Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Konstantin Krismer"'
Autor:
Blythe Adamson, Michael Waskom, Auriane Blarre, Jonathan Kelly, Konstantin Krismer, Sheila Nemeth, James Gippetti, John Ritten, Katherine Harrison, George Ho, Robin Linzmayer, Tarun Bansal, Samuel Wilkinson, Guy Amster, Evan Estola, Corey M. Benedum, Erin Fidyk, Melissa Estévez, Will Shapiro, Aaron B. Cohen
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: As artificial intelligence (AI) continues to advance with breakthroughs in natural language processing (NLP) and machine learning (ML), such as the development of models like OpenAI’s ChatGPT, new opportunities are emerging for efficien
Externí odkaz:
https://doaj.org/article/41579e941470420fa3cc019c9db14c25
Autor:
Konstantin Krismer, Molly A. Bird, Shohreh Varmeh, Erika D. Handly, Anna Gattinger, Thomas Bernwinkler, Daniel A. Anderson, Andreas Heinzel, Brian A. Joughin, Yi Wen Kong, Ian G. Cannell, Michael B. Yaffe
Publikováno v:
Cell Reports, Vol 32, Iss 8, Pp 108064- (2020)
Summary: RNA-binding proteins (RBPs) play critical roles in regulating gene expression by modulating splicing, RNA stability, and protein translation. Stimulus-induced alterations in RBP function contribute to global changes in gene expression, but i
Externí odkaz:
https://doaj.org/article/b2fb1fde168d47caad95d9cb6afb1a18
Autor:
Jared L. Johnson, Tomer M. Yaron, Emily M. Huntsman, Alexander Kerelsky, Junho Song, Amit Regev, Ting-Yu Lin, Katarina Liberatore, Daniel M. Cizin, Benjamin M. Cohen, Neil Vasan, Yilun Ma, Konstantin Krismer, Jaylissa Torres Robles, Bert van de Kooij, Anne E. van Vlimmeren, Nicole Andrée-Busch, Norbert F. Käufer, Maxim V. Dorovkov, Alexey G. Ryazanov, Yuichiro Takagi, Edward R. Kastenhuber, Marcus D. Goncalves, Benjamin D. Hopkins, Olivier Elemento, Dylan J. Taatjes, Alexandre Maucuer, Akio Yamashita, Alexei Degterev, Mohamed Uduman, Jingyi Lu, Sean D. Landry, Bin Zhang, Ian Cossentino, Rune Linding, John Blenis, Peter V. Hornbeck, Benjamin E. Turk, Michael B. Yaffe, Lewis C. Cantley
Publikováno v:
Nature. 613:759-766
Protein phosphorylation is one of the most widespread post-translational modifications in biology1,2. With advances in mass-spectrometry-based phosphoproteomics, 90,000 sites of serine and threonine phosphorylation have so far been identified, and se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24067cbcb16c95a6f48186aaec1c115c
https://doi.org/10.1038/s41586-022-05575-3
https://doi.org/10.1038/s41586-022-05575-3
Autor:
Frank B. Gertler, Sangeeta N. Bhatia, Christopher B. Burge, Michael B. Yaffe, Douglas A. Lauffenburger, Anthony R. Soltis, Mira N. Moufarrej, Konstantin Krismer, Brian A. Joughin, Maria S. Alexis, Liangliang Hao, Nazanin Rohani
Figure S3 shows CA9 localization relative to markers for cell invasion and proliferation in human IDC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::503e373ce29e48161318bcff4ce97f08
https://doi.org/10.1158/0008-5472.22423761
https://doi.org/10.1158/0008-5472.22423761
Autor:
Jared L. Johnson, Tomer M. Yaron, Emily M. Huntsman, Alexander Kerelsky, Junho Song, Amit Regev, Ting-Yu Lin, Katarina Liberatore, Daniel M. Cizin, Benjamin M. Cohen, Neil Vasan, Yilun Ma, Konstantin Krismer, Jaylissa Torres Robles, Bert van de Kooij, Anne E. van Vlimmeren, Nicole Andrée-Busch, Norbert Käufer, Maxim V. Dorovkov, Alexey G. Ryazanov, Yuichiro Takagi, Edward R. Kastenhuber, Marcus D. Goncalves, Olivier Elemento, Dylan J. Taatjes, Alexandre Maucuer, Akio Yamashita, Alexei Degterev, Rune Linding, John Blenis, Peter V. Hornbeck, Benjamin E. Turk, Michael B. Yaffe, Lewis C. Cantley
Protein phosphorylation is one of the most widespread post-translational modifications in biology. With the advent of mass spectrometry-based phosphoproteomics, more than 200,000 sites of serine and threonine phosphorylation have been reported, of wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fba75afb0655e8d4e5e9b6234f8a04b6
https://doi.org/10.1101/2022.05.22.492882
https://doi.org/10.1101/2022.05.22.492882
Autor:
Jennifer Hammelman, Richard I. Sherwood, Konstantin Krismer, David K. Gifford, Budhaditya Banerjee
Publikováno v:
Genome Res
A key mechanism in cellular regulation is the ability of the transcriptional machinery to physically access DNA. Pioneer transcription factors interact with DNA to open chromatin, which subsequently enables changes to gene expression during developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98d7621a8d46a4bcf604a7011224eebc
https://doi.org/10.1101/gr.263228.120
https://doi.org/10.1101/gr.263228.120
Publikováno v:
Nucleic acids research. 50(9)
Genomic interactions provide important context to our understanding of the state of the genome. One question is whether specific transcription factor interactions give rise to genome organization. We introduce spatzie, an R package and a website that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10c675d3bd4160eafb291854df9815e2
https://pubmed.ncbi.nlm.nih.gov/35100401
https://pubmed.ncbi.nlm.nih.gov/35100401
Publikováno v:
Bioinformatics (Oxford, England). 38(9)
Motivation Sequence models based on deep neural networks have achieved state-of-the-art performance on regulatory genomics prediction tasks, such as chromatin accessibility and transcription factor binding. But despite their high accuracy, their cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2688864b820260be6436e70d4b8931fa
https://pubmed.ncbi.nlm.nih.gov/35191481
https://pubmed.ncbi.nlm.nih.gov/35191481
Autor:
Michael B. Yaffe, Maria S. Alexis, Mira N. Moufarrej, Frank B. Gertler, Liangliang Hao, Nazanin Rohani, Konstantin Krismer, Brian A. Joughin, Christopher B. Burge, Douglas A. Lauffenburger, Sangeeta N. Bhatia, Anthony R. Soltis
Publikováno v:
PMC
Acidosis is a fundamental feature of the tumor microenvironment, which directly regulates tumor cell invasion by affecting immune cell function, clonal cell evolution, and drug resistance. Despite the important association of tumor microenvironment a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a43307b9c588c63ff92f8236a14e109
https://hdl.handle.net/1721.1/135868
https://hdl.handle.net/1721.1/135868
Autor:
Erika D. Handly, Daniel A. Anderson, Anna Gattinger, Molly A. Bird, Andreas Heinzel, Shohreh Varmeh, Yi Wen Kong, Konstantin Krismer, Brian A. Joughin, Michael B. Yaffe, Thomas Bernwinkler, Ian G. Cannell
Publikováno v:
Cell reports
Scientific Reports
Cell Reports, Vol 32, Iss 8, Pp 108064-(2020)
Scientific Reports
Cell Reports, Vol 32, Iss 8, Pp 108064-(2020)
SUMMARY RNA-binding proteins (RBPs) play critical roles in regulating gene expression by modulating splicing, RNA stability, and protein translation. Stimulus-induced alterations in RBP function contribute to global changes in gene expression, but id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f67ac0a705226e2e2979dc919c25926c
https://doi.org/10.1101/416743
https://doi.org/10.1101/416743