Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Konrad J. Dębski"'
Proportions of macronutrients, including specific dietary fats, in prospective anti-Alzheimer’s diet
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Scientific Reports
Scientific Reports
Here we present a novel life-long whole-population study, which enabled us to predict a diet that, in terms of macronutrient proportions, may be prophylactic against Alzheimer’s Disease (AD). The method is based on the existence of oscillations in
Autor:
Bartłomiej Gielniewski, Shamba S Mondal, Bartosz Wojtas, Piotr Przanowski, Michal Dabrowski, Beata Kaza, Konrad J. Dębski, Bozena Kaminska, Aleksandra Cabaj
Publikováno v:
Glia. 67:2312-2328
Microglia are brain-resident, myeloid cells that play important roles in health and brain pathologies. Herein, we report a comprehensive, replicated, false discovery rate-controlled dataset of DNase-hypersensitive (DHS) open chromatin regions for rat
Autor:
Konrad J. Dębski, Anna Muszewska, Marta Hoffman-Sommer, Marcin Grynberg, Jarosław Poznański, Jan Topiński, Krzysztof Pawłowski
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-18 (2018)
Scientific Reports
Scientific Reports
The relationships between polypeptide composition, sequence, structure and function have been puzzling biologists ever since first protein sequences were determined. Here, we study the statistics of occurrence of all possible pentapeptide sequences i
Publikováno v:
Postępy Biochemii.
Chroniczne spożywanie niezdrowej diety jest jedną z przyczyn chorób cywilizacyjnych i wpływa znacząco na średnią długość życia społeczeństw. Wpływ diety na zdrowie jest niezwykle skomplikowany ze względu na chemiczną różnorodność
Publikováno v:
IUBMB Life. 70:50-59
The CacyBP/SIP protein is expressed at a particularly high level in brain, spleen, and various tumors. In this work, we have studied transcriptional regulation of the CacyBP/SIP gene and the influence of increased CacyBP/SIP level on gene expression
Autor:
Anna M. Czarnecka, MSc. Mohammed Imran Khan, Konrad J. Dębski, Cezary Szczylik, Michal Dabrowski
Publikováno v:
American Journal of Physiology-Renal Physiology. 311:F424-F436
In recent years, genome-wide RNA expression analysis has become a routine tool that offers a great opportunity to study and understand the key role of genes that contribute to carcinogenesis. Various microarray platforms and statistical approaches ca
Autor:
Sonja Bröer, Katarzyna Lukasiuk, Paolo Sassone-Corsi, Pierre Baldi, Antoine Ghestem, Maxime Guye, Johannes Alexander Müller, Wolfgang Löscher, Albert J. Becker, Konrad J. Dębski, Anton Ivanov, Nicholas Ceglia, Giulio E. Brancati, Christophe Bernard, Susanne Schoch, Anna Maria Bot
Publikováno v:
Science advances. 6(41)
Gene and protein expressions display circadian oscillations, which can be disrupted in diseases in most body organs. Whether these oscillations occur in the healthy hippocampus and whether they are altered in epilepsy are not known. We identified mor
Publikováno v:
IEEE computer graphics and applications. 37(6)
Correlation analysis is one of the most popular statistical methods. Despite that, the way research reports correlation is often misleading. The difficulty increases with the amount of information that must be read and interpreted. The proposed CI th
Autor:
Albert J. Becker, Maxime Guye, Nicholas Ceglia, Paolo Sassone-Corsi, Pierre Baldi, Konrad J. Dębski, Giulio Emilio Brancati, Wolfgang Löscher, Katarzyna Lukasiuk, Alexander Muller, Susanne Schoch, Antoine Ghestem, Anton Ivanov, Sonja Bröer, Christophe Bernard, Anna Maria Bot
Gene and protein expressions display circadian oscillations in numerous body organs. These oscillations can be disrupted in diseases, thus contributing to the disease pathology. Whether the molecular architecture of cortical brain regions oscillates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a20055580b79994395abd9d1c0e749
Publikováno v:
IUBMB life. 70(1)
The CacyBP/SIP protein is expressed at a particularly high level in brain, spleen, and various tumors. In this work, we have studied transcriptional regulation of the CacyBP/SIP gene and the influence of increased CacyBP/SIP level on gene expression