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Akademický článek

Analytical and clinical evaluation of a duplex RT-qPCR assay for the detection and identification of o’nyong-nyong and chikungunya virus

Autor: Konrad M. Wesselmann, Lea Luciani, Laurence Thirion, Xavier de Lamballerie, Remi Charrel, Laura Pezzi

Publikováno v: Emerging Microbes and Infections, Vol 13, Iss 1 (2024)

The mosquito-borne alphavirus o’nyong-nyong virus (ONNV) has proven its potential to cause major human outbreaks. On the African continent, ONNV causes unspecific febrile illness and co-circulates with the close relative chikungunya virus (CHIKV).

Externí odkaz: https://doaj.org/article/2776d314f2b94e328c252d1a1228cd66

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Akademický článek

Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy

Autor: Jean-Louis A. Parmasad, Konrad M. Ricke, Benjamin Nguyen, Morgan G. Stykel, Brodie Buchner-Duby, Amanda Bruce, Haley M. Geertsma, Eric Lian, Nathalie A. Lengacher, Steve M. Callaghan, Alvin Joselin, Julianna J. Tomlinson, Michael G. Schlossmacher, William L. Stanford, Jiyan Ma, Patrik Brundin, Scott D. Ryan, Maxime W. C. Rousseaux

Publikováno v: Cell Death and Disease, Vol 15, Iss 4, Pp 1-13 (2024)

Abstract Parkinson’s disease (PD) is a debilitating neurodegenerative disease characterized by the loss of midbrain dopaminergic neurons (DaNs) and the abnormal accumulation of α-Synuclein (α-Syn) protein. Currently, no treatment can slow nor hal

Externí odkaz: https://doaj.org/article/3314777d4067426182b748c43099f849

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