Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Konrad, Aumann"'
Autor:
Nadia El Khawanky, Amy Hughes, Wenbo Yu, Renier Myburgh, Tony Matschulla, Sanaz Taromi, Konrad Aumann, Jade Clarson, Janaki Manoja Vinnakota, Khalid Shoumariyeh, Cornelius Miething, Angel F. Lopez, Michael P. Brown, Justus Duyster, Lutz Hein, Markus G. Manz, Timothy P. Hughes, Deborah L. White, Agnes S. M. Yong, Robert Zeiser
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
The success of CAR-T cells for treating acute myeloid leukaemia (AML) is hampered by toxicity to normal cells and low CAR-T cell persistence. Here, the authors show that the demethylating compound 5′-Azacitdine increases anti-CD123 CAR-T cell cytot
Externí odkaz:
https://doaj.org/article/fe5a9441efac4b52a10770a66f35954d
Autor:
Eileen Haring, Geoffroy Andrieux, Franziska M. Uhl, Máté Krausz, Michele Proietti, Barbara Sauer, Philipp R. Esser, Stefan F. Martin, Dietmar Pfeifer, Annette Schmitt-Graeff, Justus Duyster, Natalie Köhler, Bodo Grimbacher, Melanie Boerries, Konrad Aumann, Robert Zeiser, Petya Apostolova
Publikováno v:
Haematologica, Vol 107, Iss 7 (2021)
Acute graft-versus-host disease (GvHD) is a life-threatening complication of allogeneic hematopoietic cell transplantation (allo-HCT), a potentially curative treatment for leukemia. Endoplasmic reticulum (ER) stress occurs when the protein folding ca
Externí odkaz:
https://doaj.org/article/3798a575b63446ca8e0e75508ae07a3d
Autor:
Katharina Sies, Corinna Spohr, Albert Gründer, Rumyana Todorova, Franziska Maria Uhl, Julia Huber, Robert Zeiser, Heike Luise Pahl, Heiko Becker, Konrad Aumann, Tilman Brummer, Sebastian Halbach
Publikováno v:
HemaSphere, Vol 3, Iss 2 (2019)
Externí odkaz:
https://doaj.org/article/e8be1cd1ebd94896b7a4b6796222f10e
Autor:
Melanie Langhammer, Julia Schöpf, Timo Jaquet, Katharina Horn, Moritz Angel, Corinna Spohr, Daniel Christen, Franziska Maria Uhl, Tiago Maié, Henrike Jacobi, Thorsten B. Feyerabend, Julia Huber, Marcus Panning, Cassian Sitaru, Ivan Costa, Robert Zeiser, Konrad Aumann, Heiko Becker, Till Braunschweig, Steffen Koschmieder, Khalid Shoumariyeh, Michael Huber, Mirle Schemionek-Reinders, Tilman Brummer, Sebastian Halbach
Publikováno v:
Leukemia.
The persistence of leukemic stem cells (LSCs) represents a problem in the therapy of chronic myeloid leukemia (CML). Hence, it is of utmost importance to explore the underlying mechanisms to develop new therapeutic approaches to cure CML. Using the g
Autor:
Miriam Erlacher, Ying Wu, Patricia Zehnle, Naile Koleci, Geoffroy Andrieux, Lorena Gallego Villar, Jovana Rajak, Konrad Aumann, Melanie Boerries, Charlotte Niemeyer, Sheila Bohler, Christian Flotho
Juvenile myelomonocytic leukemia (JMML) is an aggressive hematopoietic disorder of infancy and early childhood driven by constitutively active RAS signaling and characterized by abnormal proliferation of the granulocytic-monocytic blood cell lineage.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9411e25e1d9705d0a816c91f9f8c6b1c
https://doi.org/10.21203/rs.3.rs-2813473/v1
https://doi.org/10.21203/rs.3.rs-2813473/v1
Autor:
Selina Kiefer, Julia Huber, Hannah Füllgraf, Kristin Sörensen, Agnes Csanadi, Maren Nicole Stillger, Martin Werner, Hans-Eckart Schaefer, Peter Bronsert, Konrad Aumann
Publikováno v:
Cells, Vol 10, Iss 4, p 835 (2021)
Pathological biopsy protocols require tissue marking dye (TMD) for orientation. In some cases (e.g., close margin), additional immunohistochemical analyses can be necessary. Therefore, the correlation between the applied TMD during macroscopy and the
Externí odkaz:
https://doaj.org/article/73ffb42179874881b8fe408872bcc2fb
Autor:
Tamina Rückert, Geoffroy Andrieux, Melanie Boerries, Kathrin Hanke-Müller, Nadine M. Woessner, Stephanie Doetsch, Christoph Schell, Konrad Aumann, Julia Kolter, Annette Schmitt-Graeff, Marcel Schiff, Lukas M. Braun, Eileen Haring, Sandra Kissel, Benjamin A. Siranosian, Ami S. Bhatt, Peter Nordkild, Jan Wehkamp, Benjamin A. H. Jensen, Susana Minguet, Justus Duyster, Robert Zeiser, Natalie Köhler
Publikováno v:
Science translational medicine. 14(676)
Acute graft-versus-host disease (aGVHD), which is driven by allogeneic T cells, has a high mortality rate and limited treatment options. Human β-defensin 2 (hBD-2) is an endogenous epithelial cell–derived host-defense peptide. In addition to its a
Autor:
Máté Krausz, Justus Duyster, Bodo Grimbacher, Geoffroy Andrieux, Robert Zeiser, Stefan F. Martin, Franziska M. Uhl, Dietmar Pfeifer, Barbara Sauer, Natalie Köhler, Eileen Haring, Konrad Aumann, Annette Schmitt-Graeff, Petya Apostolova, Philipp R. Esser, Melanie Boerries, Michele Proietti
Publikováno v:
Haematologica. 107:1538-1554
Acute graft-versus-host disease (GvHD) is a life-threatening complication of allogeneic hematopoietic cell transplantation (allo-HCT), a potentially curative treatment for leukemia. Endoplasmic reticulum (ER) stress occurs when the protein folding ca
Autor:
Melanie Boerries, Oliver Thomusch, Michael Rassner, Matthias Kroiss, Paul la Rosee, Juri Ruf, Konrad Aumann, Cornelius Miething, Christine Dierks, Patrick Metzger, Tilmann Schumacher, Nikolas von Bubnoff, Selina Kiefer, Katharina Laubner, Christian Weißenberger, Claudius Klein, Andreas Zielke, Harald Weiss, Constantin Smaxwil, Justus Duyster, Philipp T. Meyer, Jochen Seufert
Publikováno v:
Thyroid
Background: Anaplastic thyroid carcinoma (ATC) and metastatic poorly differentiated thyroid carcinomas (PDTCs) are rare aggressive malignancies with poor overall survival (OS) despite extensive multimodal therapy. These tumors are highly proliferativ
Publikováno v:
Die Gynäkologie. 56:157-158