Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Konjeti R Sekhar"'
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0214670 (2019)
Radiation therapy is often combined with androgen deprivation therapy in the treatment of aggressive localized prostate cancer. However, castration-resistant disease may not respond to testosterone deprivation approaches. Enzalutamide is a second-gen
Externí odkaz:
https://doaj.org/article/c2a8a8b5fcbf4569a497866831a60e06
Autor:
Amita R. Banga, Konjeti R. Sekhar, Kayla J. Rayford, Ashutosh Arun, Peace Odiase, Amar P. Garg, Maria F. Lima, Pius N. Nde, Fernando Villalta, Girish Rachakonda
Publikováno v:
Microbiology Research, Vol 13, Iss 4, Pp 721-739 (2022)
Trypanosoma cruzi (T. cruzi), the causative agent of Chagas disease, has infected 6 million people, putting 70 million people at risk worldwide. Presently, very limited drugs are available, and these have severe side effects. Hence, there is an urgen
Externí odkaz:
https://doaj.org/article/c7ef648b155a4e2099e56b079b3b2c22
Autor:
Konjeti R. Sekhar, Simona G. Codreanu, Olivia C. Williams, Jeffrey C. Rathmell, W. Kimryn Rathmell, John A. McLean, Stacy D. Sherrod, Naira Baregamian
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionWe successfully developed a broad spectrum of patient-derived endocrine organoids (PDO) from benign and malignant neoplasms of thyroid, parathyroid, and adrenal glands. In this study, we employed functionally intact parathyroid PDOs from
Externí odkaz:
https://doaj.org/article/42c58611fb444e2e9c4d865f9c1364d3
Autor:
Konjeti R. Sekhar, Michael L. Freeman
Publikováno v:
Cancer Research. 83:1573-1580
Nucleophosmin (NPM1) is frequently mutated in acute myeloid leukemia, and NPM1 expression is elevated in several cancer types. NPM1 is a multifunctional oligomeric protein involved in numerous cellular functions that include participating in liquid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37232f99454241925fa3bc10c6fbdab0
https://doi.org/10.1158/0008-5472.can-22-3631
https://doi.org/10.1158/0008-5472.can-22-3631
Autor:
Naira Baregamian, Konjeti R. Sekhar, Evan S. Krystofiak, Maria Vinogradova, Giju Thomas, Emmanuel Mannoh, Carmen C. Solórzano, Colleen M. Kiernan, Anita Mahadevan-Jansen, Naji Abumrad, Michael L. Freeman, Vivian L. Weiss, Jeffrey C. Rathmell, W. Kimryn Rathmell
Publikováno v:
Surgery. 173:67-75
Recent advancements in 3-dimensional patient-derived organoid models have revolutionized the field of cancer biology. There is an urgent need for development of endocrine tumor organoid models for medullary thyroid carcinoma, adrenocortical carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f602a0c8970c514b45239a8b06ea3911
https://doi.org/10.1016/j.surg.2022.09.027
https://doi.org/10.1016/j.surg.2022.09.027
Autor:
Michael L. Freeman, Konjeti R. Sekhar
Legends for Supplementary Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a15a81e70092719eb1932ae667a067
https://doi.org/10.1158/0008-5472.22747006.v1
https://doi.org/10.1158/0008-5472.22747006.v1
Autor:
Michael L. Freeman, Konjeti R. Sekhar
Nucleophosmin (NPM1) is frequently mutated in acute myeloid leukemia, and NPM1 expression is elevated in several cancer types. NPM1 is a multifunctional oligomeric protein involved in numerous cellular functions that include participating in liquid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a6e664802463a005ff1abe2ccd81490
https://doi.org/10.1158/0008-5472.c.6628636
https://doi.org/10.1158/0008-5472.c.6628636
Autor:
Michael L. Freeman, Konjeti R. Sekhar
The relationship between cancer cell line viability and NPM1 dependency, determined from genome-wide CRISPR-Cas9 screens (https://depmap.org/portal/interactive). A score of zero indicates that a gene is not essential. Common essential genes have a me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ade5dd3aaad97fdbc8bbaea1a2daf95
https://doi.org/10.1158/0008-5472.22747003
https://doi.org/10.1158/0008-5472.22747003
Autor:
Michael L. Freeman, Girish Rachakonda, Kenneth J. Salleng, Joseph L. Roti Roti, Robert P. Van Der Waal, Soumya Sasi, Ling Geng, William Hayes McDonald, Amudhan Venkateswaran, Peter A. Crooks, Penthala Narsimha Reddy, Yerramreddy Thirupathi Reddy, Konjeti R. Sekhar
PDF file - 46KB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9a62dc0fe6866209154512b1cff19b0
https://doi.org/10.1158/1078-0432.22443465.v1
https://doi.org/10.1158/1078-0432.22443465.v1
Autor:
Michael L. Freeman, Girish Rachakonda, Kenneth J. Salleng, Joseph L. Roti Roti, Robert P. Van Der Waal, Soumya Sasi, Ling Geng, William Hayes McDonald, Amudhan Venkateswaran, Peter A. Crooks, Penthala Narsimha Reddy, Yerramreddy Thirupathi Reddy, Konjeti R. Sekhar
Purpose: Radiation therapy continues to be an important therapeutic strategy for providing definitive local/regional control of human cancer. However, oncogenes that harbor driver mutations and/or amplifications can compromise therapeutic efficacy. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c78317a8d510e86afb23b4a699634157
https://doi.org/10.1158/1078-0432.c.6519822
https://doi.org/10.1158/1078-0432.c.6519822