Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Kongyan Niu"'
Autor:
Shuwen Ge, Xueting Wang, Yingqin Wang, Minghui Dong, Dean Li, Kongyan Niu, Tongyao Wang, Rui Liu, Chao Zhao, Nan Liu, Ming Zhong
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108618- (2024)
Summary: Nicotinamide adenine dinucleotide (NAD), a nucleotide-containing metabolite, can be incorporated into the RNA 5′-terminus to result in NAD-capped RNA (NAD-RNA). Since NAD has been heightened as one of the most essential metabolites in cell
Externí odkaz:
https://doaj.org/article/2a83ca38c5eb450a8185e07a7c0645df
Autor:
Dean Li, Shuwen Ge, Yandong Liu, Miaomiao Pan, Xueting Wang, Guojing Han, Sili Zou, Rui Liu, Kongyan Niu, Chao Zhao, Nan Liu, Lefeng Qu
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108558- (2023)
Summary: Nicotinamide adenine dinucleotide (NAD) can be used as an initiating nucleotide in RNA transcription to produce NAD-capped RNA (NAD-RNA). RNA modification by NAD that links metabolite with expressed transcript is a poorly studied epitranscri
Externí odkaz:
https://doaj.org/article/71fc59bdba0942a69598db5091516efb
Autor:
Lu Yang, Zaijun Ma, Han Wang, Kongyan Niu, Ye Cao, Le Sun, Yang Geng, Bo Yang, Feng Gao, Zuolong Chen, Zhen Wu, Qingqing Li, Yong Shen, Xumin Zhang, Hong Jiang, Yelin Chen, Rui Liu, Nan Liu, Yaoyang Zhang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Post-translational protein modifications can affect lifespan and aging but age-dependent ubiquitylation changes have not yet been systematically characterized. Here, the authors analyze age-related proteome and ubiquitylome dynamics in Drosophila and
Externí odkaz:
https://doaj.org/article/f03d59fd69bc4bcba96f8c0cd012a7b5
Publikováno v:
Bio-Protocol, Vol 8, Iss 16 (2018)
Chromatin immunoprecipitation followed by sequencing (ChIP-seq) is a routine procedure in the lab; however, epigenome-wide quantitative comparison among independent ChIP-seq experiments remains a challenge. Here, we contribute an experimental protoco
Externí odkaz:
https://doaj.org/article/42425aa882bc474c99e458f57a3709a5
Autor:
Zaijun Ma, Hui Wang, Yuping Cai, Han Wang, Kongyan Niu, Xiaofen Wu, Huanhuan Ma, Yun Yang, Wenhua Tong, Feng Liu, Zhandong Liu, Yaoyang Zhang, Rui Liu, Zheng-Jiang Zhu, Nan Liu
Publikováno v:
eLife, Vol 7 (2018)
Epigenetic alteration has been implicated in aging. However, the mechanism by which epigenetic change impacts aging remains to be understood. H3K27me3, a highly conserved histone modification signifying transcriptional repression, is marked and maint
Externí odkaz:
https://doaj.org/article/9cf7759066d24f918441bcbfdd73a2ff
Autor:
Dean Li, Shuwen Ge, Yandong Liu, Miaomiao Pan, Xueting Wang, Guojing Han, Sili Zou, Rui Liu, Kongyan Niu, Chao Zhao, Nan Liu, Lefeng Qu
The hub metabolite, nicotinamide adenine dinucleotide (NAD), can be used as an initiating nucleotide in RNA transcription to result in NAD-capped RNA (NAD-RNA). NAD-RNA that intimately connects metabolite with gene expression can be developed as nove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cf6a4ede25aae20f048b639fc5a9dc5
https://doi.org/10.1101/2023.03.23.534034
https://doi.org/10.1101/2023.03.23.534034
Autor:
Kongyan Niu, Jinyang Zhang, Shuwen Ge, Dean Li, Kunfeng Sun, Yingnan You, Jiaqian Qiu, Kun Wang, Xueting Wang, Rui Liu, Yandong Liu, Bing Li, Zheng-Jiang Zhu, Lefeng Qu, Hong Jiang, Nan Liu
Publikováno v:
Nucleic acids research.
The hub metabolite, nicotinamide adenine dinucleotide (NAD), can be used as an initiating nucleotide in RNA synthesis to result in NAD-capped RNAs (NAD-RNA). Since NAD has been heightened as one of the most essential modulators in aging and various a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7376e051a70d20c0784196dc1c662dc
https://pubmed.ncbi.nlm.nih.gov/36477375
https://pubmed.ncbi.nlm.nih.gov/36477375
Autor:
Hao He, Feng Zhang, Kai Jiang, Jing Zhu, Wu Wei, Wu Yang, Nan Liu, Junhao Hu, Luyue Wang, Xiaodong Yuan, Nan Su, Kongyan Niu, Tongtong Wang, Lingjie Li, Chonghe Zhang
Publikováno v:
Hepatology (Baltimore, Md.)
Background and aims HSCs and portal fibroblasts (PFs) are the major sources of collagen-producing myofibroblasts during liver fibrosis, depending on different etiologies. However, the mechanisms by which their dynamic gene expression directs the tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b31b4097f16fcc7f7d5496c1fbf217b1
http://europepmc.org/articles/PMC8597108
http://europepmc.org/articles/PMC8597108
Autor:
Ziyu Sun, Shuangyi Cao, Yedan Zhong, Shuixia Tan, Nan Liu, Han Wang, Junhao Hu, Lihui Qian, Jing Zhao, Junying Yuan, Kongyan Niu, Heling Pan, Linyu Shi
Publikováno v:
Proc Natl Acad Sci U S A
Transforming growth factor β-activated kinase1 (TAK1) encoded by the gene MAP3K7 regulates multiple important downstream effectors involved in immune response, cell death, and carcinogenesis. Hepatocyte-specific deletion of TAK1 in Tak1 ΔHEP mice p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f065809585c873518959fb0d19e6429c
https://doi.org/10.1073/pnas.2005353117
https://doi.org/10.1073/pnas.2005353117
Autor:
Xiaofen Wu, Kongyan Niu, Xiaofan Wang, Jing Zhao, Han Wang, Dean Li, Hui Wang, Ting Miao, Yun Yang, Huanhuan Ma, Yaoyang Zhang, Lei Pan, Rui Liu, Hua Bai, Nan Liu
Publikováno v:
Genetics
Inflammaging refers to low-grade, chronically activated innate immunity that has deleterious effects on healthy lifespan. However, little is known about the intrinsic signaling pathway that elicits innate immune genes during aging. Here, using Drosop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea42365a8f9f690c168e8c61ebc2dd4c
https://doi.org/10.1093/genetics/iyab234
https://doi.org/10.1093/genetics/iyab234