Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Konstantin Drexler"'
Autor:
Lukas Heinlein, Roman C. Maron, Achim Hekler, Sarah Haggenmüller, Christoph Wies, Jochen S. Utikal, Friedegund Meier, Sarah Hobelsberger, Frank F. Gellrich, Mildred Sergon, Axel Hauschild, Lars E. French, Lucie Heinzerling, Justin G. Schlager, Kamran Ghoreschi, Max Schlaak, Franz J. Hilke, Gabriela Poch, Sören Korsing, Carola Berking, Markus V. Heppt, Michael Erdmann, Sebastian Haferkamp, Konstantin Drexler, Dirk Schadendorf, Wiebke Sondermann, Matthias Goebeler, Bastian Schilling, Eva Krieghoff-Henning, Titus J. Brinker
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-9 (2024)
Abstract Background Early detection of melanoma, a potentially lethal type of skin cancer with high prevalence worldwide, improves patient prognosis. In retrospective studies, artificial intelligence (AI) has proven to be helpful for enhancing melano
Externí odkaz:
https://doaj.org/article/b94e12d429514a5caf386ed1f4f44417
Autor:
Tanja Elger, Johanna Loibl, Christa Buechler, Sebastian Haferkamp, Jens Werner, Konstantin Drexler, Ulrich Hohenleutner, Karsten Guelow, Claudia Kunst, Arne Kandulski, Pia Goeggelmann, Martina Mueller, Hauke Christian Tews
Publikováno v:
Journal of Medical Case Reports, Vol 18, Iss 1, Pp 1-8 (2024)
Abstract Background Metastatic Crohn’s disease is a rare disorder characterized by various granulomatous skin lesions that occur independently of gastrointestinal tract involvement. However, currently there is no standardized care or specific treat
Externí odkaz:
https://doaj.org/article/1e3366e6a49143b1ac2c752c9c09a215
Autor:
Barbara Schwertner, George Dahdal, Wolfgang Jagla, Luis Grossmann, Konstantin Drexler, Michael P. Krahn, Katja Evert, Mark Berneburg, Sebastian Haferkamp, Christine Ziegler, Eric K. Parkinson, Grit Zahn, Maria E. Mycielska, Andreas Gaumann
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
We have recently shown that cancer cells of various origins take up extracellular citrate through the plasma membrane citrate carrier (pmCiC), a specific plasma membrane citrate transporter. Extracellular citrate is required to support cancer cell me
Externí odkaz:
https://doaj.org/article/0e8a6ba44376475d8a649d023b9f0b09
Autor:
Tirtha Chanda, Katja Hauser, Sarah Hobelsberger, Tabea-Clara Bucher, Carina Nogueira Garcia, Christoph Wies, Harald Kittler, Philipp Tschandl, Cristian Navarrete-Dechent, Sebastian Podlipnik, Emmanouil Chousakos, Iva Crnaric, Jovana Majstorovic, Linda Alhajwan, Tanya Foreman, Sandra Peternel, Sergei Sarap, İrem Özdemir, Raymond L. Barnhill, Mar Llamas-Velasco, Gabriela Poch, Sören Korsing, Wiebke Sondermann, Frank Friedrich Gellrich, Markus V. Heppt, Michael Erdmann, Sebastian Haferkamp, Konstantin Drexler, Matthias Goebeler, Bastian Schilling, Jochen S. Utikal, Kamran Ghoreschi, Stefan Fröhling, Eva Krieghoff-Henning, Reader Study Consortium, Titus J. Brinker
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Artificial intelligence (AI) systems have been shown to help dermatologists diagnose melanoma more accurately, however they lack transparency, hindering user acceptance. Explainable AI (XAI) methods can help to increase transparency, yet oft
Externí odkaz:
https://doaj.org/article/a7c398cf0b3b4b35ad5fc17b7f22b907
Publikováno v:
TATuP – Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis, Vol 33, Iss 1 (2024)
Tools based on machine learning (so-called artificial intelligence, AI) are increasingly being developed to diagnose malignant melanoma in dermatology. This contribution discusses (1) three scenarios for the use of AI in different medical settings, (
Externí odkaz:
https://doaj.org/article/c3eecc463d6c48ad916f78facb081ff5
Autor:
Konstantin Drexler, Lara Bollmann, Sigrid Karrer, Mark Berneburg, Sebastian Haferkamp, Dennis Niebel
Publikováno v:
Biology, Vol 13, Iss 7, p 529 (2024)
(1) Background: Rare skin cancers include epithelial, neuroendocrine, and hematopoietic neoplasias as well as cutaneous sarcomas. Ultraviolet (UV) radiation and sunburns are important drivers for the incidence of certain cutaneous sarcomas; however,
Externí odkaz:
https://doaj.org/article/0a8c6ee3419f43a383e2d95aaff22cfb
Autor:
Dennis Niebel, Paula Kranert, Mark Berneburg, Konstantin Drexler, Maria Isabel vonEichborn, Jan Braess, Michael Allgäuer, Sigrid Karrer
Publikováno v:
Skin Health and Disease, Vol 3, Iss 2, Pp n/a-n/a (2023)
Abstract Carcinoma erysipelatoides (CE) is a rare clinical manifestation of cutaneous metastasis, which mimics inflammatory conditions such as erysipelas. Depending on the site of the originating tumour, unusual manifestations involving different sit
Externí odkaz:
https://doaj.org/article/1c1fcc0a611e4e78a24c207b48959a62
Autor:
Steffen Spoerl, Gerrit Spanier, Elena Reiter, Michael Gerken, Sebastian Haferkamp, Jirka Grosse, Konstantin Drexler, Tobias Ettl, Monika Klinkhammer-Schalke, René Fischer, Silvia Spoerl, Torsten E. Reichert, Christoph Klingelhöffer
Publikováno v:
Head & Face Medicine, Vol 17, Iss 1, Pp 1-10 (2021)
Abstract Background To evaluate predictive clinico-pathological characteristics on outcome in head and neck melanoma (HNM) in a population-based study with particular emphasis on the prognostic effect of sentinel lymph node biopsy (SLNB), Charlson co
Externí odkaz:
https://doaj.org/article/ad93d8aed844497c8a62931a0c6b5928
Autor:
James A. Hutchinson, Katharina Kronenberg, Paloma Riquelme, Jürgen J. Wenzel, Gunther Glehr, Hannah-Lou Schilling, Florian Zeman, Katja Evert, Martin Schmiedel, Marion Mickler, Konstantin Drexler, Florian Bitterer, Laura Cordero, Lukas Beyer, Christian Bach, Josef Koestler, Ralph Burkhardt, Hans J. Schlitt, Dirk Hellwig, Jens M. Werner, Rainer Spang, Barbara Schmidt, Edward K. Geissler, Sebastian Haferkamp
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Checkpoint blocking therapies are used to treat metastatic melanoma, but can have adverse immune-mediated effects, including liver pathology. Here the authors identify an expanded pool of CD4+ effector memory T cells resulting from prior CMV exposure
Externí odkaz:
https://doaj.org/article/f92b658607e1458c8aa40adb3861c519
Autor:
Konstantin Drexler, Hans Drexler, Sigrid Karrer, Michael Landthaler, Sebastian Haferkamp, Florian Zeman, Mark Berneburg, Dennis Niebel
Publikováno v:
Life, Vol 13, Iss 3, p 811 (2023)
(1) Background: Keratinocyte cancer (KC) is associated with exposure to ultraviolet (UV) radiation. However, data are controversial as to whether chronic UV exposure or high intermittent UV exposure are key drivers of carcinogenesis in cutaneous squa
Externí odkaz:
https://doaj.org/article/4ec660c8d15e40a28c9566efc1432b88