miR-135b-5p Suppresses Androgen Receptor-Enhanced Hepatocellular Carcinoma Cell Proliferation via Regulating the HIF-2α/c-Myc/P27 Signals in vitro

Autor: Kong-Wang Hu, Chun-Hua Wang, Jing-Tao Lu, Shixiang Bao, Shuai Jin

Publikováno v: OncoTargets and therapy

Introduction Hepatocellular carcinoma (HCC) accounts for more than 90% of liver cancers and is ranked as the fifth most common malignancy. Androgen receptor (AR) may promote the progression of HCC at an early stage of the disease. However, this study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a7ebd251d52db5409a54998488390a
https://doi.org/10.2147/ott.s268214

MDM2 SNP309 is an ethnicity-dependent risk factor for digestive tract cancers

Autor: Lei Cao, Maoming Xiong, Kong-Wang Hu, Xiang-Ling Meng, Jiawei Zhang, Bo Chen

Publikováno v: Tumor Biology. 35:3431-3438

Published data on the relationship between T309G polymorphism in the murine double minute 2 (MDM2) gene and susceptibility of digestive tract cancers (DTC) are inconclusive. Thus, the aim of this study is to determine whether MDM2 T309G polymorphism

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a53a972f833710eca4f71ac481137718
https://doi.org/10.1007/s13277-013-1453-0

Retinoid Receptors in Gastric Cancer: Expression and Influence on Prognosis

Autor: Hao Li, Li-Yu Cao, Jin-Fang Ge, Fei-Hu Chen, Kong-Wang Hu

Publikováno v: Asian Pacific Journal of Cancer Prevention. 13:1809-1817

Background: Gastric cancer is frequently lethal despite aggressive multimodal therapies, and new treatment approaches are therefore needed. Retinoids are potential candidate drugs: they prevent cell differentiation, proliferation and malignant transf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79cf8d8199744bdeecac20e93422ed1f
https://doi.org/10.7314/apjcp.2012.13.5.1809

A critical analysis of the relationship between aldehyde dehydrogenases-2 Glu487Lys polymorphism and colorectal cancer susceptibility

Autor: Xiang-Ling Meng, Jiawei Zhang, Maoming Xiong, Kong-Wang Hu, Bo Chen, Zhi-Jian Wei

Publikováno v: Pathology oncology research : POR. 21(3)

Studies investigating the association between genetic polymorphism of aldehyde dehydrogenases-2 (ALDH-2) Glu487Lys and colorectal cancer (CRC) risk have reported conflicting results. Given this uncertainty, we carried out a critical analysis of publi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9c1203910ac7ab5ea5b817e3a8e09bc
https://pubmed.ncbi.nlm.nih.gov/25573590

Stem cell-like circulating tumor cells indicate poor prognosis in gastric cancer.

Autor: Yi-Wen W; Department of Gastrointestinal Surgery, Department of General Surgery, First Affiliated Hospital of Anhui Medical University, Anhui, China., Long-Long L; Department of Gastrointestinal Surgery, Department of General Surgery, First Affiliated Hospital of Anhui Medical University, Anhui, China., Ming L; Department of Gastrointestinal Surgery, Department of General Surgery, First Affiliated Hospital of Anhui Medical University, Anhui, China., Hao L; Department of Pathology, Affiliated Hospital of Anhui Medical University, Anhui, China., Kong-Wang H; Department of Gastrointestinal Surgery, Department of General Surgery, First Affiliated Hospital of Anhui Medical University, Anhui, China.

Publikováno v: Archives of medical science : AMS [Arch Med Sci] 2022 Jul 28; Vol. 18 (5), pp. 1297-1307. Date of Electronic Publication: 2022 Jul 28 (Print Publication: 2022).