Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Konrad T Sawicki"'
Autor:
Hsiang-Chun Chang, Jason Solomon Shapiro, Xinghang Jiang, Grant Senyei, Teruki Sato, Justin Geier, Konrad T Sawicki, Hossein Ardehali
Publikováno v:
eLife, Vol 10 (2021)
Chronic loss of Augmenter of Liver Regeneration (ALR) results in mitochondrial myopathy with cataracts; however, the mechanism for this disorder remains unclear. Here, we demonstrate that loss of ALR, a principal component of the MIA40/ALR protein im
Externí odkaz:
https://doaj.org/article/09ea966f91184bedb8ce060eab6be3c0
Autor:
Hsiang‐Chun Chang, Rongxue Wu, Meng Shang, Tatsuya Sato, Chunlei Chen, Jason S Shapiro, Ting Liu, Anita Thakur, Konrad T Sawicki, Sathyamangla VN Prasad, Hossein Ardehali
Publikováno v:
EMBO Molecular Medicine, Vol 8, Iss 3, Pp 247-267 (2016)
Abstract Excess cellular iron increases reactive oxygen species (ROS) production and causes cellular damage. Mitochondria are the major site of iron metabolism and ROS production; however, few studies have investigated the role of mitochondrial iron
Externí odkaz:
https://doaj.org/article/e6b2dfb41f894ce0b3d39c6f95f0a18b
Autor:
Konrad T. Sawicki, Hongyan Ning, Norrina B. Allen, Mercedes R. Carnethon, Amisha Wallia, James D. Otvos, Issam Ben-Sahra, Elizabeth M. McNally, Janet K. Snell-Bergeon, John T. Wilkins
Publikováno v:
JCI Insight. 8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc8cc0228796e5648cf1254fec50f781
https://doi.org/10.1172/jci.insight.166956
https://doi.org/10.1172/jci.insight.166956
Autor:
Konrad T Sawicki, Hongyan Ning, Keenan Fine, James D Otvos, Mercedes R Carnethon, Ravi V Shah, Venkatesh L Murthy, John T Wilkins
Publikováno v:
Circulation. 147
Introduction: Circulating branched chain amino acid (BCAA) levels are associated with the development of diabetes mellitus (DM) and downstream ASCVD in middle-aged women. It is unknown if BCAAs in young adult men and women are associated with ASCVD e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::763e8490034f345cdb77b7deb4597f8c
https://doi.org/10.1161/circ.147.suppl_1.p200
https://doi.org/10.1161/circ.147.suppl_1.p200
Autor:
John T Wilkins, Waleed Alruwaili, Hongyan Ning, Konrad T Sawicki, Allan D Sniderman, James D Otvos, David R Jacobs, Venkatesh L Murthy, Ravi V Shah, Anand Rohatgi, Norrina B Allen
Publikováno v:
Circulation. 147
Introduction: HDL particles vary in size and concentration. Indices of overall HDL particle concentration (HDL-P) and the concentrations of different HDL size subspecies (small: H1-H3, medium: H4, H5, and large: H6, H7) have differential associations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29ab88d9b078fd3805a9822076a4e173
https://doi.org/10.1161/circ.147.suppl_1.p594
https://doi.org/10.1161/circ.147.suppl_1.p594
Autor:
John T Wilkins, Hongyan Ning, Konrad Sawicki, Konrad T Sawicki, Allan D Sniderman, James D Otvos, Jamal S Rana, Venkatesh Murthy, Venkatesh L Murthy, Ravi V Shah, Norrina B Allen, Donald Lloyd-Jones
Publikováno v:
Circulation. 147
Introduction: Measures of atherogenic particle number (apoB and LDL particle number [LDL-P]) are stronger predictors of atherosclerotic cardiovascular disease (ASCVD) risk than measures of cholesterol concentration (LDL-C, non-HDL-C, total cholestero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51702d8879baf858180113ee1121e902
https://doi.org/10.1161/circ.147.suppl_1.p453
https://doi.org/10.1161/circ.147.suppl_1.p453
Autor:
Konrad T. Sawicki, Hossein Ardehali
Publikováno v:
Nat Cardiovasc Res
Iron is essential to the production of myocardial energy and proteins critical for cardiovascular function. Nearly 50% of patients with heart failure with reduced ejection fraction (HFrEF) meet current criteria for iron deficiency, and there has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::647fedc903790c47f0b88b5992a687ef
https://europepmc.org/articles/PMC9850675/
https://europepmc.org/articles/PMC9850675/
Publikováno v:
Circ Cardiovasc Imaging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d861b23f971b35d86ba7c33230b74fe
https://doi.org/10.1161/circimaging.121.013469
https://doi.org/10.1161/circimaging.121.013469
Publikováno v:
STAR Protocols. 4:102064
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f9c3f129b54a19d7966a4bcc1a7ec66
https://doi.org/10.1016/j.xpro.2023.102064
https://doi.org/10.1016/j.xpro.2023.102064
Autor:
Julie A Fischer, Tanner O Monroe, Lorenzo L Pesce, Konrad T Sawicki, Mattia Quattrocelli, Rosemary Bauer, Samuel D Kearns, Matthew J Wolf, Megan J Puckelwartz, Elizabeth M McNally
Publikováno v:
Human molecular genetics.
Genetic variation in genes regulating metabolism may be advantageous in some settings but not others. The non-failing adult heart relies heavily on fatty acids as a fuel substrate and source of ATP. In contrast, the failing heart favors glucose as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb08ce51acbd12ff4f7829dd42c9a599
https://pubmed.ncbi.nlm.nih.gov/35904451
https://pubmed.ncbi.nlm.nih.gov/35904451