasms.0c00221⟩
Journal of The American Society for Mass Spectrometry, Springer Verlag (Germany), 2020, 31 (11), pp.2258-2269. ⟨10.1021/jasms.0c00221⟩
Ion signal detection at the true (unperturbed) cyclotron frequency instead of the conventional reduced cyclotron frequency has remained a formidable challenge since the inception of Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR
Autor:
Roman A. Zubarev, Zhaowei Meng, Yaroslav Lyutvinskiy, Laure Menin, Alexander Makarov, Xuepei Zhang, Natalia Gasilova, Yury O. Tsybin, Amir Ata Saei, Konstantin O. Nagornov, Anton N. Kozhinov
Traditionally, mass spectrometry (MS) output is the ion abundance plotted versus ionic mass-to-charge ratio m/z. While employing only commercially available equipment, Charge Determination Analysis (CHARDA) adds a third dimension to MS, estimating fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8be067aea89519d3bc5791af74c0dbf
https://doi.org/10.33774/chemrxiv-2021-f6n9j
https://doi.org/10.33774/chemrxiv-2021-f6n9j
Autor:
Victor J Nesatyy, Anton N. Kozhinov, Pasi Virta, Konstantin O. Nagornov, Natalia Gasilova, Yury O. Tsybin, Patrik Holm, Laure Menin
Publikováno v:
Analytical chemistry. 93(38)
The therapeutic efficacy and pharmacokinetics of antibody-drug conjugates (ADCs) in general, and antibody-oligonucleotide conjugates (AOCs) in particular, depend on the drug-to-antibody ratio (DAR) distribution and average value. The DAR is considere
Autor:
Pieter C. Kooijman, David P. A. Kilgour, Yury O. Tsybin, Konstantin O. Nagornov, Shane R. Ellis, Ron M. A. Heeren, Anton N. Kozhinov
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, 9:8, 1-11. Nature Publishing Group
Scientific Reports
Scientific Reports, 9:8, 1-11. Nature Publishing Group
Scientific Reports
Desorption electrospray ionisation-mass spectrometry imaging (DESI-MSI) is a powerful imaging technique for the analysis of complex surfaces. However, the often highly complex nature of biological samples is particularly challenging for MSI approache