Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Konrad Engelhardt"'
Autor:
Elvira De Giglio, Udo Bakowsky, Konrad Engelhardt, Antonello Caponio, Matteo La Pietra, Stefania Cometa, Stefano Castellani, Lorenzo Guerra, Giuseppe Fracchiolla, Maria Luana Poeta, Rosanna Mallamaci, Rosa Angela Cardone, Stefano Bellucci, Adriana Trapani
Publikováno v:
Molecules, Vol 28, Iss 23, p 7706 (2023)
(1) Background: DA-Gelucire® 50/13-based solid lipid nanoparticles (SLNs) administering the neurotransmitter dopamine (DA) and the antioxidant grape-seed-derived proanthocyanidins (grape seed extract, GSE) have been prepared by us in view of a possi
Externí odkaz:
https://doaj.org/article/04b2633af534444082f204f6d52d8146
Autor:
Valeri Roschenko, Abdallah M. Ayoub, Konrad Engelhardt, Jens Schäfer, Muhammad Umair Amin, Eduard Preis, Robert Mandic, Udo Bakowsky
Publikováno v:
Pharmaceutics, Vol 15, Iss 10, p 2412 (2023)
Next to alcohol and tobacco abuse, infection with human papillomaviruses (HPVs) is a major risk factor for developing head and neck squamous cell carcinomas (HNSCCs), leading to 350,000 casualties worldwide each year. Limited therapy options and drug
Externí odkaz:
https://doaj.org/article/6621c4f44a094a8ca9356324fbca9f6e
Autor:
Hannah-Lena Obermann, Ines I. Lederbogen, Jenny Steele, Jens Dorna, Leif Erik Sander, Konrad Engelhardt, Udo Bakowsky, Andreas Kaufmann, Stefan Bauer
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
The innate immune system senses viral and bacterial ribonucleic acid (RNA) via pattern recognition receptors (PRR) leading to subsequent activation of the immune system. One group of RNA sensors is formed by endosomal/lysosomal Toll-like receptors (T
Externí odkaz:
https://doaj.org/article/acc91f308ef140a6a72e1c711f91676c
Autor:
Abraham M. Abraham, Sabrina Wiemann, Ghazala Ambreen, Jenny Zhou, Konrad Engelhardt, Jana Brüßler, Udo Bakowsky, Shu-Ming Li, Robert Mandic, Gabriella Pocsfalvi, Cornelia M. Keck
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 476 (2022)
(1) Background: Extracellular vesicles (EVs) are considered to be efficient nanocarriers for improved drug delivery and can be derived from mammalian or plant cells. Cucumber-derived EVs are not yet described in the literature. Therefore, the aim of
Externí odkaz:
https://doaj.org/article/5be393e7e5f1406cafec695eee2307ec
Autor:
Mohamad Alawak, Alice Abu Dayyih, Ibrahim Awak, Bernd Gutberlet, Konrad Engelhardt, Udo Bakowsky
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629536
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92caeb93153f07d913a55662ab1308d8
https://doi.org/10.1007/978-1-0716-2954-3_9
https://doi.org/10.1007/978-1-0716-2954-3_9
Autor:
Alice Abu Dayyih, Konrad Engelhardt, Muhannad Awak, Jörg W. Bartsch, Gihan Mahmoud, Udo Bakowsky, Shashank Reddy Pinnapireddy, Mohamad Alawak, Lili Duse, Alexander M. König, Jana Brüßler, Nathalie Goergen, Jarmila Jedelská, Imran Tariq
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 158:390-400
Metastatic breast cancer is one of the most common causes of cancer-related death in women worldwide. The transmembrane metalloprotease-disintegrin (ADAM8) protein is highly overexpressed in triple-negative breast cancer (TNBC) cells and potentiates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e5969386955f93d3ce9c3b7a53a7d6d
https://doi.org/10.1016/j.ejpb.2020.12.012
https://doi.org/10.1016/j.ejpb.2020.12.012
Highly Stable Liposomes Based on Tetraether Lipids as a Promising and Versatile Drug Delivery System
Autor:
Aybike Hemetsberger, Eduard Preis, Konrad Engelhardt, Bernd Gutberlet, Frank Runkel, Udo Bakowsky
Publikováno v:
Materials; Volume 15; Issue 19; Pages: 6995
Conventional liposomes often lack stability, limiting their applicability and usage apart from intravenous routes. Nevertheless, their advantages in drug encapsulation and physicochemical properties might be helpful in oral and pulmonary drug deliver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79c638186d01756fcf599fa345a61f91
https://doi.org/10.3390/ma15196995
https://doi.org/10.3390/ma15196995
Autor:
Matthias Wojcik, Alice Abu Dayyih, Ahmed Somaida, Ahmed M. Abdelsalam, Udo Bakowsky, Muhammed U. Amin, Abdallah M. Ayoub, Konrad Engelhardt, Jens Schäfer, Ghazala Ambreen
Publikováno v:
Biomaterials Advances. 134:112543
Parietin (PTN) is an anthraquinone with promising efficacy in the inhibition of cancer cell proliferation and tumor growth. Due to its hydrophobicity, PTN is sparingly soluble under physiological conditions and has a low bioavailability. Hence, we pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09ce7bdfec3abb25f8d5d17475720e56
https://doi.org/10.1016/j.msec.2021.112543
https://doi.org/10.1016/j.msec.2021.112543
Publikováno v:
Macromolecular bioscience. 20(12)
This work focuses on the development of ultrasound contrast vesicles for ultrasound-mediated enhanced transfection of nucleic acids in the cancer cells and projects its application as a tool for diagnostic imaging. The ultrasound contrast vesicles ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da635c13459f13203a4544faa2763e8
https://pubmed.ncbi.nlm.nih.gov/32881380
https://pubmed.ncbi.nlm.nih.gov/32881380
Autor:
Konrad Engelhardt, Shashank Reddy Pinnapireddy, Christian Wölk, Ibrahim Awak, Alice Abu Dayyih, Mohamad Alawak, Alexander M. König, Lili Duse, Gihan Mahmoud, Udo Bakowsky, Jana Brüßler
Publikováno v:
Materials scienceengineering. C, Materials for biological applications. 115
To limit the massive cytotoxicity of chemotherapeutic agents, it is desirable to establish an appropriate subtle blend of formulation design based on a dual-responsive strategy. In this study, a combined therapeutic platform based on magnetic thermos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97d7b24580d75ccf85b74eb72b894194
https://pubmed.ncbi.nlm.nih.gov/32600717
https://pubmed.ncbi.nlm.nih.gov/32600717