Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Konstantin H Dragnev"'
Autor:
Tian Zhang, Carl Morrison, Sarabjot Pabla, Jason Zhu, Matthew Zibelman, Shannon McCall, Sean T Glenn, Saby George, Yong Hee Lee, Landon C Brown, Chester Kao, Matthew K Labriola, Rajan T Gupta, Daniel J George, Laura J Tafe, Farshid Dayyani, Kunal Desai, Moshe C Ornstein, Emily Kinsey, Jennifer Tran, Konstantin H Dragnev, Mary K Nesline
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 10 (2022)
Background Immunotherapy combinations including ipilimumab and nivolumab are now the standard of care for untreated metastatic renal cell carcinoma (mRCC). Biomarkers of response are lacking to predict patients who will have a favorable or unfavorabl
Externí odkaz:
https://doaj.org/article/9b968140c98748eb94a5b6265a763e29
Autor:
Zhao Yang, Taofeek K Owonikoko, Konstantin H Dragnev, Anne Y Lai, Jessica A Sorrentino, Jared M Weiss, Julie A Rytlewski, Jill Hood, Rajesh K Malik, Jay C Strum, Patrick J Roberts
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Combination treatment with chemotherapy and immune checkpoint inhibitors (ICIs) has demonstrated meaningful clinical benefit to patients. However, chemotherapy-induced damage to the immune system can potentially diminish the efficacy of ch
Externí odkaz:
https://doaj.org/article/69e813bd7bb34caeaa699ef0d1860007
Autor:
Jonathan W. Goldman, Julien Mazieres, Fabrice Barlesi, Konstantin H. Dragnev, Marianna Koczywas, Tuncay Göskel, Alexis B. Cortot, Nicolas Girard, Claas Wesseler, Helge Bischoff, Ernest Nadal, Keunchil Park, Shun Lu, Alvaro Taus, Manuel Cobo, Shawn T. Estrem, Sameera R. Wijayawardana, Kellie Turner, Gerard Joseph Oakley, Karla C. Hurt, Alan Y. Chiang, Anwar M. Hossain, William J. John, Luis Paz-Ares
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
IntroductionJUNIPER compared the efficacy and safety of abemaciclib, a selective cyclin-dependent kinase 4 and 6 inhibitor, with erlotinib in patients with non-small cell lung cancer (NSCLC) harboring a Kirsten rat sarcoma (KRAS) mutation.MethodsJUNI
Externí odkaz:
https://doaj.org/article/4c938db73a4443b18e2317f0a0f304fd
Autor:
Erica B. Bernhardt, Mary D. Chamberlin, Ivan P. Gorlov, Francine B. de Abreu, Katarzyna J. Bloch, Jason D. Peterson, Gregory J. Tsongalis, Keisuke Shirai, Konstantin H. Dragnev, Todd W. Miller, Laura J. Tafe
Publikováno v:
Practical Laboratory Medicine, Vol 21, Iss , Pp e00174- (2020)
Matching of actionable tumor mutations with targeted therapy increases response rates and prolongs survival in lung cancer patients. Drug development and trials targeting genetic alterations are expanding rapidly. We describe the role of a Molecular
Externí odkaz:
https://doaj.org/article/940f51f2fbfb4867bfa973888549ebca
Autor:
Garrett T. Wasp, Christopher Del Prete, Jonathan A.D. Farrell, Konstantin H. Dragnev, Gregory Russo, Graham T. Atkins, Joseph D. Phillips, Gabriel A. Brooks
Publikováno v:
Heliyon, Vol 6, Iss 6, Pp e04319- (2020)
Background: There are limited data and conflicting guideline recommendations regarding the role of neuroimaging in the pretreatment evaluation of non-small cell lung cancer (NSCLC). Methods: We performed a retrospective, pragmatic cohort study of pat
Externí odkaz:
https://doaj.org/article/26806bf74f4547088b394b797c673af2
Autor:
M. Rabie Al-Turkmani, Michael A. Suriawinata, Sophie J. Deharvengt, Donald C. Green, Candice C. Black, Keisuke Shirai, Konstantin H. Dragnev, Gregory J. Tsongalis
Publikováno v:
Practical Laboratory Medicine, Vol 20, Iss , Pp - (2020)
Introduction: Activating mutations in the tyrosine kinase domain of the epidermal growth factor receptor (EGFR) gene in non-small cell lung cancer (NSCLC) patients predicts response to EGFR tyrosine kinase inhibitors (TKIs). The Idylla™ system (Bio
Externí odkaz:
https://doaj.org/article/4a70c4ff1ee74277af76c9f58f402cab
Autor:
Karen L. Reckamp, Mary W. Redman, Konstantin H. Dragnev, Katherine Minichiello, Liza C. Villaruz, Bryan Faller, Tareq Al Baghdadi, Susan Hines, Leah Everhart, Louise Highleyman, Vassiliki Papadimitrakopoulou, Joel W. Neal, Saiama N. Waqar, Jyoti D. Patel, Jhanelle E. Gray, David R. Gandara, Karen Kelly, Roy S. Herbst
Publikováno v:
J Clin Oncol
PURPOSE Resistance to immune checkpoint inhibition (ICI) in advanced non–small-cell lung cancer (NSCLC) represents a major unmet need. Combining ICI with vascular endothelial growth factor (VEGF)/VEGF receptor inhibition has yielded promising resul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c20f9b95c955e29447fc5399eb54405
https://doi.org/10.1200/jco.22.00912
https://doi.org/10.1200/jco.22.00912
Autor:
Shirish M. Gadgeel, Jieling Miao, Jonathan W. Riess, James Moon, Philip C. Mack, Gregory J. Gerstner, Timothy F. Burns, Asma Taj, Wallace L. Akerley, Konstantin H. Dragnev, Noel Laudi, Mary W. Redman, Jhanelle E. Gray, David R. Gandara, Karen Kelly
Publikováno v:
Clinical Cancer Research.
Purpose: Efficacy of MEK inhibitors in KRAS+ NSCLC may differ based on specific KRAS mutations and co-mutations. Our hypothesis was that docetaxel and trametinib would improve activity in KRAS+ NSCLC and specifically in KRAS G12C NSCLC. Patients and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d89719ba527ec54ff861bb3c283c1a5d
https://doi.org/10.1158/1078-0432.ccr-22-3947
https://doi.org/10.1158/1078-0432.ccr-22-3947
Publikováno v:
Frontiers in Cell and Developmental Biology. 11
There are major hurdles to the use of tyrosine kinase inhibitors (TKIs) and any other agents with significant toxicities (which means practically the preponderance of potential effective agents) in the context of prevention/anti-progression (intercep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::594e3ccc5613298fdc592e779e1617b3
https://doi.org/10.3389/fcell.2023.1170444
https://doi.org/10.3389/fcell.2023.1170444
Autor:
Ethan Dmitrovsky, Konstantin H. Dragnev, Sarah J. Freemantle, Yongli Guo, James DiRenzo, Hua Li, Jonathan M. Kurie, Gregory J. Tsongalis, David Johnstone, William Nugent, Bean N. Anyang, Jan H. Beumer, Lorenzo Sempere, Fadzai Chinyengetere, Vincent Memoli, Cherie P. Erkmen, Fabrizio Galimberti, Tian Ma
PDF file - 59K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::293233d2b9247ba7f22547e289c26ff4
https://doi.org/10.1158/1535-7163.22499758
https://doi.org/10.1158/1535-7163.22499758
