Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Konstantin I. Bakhurin"'
Publikováno v:
STAR Protocols, Vol 1, Iss 2, Pp 100091- (2020)
Summary: Many studies in systems neuroscience use head-fixation preparations for in vivo experimentation. While head-fixation confers several advantages, one major limitation is the lack of behavioral measures that quantify whole-body movements. Here
Externí odkaz:
https://doaj.org/article/b73cabd2941e42eeaf67835aa422438f
Publikováno v:
Frontiers in Integrative Neuroscience, Vol 14 (2020)
Many studies in neuroscience use head-fixed behavioral preparations, which confer a number of advantages, including the ability to limit the behavioral repertoire and use techniques for large-scale monitoring of neural activity. But traditional studi
Externí odkaz:
https://doaj.org/article/0f021e8980e74433b4a371495d33bbe0
Autor:
Kwang Lee, Konstantin I. Bakhurin, Leslie D. Claar, Sandra M. Holley, Natalie C. Chong, Carlos Cepeda, Michael S. Levine, Sotiris C. Masmanidis
Publikováno v:
Cell Reports, Vol 29, Iss 8, Pp 2438-2449.e4 (2019)
Summary: The cortex and thalamus send excitatory projections to the striatum, but little is known about how these inputs, either individually or collectively, regulate striatal dynamics during behavior. The lateral striatum receives overlapping input
Externí odkaz:
https://doaj.org/article/6687792c86704d40893e8394ebcf8d59
Autor:
Konstantin I, Bakhurin, Henry H, Yin
Publikováno v:
Nat Neurosci
The ability to accurately determine when to perform an action is a fundamental brain function and vital to adaptive behavior. The behavioral mechanism and neural circuit for action timing, however, remain largely unknown. Using a new, self-paced acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ef62f50175e76110d0f5577d2715fd59
https://pubmed.ncbi.nlm.nih.gov/35260862
https://pubmed.ncbi.nlm.nih.gov/35260862
Autor:
Leslie D. Claar, Jay Gill, Jacquelyn Nguyen, Jeremy M. Trott, Ayaka Hachisuka, Sotiris C. Masmanidis, Kwang Lee, Konstantin I. Bakhurin
Publikováno v:
Nature Neuroscience. 23:209-216
Midbrain dopamine (DA) neurons encode both reward- and movement-related events and are implicated in disorders of reward processing as well as movement. Consequently, disentangling the contribution of DA neurons in reinforcing versus generating movem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b9b81f09038402c87325796b8203152
https://doi.org/10.1038/s41593-019-0567-0
https://doi.org/10.1038/s41593-019-0567-0
Autor:
Christopher R. Lee, Milad Javaherian, Denise J. Cai, Irene Mollinedo-Gajate, Peyman Golshani, Daniel Aharoni, Alcino J. Silva, Jiannis Taxidis, Baljit S. Khakh, Yu Feng, Lauren M. Vetere, Spyridon Chavlis, Zachary T. Pennington, Konstantin I. Bakhurin, Lucia Page-Harley, Naina Rao, Christina C. Kaba, Ioanna Pandi, Kevin Cheng, Lingxuan Chen, Sotiris C. Masmanidis, Tristan Shuman, Panayiota Poirazi, Chen Yi Yang, Sergio E. Flores, Matthew Shtrahman, Mimi Q La-Vu
Publikováno v:
Nature Neuroscience. 23:229-238
Temporal lobe epilepsy causes severe cognitive deficits, but the circuit mechanisms remain unknown. Interneuron death and reorganization during epileptogenesis may disrupt the synchrony of hippocampal inhibition. To test this, we simultaneously recor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a54e65536d1500d55f402772c57e766d
https://doi.org/10.1038/s41593-019-0559-0
https://doi.org/10.1038/s41593-019-0559-0
Publikováno v:
STAR Protocols, Vol 1, Iss 2, Pp 100091-(2020)
STAR Protocols
STAR Protocols
Summary Many studies in systems neuroscience use head-fixation preparations for in vivo experimentation. While head-fixation confers several advantages, one major limitation is the lack of behavioral measures that quantify whole-body movements. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76b626d93df72ad6dfe50c945db5ab12
http://www.sciencedirect.com/science/article/pii/S2666166720300782
http://www.sciencedirect.com/science/article/pii/S2666166720300782
Autor:
Alexander D. Friedman, Henry H. Yin, Nicholas A. Lusk, Namsoo Kim, Glenn D.R. Watson, Konstantin I. Bakhurin, Xiaoran Li
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
The basal ganglia are widely implicated in action selection and timing, but the relative contributions of the striatonigral (direct) and striatopallidal (indirect) pathways to these functions are still a matter of intense debate. This study investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6825117171cb53457087c68fb2672d98
Autor:
Justin L. Shobe, Leslie D. Claar, Dean V. Buonomano, Sotiris C. Masmanidis, Konstantin I. Bakhurin, Vishwa Goudar
Publikováno v:
The Journal of Neuroscience. 37:854-870
Telling time is fundamental to many forms of learning and behavior, including the anticipation of rewarding events. Although the neural mechanisms underlying timing remain unknown, computational models have proposed that the brain represents time in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da0fda4aa834e92b831096b5ddadebf
https://doi.org/10.1523/jneurosci.1789-16.2016
https://doi.org/10.1523/jneurosci.1789-16.2016