Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Konstantin I. Izvolsky"'
Autor:
Wellington V. Cardoso, Janice L. Walker, Po-Nien Tsao, Konstantin I. Izvolsky, Maria A. Kukuruzinska, Jining Lu, Felicia Chen
Publikováno v:
Journal of Biological Chemistry. 283:29532-29544
Little is known about the mechanisms by which the lung epithelial progenitors are initially patterned and how proximal-distal boundaries are established and maintained when the lung primordium forms and starts to branch. Here we identified a number o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca36d98fd39e2f0582f723ef872466b2
https://doi.org/10.1074/jbc.m801565200
https://doi.org/10.1074/jbc.m801565200
Publikováno v:
Journal of Biological Chemistry. 280:4834-4841
Genetic studies implicate Fgf10-Fgfr2 signaling as a critical regulator of bud morphogenesis in the embryo. However, little is known about the transcriptional targets of Fgf10 during this process. Here we identified global changes in gene expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52dcc030a029440ee6d5f1db8cb7710d
https://doi.org/10.1074/jbc.m410714200
https://doi.org/10.1074/jbc.m410714200
Kinetics and mechanism of the DNA double helix invasion by pseudocomplementary peptide nucleic acids
Autor:
Christopher Price, Ekaterina Protozanova, Konstantin I. Izvolsky, Maxim D. Frank-Kamenetskii, Peter E. Nielsen, Vadim V. Demidov
Publikováno v:
Proceedings of the National Academy of Sciences. 99:5953-5958
If adenines and thymines in two mutually complementary mixed-base peptide nucleic acid (PNA) oligomers are substituted with diaminopurines and thiouracils, respectively, so-called pseudocomplementary PNAs (pcPNAs) are created. Pairs of pcPNAs have re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0105589a2960c72d0d3d50c4f1dad042
https://doi.org/10.1073/pnas.092127999
https://doi.org/10.1073/pnas.092127999
Autor:
Wellington V. Cardoso, Michelle Vasconcelos, Jun Qian, Jining Lu, Konstantin I. Izvolsky, Po-Nien Tsao
Publikováno v:
Development (Cambridge, England). 136(13)
Although there is accumulated evidence of a role for Notch in the developing lung, it is still unclear how disruption of Notch signaling affects lung progenitor cell fate and differentiation events in the airway epithelium. To address this issue, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::257242c6ce8553d51fa7d282907100c6
https://pubmed.ncbi.nlm.nih.gov/19502490
https://pubmed.ncbi.nlm.nih.gov/19502490
Publikováno v:
Genesis (New York, N.Y. : 2000). 46(1)
Heparan sulfate (HS) proteoglycans modulate the biological activity of a number of growth factors in development, homeostasis, and cancer. Specific modifications of HS chains by HS biosynthetic enzymes have been implicated in growth factor signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e89f008397efb9269189772d7950f63
https://pubmed.ncbi.nlm.nih.gov/18196599
https://pubmed.ncbi.nlm.nih.gov/18196599
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 231(4)
Heparan sulfate (HS) interactions with secreted morphogens such as fibroblast growth factors, hedgehogs, and Wnts are essential for embryonic development. Formation of biologically relevant HS structures is a result of the coordinated action of vario
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd20c5cc969422c9c0ffb34a57982862
https://pubmed.ncbi.nlm.nih.gov/15499561
https://pubmed.ncbi.nlm.nih.gov/15499561
Publikováno v:
Developmental biology. 273(2)
During development, the proximal and distal regions of respiratory tract undergo distinct processes that ultimately give rise to conducting airways and alveoli. To gain insights into the genetic pathways differentially activated in these regions when
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a39854ea30f4b9c472672d4fe72557b
https://pubmed.ncbi.nlm.nih.gov/15328023
https://pubmed.ncbi.nlm.nih.gov/15328023
Autor:
Lin Zhong, Wellington V. Cardoso, Lin Wei, Matthew A. Nugent, Qiang Yu, Konstantin I. Izvolsky
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 285(4)
Fibroblast growth factor (Fgf) 10 is a critical regulator of bud formation during lung morphogenesis. fgf10 is expressed in distal lung mesenchyme at sites of prospective budding from the earliest developmental stages and signals through its epitheli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::767a7d750645be9f6d392291337a02d8
https://pubmed.ncbi.nlm.nih.gov/12818887
https://pubmed.ncbi.nlm.nih.gov/12818887
Publikováno v:
Biochemistry. 39(35)
A new generation of PNAs, so-called pseudocomplementary PNAs (pcPNAs), which are able to target the designated sites on duplex DNA with mixed sequence of purines and pyrimidines via double-duplex invasion mode, has recently been introduced. It has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1d1b0651bdcacee47125d8b9416a05c
https://pubmed.ncbi.nlm.nih.gov/10978178
https://pubmed.ncbi.nlm.nih.gov/10978178
Publikováno v:
Nucleic acids research. 26(21)
We propose a new method for segregation of yeast artificial chromosomes (YACs) from endogenous yeast chromosomes with similar lengths. The method is based on recently developed PNA-assisted rare cleavage (PARC) of genomic DNA. We apply the PARC proce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::329cf246c8497cbe8dc6aa73234d8fcb
https://pubmed.ncbi.nlm.nih.gov/9776769
https://pubmed.ncbi.nlm.nih.gov/9776769