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pro vyhledávání: '"Konstantin I. Popov"'
Akademický článek
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Autor:
Kesatebrhan Haile Asressu, Jeffery L. Smith, Rebekah J. Dickmander, Nathaniel J. Moorman, James Wellnitz, Konstantin I. Popov, Alison D. Axtman, Timothy M. Willson
Publikováno v:
Pharmaceuticals, Vol 17, Iss 3, p 306 (2024)
A series of 5-benzylamine-substituted pyrimido[4,5-c]quinoline derivatives of the CSNK2A chemical probe SGC-CK2-2 were synthesized with the goal of improving kinase inhibitor cellular potency and antiviral phenotypic activity while maintaining aqueou
Externí odkaz:
https://doaj.org/article/ac7cc4b8443e42e18645c296689c9774
Autor:
Dzhennet K. Aminova, Natalya G. Bondarenko, Konstantin I. Popov, Tatyana A. Shebzukhova, Arushan A. Vartumyan
Publikováno v:
Política e Gestão Educacional, Vol 25, Iss esp.7 (2021)
The paper is devoted to the search for mechanisms for the successfulness formation as the basis for the harmonious development of the personality of schoolchildren in modern education system. The modern “Pepsi” generation is apathetic and not res
Externí odkaz:
https://doaj.org/article/bf8d66cc3a6a4f48891c1341daff43bb
Publikováno v:
Journal of the American Chemical Society. 145:10445-10450
Autor:
Yao Jiang, Yanqiong Zhang, Janet Y. Leung, Cheng Fan, Konstantin I. Popov, Siyuan Su, Jiayi Qian, Xiaodong Wang, Alisha Holtzhausen, Eric Ubil, Yang Xiang, Ian Davis, Nikolay V. Dokholyan, Gang Wu, Charles M. Perou, William Y. Kim, H. Shelton Earp, Pengda Liu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Hyperactivation of Akt promotes tumorigenesis. Here, the authors show that SAV1, a member of Hippo signalling, interacts with Akt to suppress Akt activity and MERTK-mediated Akt phosphorylation relieves this suppression to facilitate Akt oncogenic ac
Externí odkaz:
https://doaj.org/article/b6df3eea370a40a0932a4398891238b5
Autor:
KNona Liddell
Publikováno v:
Journal of the American Chemical Society. 125:850-850
Autor:
Hirofumi Yoshino, Guowei Yin, Risa Kawaguchi, Konstantin I Popov, Brenda Temple, Mika Sasaki, Satoshi Kofuji, Kara Wolfe, Kaori Kofuji, Koichi Okumura, Jaskirat Randhawa, Akshiv Malhotra, Nazanin Majd, Yoshiki Ikeda, Hiroko Shimada, Emily Rose Kahoud, Sasson Haviv, Shigeki Iwase, John M Asara, Sharon L Campbell, Atsuo T Sasaki
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0224443 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0219436.].
Externí odkaz:
https://doaj.org/article/1d7864211ab34053990ab62a11907bc2
Autor:
Hirofumi Yoshino, Guowei Yin, Risa Kawaguchi, Konstantin I Popov, Brenda Temple, Mika Sasaki, Satoshi Kofuji, Kara Wolfe, Kaori Kofuji, Koichi Okumura, Jaskirat Randhawa, Akshiv Malhotra, Nazanin Majd, Yoshiki Ikeda, Hiroko Shimada, Emily Rose Kahoud, Sasson Haviv, Shigeki Iwase, John M Asara, Sharon L Campbell, Atsuo T Sasaki
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0219436 (2019)
RAS is the founding member of a superfamily of GTPases and regulates signaling pathways involved in cellular growth control. While recent studies have shown that the activation state of RAS can be controlled by lysine ubiquitylation and acetylation,
Externí odkaz:
https://doaj.org/article/537860e2dcb945cb871eddc96579b02f
Publikováno v:
Proteins
Ryanodine receptor 1 (RyR1) is an intracellular calcium ion (Ca(2+)) release channel required for skeletal muscle contraction. Although cryo-electron microscopy identified binding sites of three coactivators Ca(2+), ATP and caffeine (CFF), the mechan
Autor:
Jon-Michael T. Beasley, Daniel R. Korn, Konstantin I. Popov, Reagan L. Dumproff, Zoe L. Sessions, Marielle K. Rath, Vinicius M. Alves, Kevin Causey, Diego Rua, Eugene N. Muratov, Alexander Tropsha
Publikováno v:
Regulatory Toxicology and Pharmacology. 136:105277
Exogenous metal particles and ions from implant devices are known to cause severe toxic events with symptoms ranging from adverse local tissue reactions to systemic toxicities, potentially leading to the development of cancers, heart conditions, and