Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Konstantia R. Kodella"'
Autor:
Iosif Pediaditakis, Konstantia R. Kodella, Dimitris V. Manatakis, Christopher Y. Le, Chris D. Hinojosa, William Tien-Street, Elias S. Manolakos, Kostas Vekrellis, Geraldine A. Hamilton, Lorna Ewart, Lee L. Rubin, Katia Karalis
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Cellular models of organs have been used to investigate mechanisms of disease. Here the authors generate a human alpha synuclein-induced brain-chip model that recapitulates blood-brain barrier dysfunction, as a potential testing platform for novel th
Externí odkaz:
https://doaj.org/article/4c79c98786c94d82a820ab3e121c9759
Autor:
Iosif Pediaditakis, Konstantia R. Kodella, Dimitris V. Manatakis, Christopher Y. Le, Sonalee Barthakur, Alexander Sorets, Achille Gravanis, Lorna Ewart, Lee L. Rubin, Elias S. Manolakos, Christopher D. Hinojosa, Katia Karalis
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104813- (2022)
Summary: Species differences in brain and blood–brain barrier (BBB) biology hamper the translation of findings from animal models to humans, impeding the development of therapeutics for brain diseases. Here, we present a human organotypic microphys
Externí odkaz:
https://doaj.org/article/493b7bfb538444d6ae5060c22bb9d2ef