Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Konrad Honold"'
Autor:
Michael Cannarile, Valeria Runza, Stefan Weigand, Valerie Meresse, Andrew L. Coveler, Devalingam Mahalingam, Carla van Herpen, Jean-Pierre Delord, Christophe Le Tourneau, Henk Verheul, Sabine Lohmann, Florian Heil, Konrad Honold, Adam Nopora, Edgar Voss, Fabian Birzele
Purpose: CD44, a cell surface glycoprotein, plays important roles in the development, progression, and metastasis of various tumor types. The aim of this study was to investigate how the expression of CD44 isoforms influences the interaction with hya
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0471a2b2e86dfb93e268dd809b75cb3d
https://doi.org/10.1158/1078-0432.c.6524757.v1
https://doi.org/10.1158/1078-0432.c.6524757.v1
Autor:
Michael Cannarile, Valeria Runza, Stefan Weigand, Valerie Meresse, Andrew L. Coveler, Devalingam Mahalingam, Carla van Herpen, Jean-Pierre Delord, Christophe Le Tourneau, Henk Verheul, Sabine Lohmann, Florian Heil, Konrad Honold, Adam Nopora, Edgar Voss, Fabian Birzele
Supplementary Methods, Figures (1-6) and Tables (1, 2 and 4). Supplementary Figure 1: Shows how RG7356 blocks binding of CD44-Fc to HA in a concentration dependent manner for two fixed CD44-Fc concentrations. Supplementary Figure 2: Shows hyaluronic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30cdc6774cab1b66f39990c9e3e50834
https://doi.org/10.1158/1078-0432.22461303.v1
https://doi.org/10.1158/1078-0432.22461303.v1
Autor:
Michael Cannarile, Valeria Runza, Stefan Weigand, Valerie Meresse, Andrew L. Coveler, Devalingam Mahalingam, Carla van Herpen, Jean-Pierre Delord, Christophe Le Tourneau, Henk Verheul, Sabine Lohmann, Florian Heil, Konrad Honold, Adam Nopora, Edgar Voss, Fabian Birzele
Supplementary Tables 3, 5, 6 and 7. Supplementary Table 3: Contains the results of the differential gene expression analysis between CD44s HEK and native HEK cells (log ratios on the gene level and FDR corrected p-values) Supplementary Table 5: Conta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b593e404f13a9e85d2d7dcab2575f9e
https://doi.org/10.1158/1078-0432.22461300
https://doi.org/10.1158/1078-0432.22461300
Autor:
Christophe Le Tourneau, Valeria Runza, Florian Heil, Fabian Birzele, Jean Pierre Delord, Carla M.L. van Herpen, Stefan Weigand, Devalingam Mahalingam, Michael A. Cannarile, Konrad Honold, Valerie Meresse, Edgar Voss, Andrew L. Coveler, Adam Nopora, Henk M.W. Verheul, Sabine Lohmann
Publikováno v:
Clinical Cancer Research, 21, 12, pp. 2753-62
Clinical Cancer Research, 21(12), 2753-2762. American Association for Cancer Research Inc.
Birzele, F, Voss, E, Nopora, A, Honold, K, Heil, F, Lohmann, S, Verheul, H, Le Tourneau, C, Delord, J P, Van Herpen, C, Mahalingam, D, Coveler, A L, Meresse, V, Weigand, S, Runza, V & Cannarile, M 2015, ' CD44 Isoform Status Predicts Response to Treatment with Anti-CD44 Antibody in Cancer Patients ', Clinical Cancer Research, vol. 21, no. 12, pp. 2753-2762 . https://doi.org/10.1158/1078-0432.CCR-14-2141
Clinical Cancer Research, 21, 2753-62
Clinical Cancer Research, 21(12), 2753-2762. American Association for Cancer Research Inc.
Birzele, F, Voss, E, Nopora, A, Honold, K, Heil, F, Lohmann, S, Verheul, H, Le Tourneau, C, Delord, J P, Van Herpen, C, Mahalingam, D, Coveler, A L, Meresse, V, Weigand, S, Runza, V & Cannarile, M 2015, ' CD44 Isoform Status Predicts Response to Treatment with Anti-CD44 Antibody in Cancer Patients ', Clinical Cancer Research, vol. 21, no. 12, pp. 2753-2762 . https://doi.org/10.1158/1078-0432.CCR-14-2141
Clinical Cancer Research, 21, 2753-62
Purpose: CD44, a cell surface glycoprotein, plays important roles in the development, progression, and metastasis of various tumor types. The aim of this study was to investigate how the expression of CD44 isoforms influences the interaction with hya
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::459a10030792d5a31a930a09149d2dcb
https://doi.org/10.1158/1078-0432.ccr-14-2141
https://doi.org/10.1158/1078-0432.ccr-14-2141
Autor:
Stefan Scheiblich, Mariana de Wouters, Konrad Honold, Dirk Bernicke, Yvonne Kienast, Stefan Lorenz, Christian Lehmann, Verena Brand, Martina Thier, Alexander Haas, Ute Jucknischke
By non-covalent association after proteolytic cleavage, the pro-domains modulate the activities of the mature growth factor domains across the transforming growth factor-β family. In the case of bone morphogenic protein 9 (BMP9), however, the pro-do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c04b47b484d0ccece08e3535357fccae
https://europepmc.org/articles/PMC4751383/
https://europepmc.org/articles/PMC4751383/
Autor:
Robert Huber, C.B. Breitenlechner, Stefan Scheiblich, Konrad Honold, Stefan Koch, Norman Kairies, Eva Greiter, Wolfgang Schäfer, Hans Koll, Richard A. Engh
Publikováno v:
Journal of Molecular Biology. 353:222-231
c-Src was the first proto-oncoprotein to be identified, and has become the focus of many drug discovery programs. Src structures of a major inactive form have shown how the protein kinase is rigidified by several interdomain interactions; active conf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44d819e5cd19e34e29b9a8760ed9e2a8
https://doi.org/10.1016/j.jmb.2005.08.023
https://doi.org/10.1016/j.jmb.2005.08.023
Autor:
Wolfgang Schäfer, Konrad Honold, Carola Dony, Klaus Kaluza, Angelika Esswein, Oliver Tonn, Sepp Rriegbaum, Andrea Braitmaier
Publikováno v:
Journal of Receptors and Signal Transduction. 20:133-151
A stable recombinant chinese hamster ovary (CHO) cell model system expressing the human type-1 receptor for parathyroid hormone and parathyroid hormone-related peptide (hPTH-R) was established for the analysis of human PTH (hPTH) variants. The cell l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1628c5d54204e7f79df6fcc02785b80c
https://doi.org/10.3109/10799890009150641
https://doi.org/10.3109/10799890009150641
Autor:
Rainer Rudolph, Wolfgang Schäfer, Manfred Wozny, Dietmar Reusch, Angelika Esswein, Konrad Honold, Karl Peter Rücknagel, Hauke Lilie, Ulla Grauschopf
Publikováno v:
Biochemistry. 39(30)
The N-terminal extracellular parts of human G-protein coupled receptor class B, for example, receptors for secretin, glucagon, or parathyroid hormone, are involved in ligand binding. To obtain structural and functional information on the N-terminal r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9af7ca173141c63765f0cc328dd4208
https://pubmed.ncbi.nlm.nih.gov/10913300
https://pubmed.ncbi.nlm.nih.gov/10913300
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 96(10)
Homologous desensitization of G protein-coupled receptors is thought to occur in several steps: binding of G protein-coupled receptor kinases (GRKs) to receptors, receptor phosphorylation, kinase dissociation, and finally binding of β-arrestins to p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::711182538520414564dc7baf9d9fc512
https://pubmed.ncbi.nlm.nih.gov/10318908
https://pubmed.ncbi.nlm.nih.gov/10318908
Publikováno v:
Biofutur. 1997:47
The plasminogene activators described are suitable for the preparation of a drug which stimulates local osteogenesis. The activator is preferably applied locally, incorporated in a carrier, to the place in the body which is to be treated.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e27a937aaf44e19a5eab5938f26f9eac
https://doi.org/10.1016/s0294-3506(99)80346-9
https://doi.org/10.1016/s0294-3506(99)80346-9