Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Konrad, Patyra"'
Autor:
Markus Eszlinger, Alexandra Stephenson, Shideh Mirhadi, Konrad Patyra, Michael F Moran, Moosa Khalil, Jukka Kero, Ralf Paschke
Publikováno v:
European Thyroid Journal, Vol 12, Iss 6, Pp 1-13 (2023)
Objective: Nonautoimmune hyperthyroidism (NAH) is rare and occurs due to a constitutively activating thyroid stimulating hormone receptor (TSHR) mutation. In contrast to other thyroid nodules, no further evaluation for malignancy is recommended for h
Externí odkaz:
https://doaj.org/article/ec09ffec7d2645cb934c4d925b01088d
Autor:
Elin Schoultz, Ellen Johansson, Carmen Moccia, Iva Jakubikova, Naveen Ravi, Shawn Liang, Therese Carlsson, Mikael Montelius, Konrad Patyra, Jukka Kero, Kajsa Paulsson, Henrik Fagman, Martin O. Bergo, Mikael Nilsson
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 2 (2022)
Cancer cells hijack developmental growth mechanisms but whether tissue morphogenesis and architecture modify tumorigenesis is unknown. Here, we characterized a new mouse model of sporadic thyroid carcinogenesis based on inducible expression of BRAF c
Externí odkaz:
https://doaj.org/article/508f6d6970624701985ec7553bd80cdf
Autor:
Konrad Patyra, Kristiina Makkonen, Maria Haanpää, Sinikka Karppinen, Liisa Viikari, Jorma Toppari, Mary Pat Reeve, Jukka Kero
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
BackgroundCentral hypothyroidism (CeH) is a rare condition affecting approximately 1:16 000- 100 000 individuals. Congenital forms can harm normal development if not detected and treated promptly. Clinical and biochemical diagnosis, especially of iso
Externí odkaz:
https://doaj.org/article/2256a7c84fa24fdeb2ace175347017f7
Autor:
François Busquet, Jeanne Laperrouze, Katica Jankovic, Tamara Krsmanovic, Tomasz Ignasiak, Benedetta Leoni, Gordana Apic, Giovanni Asole, Roderic Guigó, Paolo Marangio, Emilio Palumbo, Silvia Perez-Lluch, Valentin Wucher, Anna Hendrika Vlot, Robert Anholt, Trudy Mackay, Beate I. Escher, Nico Grasse, Julia Huchthausen, Riccardo Massei, Thorsten Reemtsma, Stefan Scholz, Gerrit Schüürmann, Maria Bondesson, Peter Cherbas, Jonathan H. Freedman, Stephen Glaholt, Jessica Holsopple, Stephen C. Jacobson, Thomas Kaufman, Ellen Popodi, Joseph J. Shaw, Shannon Smoot, Jason M. Tennessen, Gary Churchill, Christina Cramer von Clausbruch, Thomas Dickmeis, Gaëlle Hayot, Giuseppina Pace, Ravindra Peravali, Carsten Weiss, Nadezda Cistjakova, Xin Liu, Andis Slaitas, James (Ben) Brown, Rafael Ayerbe, Joan Cabellos, Elena Cerro-Gálvez, María Diez-Ortiz, Verónica González, Rubén Martínez, Patricia Solórzano Vives, Rosemary Barnett, Thomas Lawson, Robert G. Lee, Elena Sostare, Mark Viant, Roland Grafström, Vesa Hongisto, Pekka Kohonen, Konrad Patyra, Pradeep Kumar Bhaskar, Marcial Garmendia-Cedillos, Ibraheem Farooq, Brian Oliver, Tom Pohida, Ghadi Salem, Daniel Jacobson, Elisabeth Andrews, Marianne Barnard, Aleksandra Čavoški, Anurag Chaturvedi, John K. Colbourne, David J.T. Epps, Laura Holden, Martin R. Jones, Xiaojing Li, Ferenc Müller, Agata Ormanin-Lewandowska, Luisa Orsini, Ruth Roberts, Ralf J.M. Weber, Jiarui Zhou, Mu-En Chung, Juan Carlos Gonzalez Sanchez, Gaurav D. Diwan, Gurdeep Singh, Uwe Strähle, Robert B. Russell, Dominique Batista, Susanna-Assunta Sansone, Philippe Rocca-Serra, David Du Pasquier, Gregory Lemkine, Barbara Robin-Duchesne, Andrew Tindall
The goal of PrecisionTox is to overcome conceptual barriers to replacing traditional mammalian chemical safety testing by accelerating the discovery of evolutionarily conserved toxicity pathways that are shared by descent among humans and more distan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::876b7659dcbf87711644cfc5deccdefc
https://ora.ox.ac.uk/objects/uuid:bed21c1b-b26c-4b6d-aea0-dce1e848c810
https://ora.ox.ac.uk/objects/uuid:bed21c1b-b26c-4b6d-aea0-dce1e848c810
Autor:
Konrad Patyra, Christoffer Löf, Holger Jaeschke, Hendrik Undeutsch, Huifei Sophia Zheng, Sofia Tyystjärvi, Kamila Puławska, Milena Doroszko, Marcin Chruściel, Britt-Marie Loo, Riikka Kurkijärvi, Fu-Ping Zhang, Chen-Che Jeff Huang, Claes Ohlsson, Andreina Kero, Matti Poutanen, Jorma Toppari, Ralf Paschke, Nafis Rahman, Ilpo Huhtaniemi, Jarmo Jääskeläinen, Jukka Kero
Publikováno v:
Thyroid
BACKGROUND: The human adrenal cortex undergoes several rapid remodeling steps during its lifetime. In rodents, similar remodeling occurs postnatally in the “X-zone” layer through unknown mechanisms. Furthermore, little is known regarding the impa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::284899e225b5924087284d486b7020d1
https://doi.org/10.1089/thy.2021.0535
https://doi.org/10.1089/thy.2021.0535
Autor:
Konrad Patyra, Sinikka Karppinen, Haanpää Maria, Makkonen Kristiina, Pat Reeve Mary, Liisa Viikari, Toppari Jorma, Jukka Kero
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bee8d7b47a984dadda007f89ba607c8f
https://doi.org/10.1530/endoabs.73.oc15.2
https://doi.org/10.1530/endoabs.73.oc15.2
Autor:
Konrad Patyra, Christoffer Löf, Holger Jaeschke, Hendrik Undeutsch, Huifei Zheng, Sofia Tyystjärvi, Kamila Puławska, Milena Doroszko, Marcin Chruściel, Britt-Marie Loo, Riikka Kurkijärvi, Fu-Ping Zhang, Jeff C.C. Huang, Claes Ohlsson, Andreina Kero, Matti Poutanen, Jorma Toppari, Ralf Paschke, Nafis Rahman, Ilpo Huhtaniemi, Jarmo Jääskeläinen, Jukka Kero
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef8da977766100a2e833a0f6aa942197
https://doi.org/10.2139/ssrn.3912543
https://doi.org/10.2139/ssrn.3912543
Autor:
Kajsa Paulsson, Elin Schoultz, Mikael Nilsson, Naveen Ravi, Martin O. Bergo, Iva Jakubikova, Konrad Patyra, Ellen Johansson, Henrik Fagman, Mikael Montelius, Therese Carlsson, Carmen Moccia, Jukka Kero, Shawn Liang
Publikováno v:
Disease Models & Mechanisms
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Cancer cells hijack developmental growth mechanisms but whether tissue morphogenesis and architecture modify tumorigenesis is unknown. Here, we characterized a new mouse model of sporadic thyroid carcinogenesis based on inducible expression of BRAF c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bccdfda78e04cd51dd6d3e544ac689cc
https://pubmed.ncbi.nlm.nih.gov/34379110
https://pubmed.ncbi.nlm.nih.gov/34379110
Publikováno v:
Best Practice & Research Clinical Endocrinology & Metabolism. 32:241-256
The thyroid gland produces thyroid hormones (TH), which are essential regulators for growth, development and metabolism. The thyroid is mainly controlled by the thyroid-stimulating hormone (TSH) that binds to its receptor (TSHR) on thyrocytes and med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d67735b8e63583c76a310c76b54aa5e2
https://doi.org/10.1016/j.beem.2018.03.007
https://doi.org/10.1016/j.beem.2018.03.007
Autor:
aaskelainen J, Erik Schoenmakers, Ilona Zvetkova, Sharone Barone, Ömer Tarım, Christoffer Löf, Liao Xh, Jukka Kero, Nadia Schoenmakers, Hakan Cangul, Eva Goncalves Serra, Eamonn R. Maher, Konrad Patyra, Panudda Srichomkwun, Kristien Boelaert, Halil Saglam, Frankl Fek, Adeline K Nicholas, Samuel Refetoff, ren E, Manoocher Soleimani, Hideyuki Iwayama, Carl A. Anderson, Williams Ed, Timothy Barrett, V. K. K. Chatterjee, Marja Ojaniemi
Publikováno v:
Yearbook of Paediatric Endocrinology.
Defects in genes mediating thyroid hormone biosynthesis result in dyshormonogenic congenital hypothyroidism (CH). Here, we report homozygous truncating mutations in SLC26A7 in 6 unrelated families with goitrous CH and show that goitrous hypothyroidis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9506838af7edba2b7760a75226d41c01
https://doi.org/10.1530/ey.16.3.11
https://doi.org/10.1530/ey.16.3.11