Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Konrad Zych"'
Autor:
Szymon Wojciechowski, Monika Majchrzak-Górecka, Paweł Biernat, Krzysztof Odrzywołek, Łukasz Pruss, Konrad Zych, Jan Majta, Kaja Milanowska-Zabel
Publikováno v:
International Journal of Medical Microbiology, Vol 312, Iss 7, Pp 151560- (2022)
The intestinal microbiota is a complex and diverse ecological community that fulfills multiple functions and substantially impacts human health. Despite its plasticity, unfavorable conditions can cause perturbations leading to so-called dysbiosis, wh
Externí odkaz:
https://doaj.org/article/2f3f601f2a3747d393a1b862f3f304fc
Autor:
Jakob Wirbel, Konrad Zych, Morgan Essex, Nicolai Karcher, Ece Kartal, Guillem Salazar, Peer Bork, Shinichi Sunagawa, Georg Zeller
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-27 (2021)
Abstract The human microbiome is increasingly mined for diagnostic and therapeutic biomarkers using machine learning (ML). However, metagenomics-specific software is scarce, and overoptimistic evaluation and limited cross-study generalization are pre
Externí odkaz:
https://doaj.org/article/95e2803d50604883abc56458a1115172
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-8 (2019)
Abstract Background Genetic studies in tetraploids are lagging behind in comparison with studies of diploids as the complex genetics of tetraploids require much more elaborated computational methodologies. Recent advancements in development of molecu
Externí odkaz:
https://doaj.org/article/49eed4b9976341b2a12a464f14d00727
Autor:
Konrad Zych, Basten L Snoek, Mark Elvin, Miriam Rodriguez, K Joeri Van der Velde, Danny Arends, Harm-Jan Westra, Morris A Swertz, Gino Poulin, Jan E Kammenga, Rainer Breitling, Ritsert C Jansen, Yang Li
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171324 (2017)
In high-throughput molecular profiling studies, genotype labels can be wrongly assigned at various experimental steps; the resulting mislabeled samples seriously reduce the power to detect the genetic basis of phenotypic variation. We have developed
Externí odkaz:
https://doaj.org/article/5f3a8bdb80294cfea1ff1b00ba448fad
Autor:
Szymon Wojciechowski, Monika Majchrzak-Górecka, Paweł Biernat, Krzysztof Odrzywołek, Łukasz Pruss, Konrad Zych, null Jan Majta, Kaja Milanowska-Zabel
Publikováno v:
International journal of medical microbiology : IJMM. 312(7)
The intestinal microbiota is a complex and diverse ecological community that fulfills multiple functions and substantially impacts human health. Despite its plasticity, unfavorable conditions can cause perturbations leading to so-called dysbiosis, wh
Autor:
Josefin, Sundh, Hanan, Tanash, Rahi, Arian, Alessandra, Neves-Guimaraes, Katrin, Broberg, Gustav, Lindved, Timo, Kern, Konrad, Zych, Henrik Bjørn, Nielsen, Anders, Halling, Bodil, Ohlsson, Daniel, Jönsson
Publikováno v:
International Journal of Chronic Obstructive Pulmonary Disease
Purpose Infections from the oral microbiome may lead to exacerbations of chronic obstructive pulmonary disease (COPD). We investigated whether advanced dental cleaning could reduce exacerbation frequency. Secondary outcomes were disease-specific heal
Autor:
Peer Bork, Georg Zeller, Morgan Essex, Ece Kartal, Nicolai Karcher, Guillem Salazar, Jakob Wirbel, Shinichi Sunagawa, Konrad Zych
The human microbiome is increasingly mined for diagnostic and therapeutic biomarkers using machine learning (ML). However, metagenomics-specific software is scarce and overoptimistic evaluation and limited cross-study generalization are prevailing is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba61364c6d5296ccf0a4bea9c083e4bf
https://doi.org/10.1101/2020.02.06.931808
https://doi.org/10.1101/2020.02.06.931808
Autor:
Alireza Kashani, Ruby Ponnudurai, Peer Bork, Levi Waldron, Albert Pallejà, Georg Zeller, Paolo Manghi, Satoshi Shiba, Hermann Brenner, Nicola Segata, Hirotsugu Shiroma, Sayaka Mizutani, Emily Vogtmann, Tatsuhiro Shibata, Anita Y. Voigt, Jonas S. Fleck, Rashmi Sinha, Cornelia M. Ulrich, Shinichi Yachida, Nina Habermann, Paul Theodor Pyl, Jakob Wirbel, Takuji Yamada, Davide Serrano, Manimozhiyan Arumugam, Sara Gandini, Ece Kartal, Emma Niméus, Petra Schrotz-King, Andrew Maltez Thomas, Luis Pedro Coelho, Konrad Zych, Shinichi Sunagawa, Alessio Naccarati, Alessio Milanese
Publikováno v:
Wirbel, J, Pyl, P T, Kartal, E, Zych, K, Kashani, A, Milanese, A, Fleck, J S, Voigt, A Y, Palleja, A, Ponnudurai, R, Sunagawa, S, Coelho, L P, Schrotz-King, P, Vogtmann, E, Habermann, N, Niméus, E, Thomas, A M, Manghi, P, Gandini, S, Serrano, D, Mizutani, S, Shiroma, H, Shiba, S, Shibata, T, Yachida, S, Yamada, T, Waldron, L, Naccarati, A, Segata, N, Sinha, R, Ulrich, C M, Brenner, H, Arumugam, M, Bork, P & Zeller, G 2019, ' Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer ', Nature Medicine, vol. 25, no. 4, pp. 679-689 . https://doi.org/10.1038/s41591-019-0406-6
Nat Med
Nature Medicine
Nat Med
Nature Medicine
Association studies have linked microbiome alterations with many human diseases. However, they have not always reported consistent results, thereby necessitating cross-study comparisons. Here, a meta-analysis of eight geographically and technically d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e10216c8f22a1e3d8cfcb2804e67a9cc
https://findresearcher.sdu.dk:8443/ws/files/168756114/118119_2_merged_1550607614.pdf
https://findresearcher.sdu.dk:8443/ws/files/168756114/118119_2_merged_1550607614.pdf
Publikováno v:
BMC Bioinformatics
BMC Bioinformatics 20 (2019) 1
Bmc Bioinformatics, 20:148. BioMed Central Ltd.
BMC Bioinformatics, 20(1)
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-8 (2019)
BMC Bioinformatics 20 (2019) 1
Bmc Bioinformatics, 20:148. BioMed Central Ltd.
BMC Bioinformatics, 20(1)
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-8 (2019)
Background Genetic studies in tetraploids are lagging behind in comparison with studies of diploids as the complex genetics of tetraploids require much more elaborated computational methodologies. Recent advancements in development of molecular techn
Autor:
Wilco Ligterink, Ronny V. L. Joosen, Yang Li, Danny Arends, Joeri van der Velde, Ritsert C. Jansen, Konrad Zych
Publikováno v:
BMC Bioinformatics
Bmc Bioinformatics, 16(1):51. BioMed Central Ltd.
BMC Bioinformatics 16 (2015)
BMC Bioinformatics, 16
Bmc Bioinformatics, 16(1):51. BioMed Central Ltd.
BMC Bioinformatics 16 (2015)
BMC Bioinformatics, 16
Background Genetic markers and maps are instrumental in quantitative trait locus (QTL) mapping in segregating populations. The resolution of QTL localization depends on the number of informative recombinations in the population and how well they are