DosEmi study protocol: a phase IV, multicentre, open-label, crossover study to evaluate non-inferiority of pharmacokinetic-guided reduced dosing compared with conventional dosing of emicizumab in people with haemophilia A

Autor: Marjon H Cnossen, Karin Fijnvandraat, Ron Mathot, Antoine C G Egberts, Rolf T Urbanus, Anouk Donners, Konrad van der Zwet, Ilmar Kruis, Roger Schutgens, Kathelijn Fischer

Publikováno v: BMJ Open, Vol 13, Iss 6 (2023)

Introduction Emicizumab effectively prevents bleeding in people with haemophilia A (PwHA), but is a burden for national healthcare budgets and consequently may limit access. According to the drug label, dosing of emicizumab is based on body weight wi

Externí odkaz: https://doaj.org/article/f47c9a04101c40b8914e5a78633418b0

The Emicizumab Switch: Real-World Data of 251 Pediatric Patients from the Pednet Registry

Autor: Konrad Van Der Zwet, Marloes de Kovel, Jayashree Motwani, Christel Van Geet, Beatrice Nolan, Heidi Glosli, Gili Kenet, Kathelijn Fischer

Publikováno v: Blood. 140:8442-8443

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c936da710eda27b6b1e4854ca0561358
https://doi.org/10.1182/blood-2022-162181

Longitudinal assessment of anti-PGL-I serology in contacts of leprosy patients in Bangladesh

Autor: Anouk van Hooij, Linda Oskam, Jan Hendrik Richardus, Annemieke Geluk, David Pahan, Louis Wilson, Susan J. F. van den Eeden, Konrad van der Zwet, Renate A. Richardus, Khorshed Alam, Roel Faber

Publikováno v: PLoS Neglected Tropical Diseases, Vol 11, Iss 12, p e0006083 (2017)
PLoS Neglected Tropical Diseases, 11(12)
PLoS Neglected Tropical Diseases (print), 11(12):e0006083. Public Library of Science
PLoS Neglected Tropical Diseases

Background Despite elimination efforts, the number of Mycobacterium leprae (M. leprae) infected individuals who develop leprosy, is still substantial. Solid evidence exists that individuals living in close proximity to patients are at increased risk

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a659ab99a2f2cd41feae3fce9ffd39a
https://hdl.handle.net/1765/103922

Data on Monoclonal Antibodies Reported by Marloes de Kovel and Colleagues (Bleeding control improves after switching to emicizumab: Real-world experience of 177 children in the PedNet registry).

Publikováno v: Pediatrics Week; 4/26/2024, p173-173, 1p