Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Konrad Keller"'
Autor:
Konrad Keller, Klaus Peter Hellriegel
Publikováno v:
Useful and Harmful Interactions of Antibiotics ISBN: 9780429279744
Useful and Harmful Interactions of Antibiotics
Useful and Harmful Interactions of Antibiotics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20582af2b03b79e3276fed544ecf2e69
https://doi.org/10.1201/9780429279744-8
https://doi.org/10.1201/9780429279744-8
Autor:
Jeyaganesh Rajamanickam, Ahmad Akel, Florian Lang, Monica Palmada, Sankarganesh Jeyaraj, Christoph Boehmer, Konrad Keller
Publikováno v:
Diabetes. 55:421-427
Phosphatidylinositol 3-kinase (PI3 kinase) inhibition disrupts the ability of insulin to stimulate GLUT1 and GLUT4 translocation into the cell membrane and thus glucose transport. The effect on GLUT4 but not on GLUT1 is mediated by activation of prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e3efd4772553e7629477e3a16c9fbaa
https://doi.org/10.2337/diabetes.55.02.06.db05-0720
https://doi.org/10.2337/diabetes.55.02.06.db05-0720
Publikováno v:
Biochemistry. 43:931-936
Transmembrane segment 1 of the cysteine-less GLUT 1 glucose transporter was subjected to cysteine-scanning mutagenesis. The majority of single-cysteine mutants were functional transporters, as assessed by 2-deoxy-D-glucose uptake or 3-O-methyl-D-gluc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e12e3d76e785c42c07780e6b5566285
https://doi.org/10.1021/bi030175w
https://doi.org/10.1021/bi030175w
Publikováno v:
FEBS Letters. 555:274-278
The functional consequences of an in vivo heterozygous insertion mutation in the human facilitated glucose transporter isoform 1 (GLUT1) gene were investigated. The resulting frameshift in exon 10 changed the primary structure of the C-terminus from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fbaa49c1ec13fbf6026803eca3bf397
https://doi.org/10.1016/s0014-5793(03)01247-x
https://doi.org/10.1016/s0014-5793(03)01247-x
Publikováno v:
Journal of Magnetic Resonance Imaging. 6:250-254
Oocytes from Xenopus laevis were used as a well-established model to investigate spatially resolved changes in relaxation time (T1) within a cell during exposure to copper complexes by means of 'H-NMR-microscopy. T1 relaxation of intracellular water
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee6dac33749377947eaa64c3a0ae0ba2
https://doi.org/10.1002/jmri.1880060144
https://doi.org/10.1002/jmri.1880060144
Publikováno v:
European Journal of Biochemistry. 227:454-458
Proline residues are thought to play a characteristic structural and/or dynamic role in various membrane proteins [Williams, K. A. & Deber, C. M. (1991) Biochemistry 30, 8919–8923]. By use of site-directed mutagenesis and functional expression of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8490fcdcf04f6853b816e5a3c2067bd7
https://doi.org/10.1111/j.1432-1033.1995.tb20409.x
https://doi.org/10.1111/j.1432-1033.1995.tb20409.x
Autor:
F.M. Brown, Konrad Keller, Sonja Wandel, Michael F. Shanahan, Ingrid Monden, HG Joost, Annette Schürmann
Publikováno v:
Biochemical Journal. 290:497-501
The tryptophan residues 388 and 412 in the glucose transporter GLUT1 were altered to leucine (L) by site-directed mutagenesis and were transiently expressed in COS-7 cells. As assessed by immunoblotting, comparable numbers of glucose transporters wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89521d4c58554021e261e7fcde004158
https://doi.org/10.1042/bj2900497
https://doi.org/10.1042/bj2900497
Autor:
Jeffrey E. Pessin, Isabel Navarro, Amaya Albalat, Josep V. Planas, Encarnación Capilla, Mònica Díaz, Konrad Keller
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 287(2)
Glucose transport across the plasma membrane is mediated by a family of glucose transporter proteins (GLUTs), several of which have been identified in mammalian, avian, and, more recently, in fish species. Here, we report on the cloning of a salmon G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce3ac371b946d890ac9f7c18202fd213
https://pubmed.ncbi.nlm.nih.gov/15113704
https://pubmed.ncbi.nlm.nih.gov/15113704
Publikováno v:
Biological Chemistry. 382
Alanine scanning mutagenesis and the introduction of deletions and insertions were used to address the role of the large cytoplasmic loop in 2-deoxy-D-glucose (2-DOG) uptake by GLUT1 expressed in Xenopus oocytes. Alanine scanning mutagenesis of 29 am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54b81809ce742991a7f9bea92419545b
https://doi.org/10.1515/bc.2001.189
https://doi.org/10.1515/bc.2001.189
Autor:
Jörg Klepper, Thomas Voit, Konrad Keller, Michèl A.A.P. Willemsen, Ingrid Monden, Elena Guertsen
Publikováno v:
FEBS Letters, 498, 1, pp. 104--9
FEBS Letters, 498, 104--9
FEBS Letters, 498, 104--9
Item does not contain fulltext The first autosomal dominant missense mutation (G272A) reported within the human GLUT1 gene and shared by three affected family members was investigated in respect to functional consequences. Substitution of glycine-91
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd5ac431c9eeef1a2b9ae4ffda35f6e8
https://hdl.handle.net/2066/185649
https://hdl.handle.net/2066/185649