Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Kong Hung, Sze"'
Autor:
Peng Gao, Yuanxin Wei, Suying Hou, Pok-Man Lai, Han Liu, Sherlock Shing Chiu Tai, Victor Yat Man Tang, Pradeep Halebeedu Prakash, Kong-Hung Sze, Jonathan Hon Kwan Chen, Hongzhe Sun, Xuechen Li, Richard Yi-Tsun Kao
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 2 (2023)
Staphylococcus aureus is a major human pathogen responsible for a wide range of clinical infections. SaeRS is one of the two-component systems in S. aureus that modulate multiple virulence factors. Although SaeR is required for S. aureus to develop a
Externí odkaz:
https://doaj.org/article/5307efbe8a49412ab673ba50402d56c3
Autor:
Jianwen Situ, Kelvin Hon-Yin Lo, Jian-Piao Cai, Zhiyu Li, Shusheng Wu, Estie Hon-Kiu Shun, Nicholas Foo-Siong Chew, James Yiu-Hung Tsoi, Gabriel Sze-Man Chan, Winson Hei-Man Chan, Cyril Chik-Yan Yip, Kong Hung Sze, Vincent Chi-Chung Cheng, Kwok-Yung Yuen, Siddharth Sridhar
Publikováno v:
JHEP Reports, Vol 5, Iss 9, Pp 100793- (2023)
Background & Aims: Rat hepatitis E virus (Rocahepevirus ratti; HEV-C1) is an emerging cause of hepatitis E that is divergent from conventional human-infecting HEV variants (Paslahepevirus balayani; HEV-A). Validated serological assays for HEV-C1 are
Externí odkaz:
https://doaj.org/article/3635aeb2b2d241e78fa7847b44c46c90
Autor:
Hanjun Zhao, Kelvin K. W. To, Kong-Hung Sze, Timothy Tin-Mong Yung, Mingjie Bian, Hoiyan Lam, Man Lung Yeung, Cun Li, Hin Chu, Kwok-Yung Yuen
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Here Zhao et al. report a promising broad-spectrum antiviral alkaline peptide—P9R—that is active against several respiratory, pH-dependent viruses, including Influenza and SARS-CoV-2. P9R interferes with virus internalization by binding to the vi
Externí odkaz:
https://doaj.org/article/4f2f6aa61091410cbf7c4f2708522cde
Autor:
Matthew K. H. Wong, Mulan He, Kong Hung Sze, Tao Huang, Wendy K. W. Ko, Zhao-Xiang Bian, Anderson O. L. Wong
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Spexin (SPX), a highly conserved neuropeptide, is known to have diverse functions and has been implicated/associated with pathological conditions, including obesity, diabetes, anorexia nervosa, and anxiety/mood disorders. Although most of the studies
Externí odkaz:
https://doaj.org/article/3dd1bd1ef0424ee6817433e3a432e585
Autor:
Shuofeng Yuan, Hin Chu, Jasper Fuk-Woo Chan, Zi-Wei Ye, Lei Wen, Bingpeng Yan, Pok-Man Lai, Kah-Meng Tee, Jingjing Huang, Dongdong Chen, Cun Li, Xiaoyu Zhao, Dong Yang, Man Chun Chiu, Cyril Yip, Vincent Kwok-Man Poon, Chris Chung-Sing Chan, Kong-Hung Sze, Jie Zhou, Ivy Hau-Yee Chan, Kin-Hang Kok, Kelvin Kai-Wang To, Richard Yi-Tsun Kao, Johnson Yiu-Nam Lau, Dong-Yan Jin, Stanley Perlman, Kwok-Yung Yuen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Viruses rely on host cell metabolism for replication, making these pathways potential therapeutic targets. Here, the authors show that AM580, a retinoid derivative and RAR-α agonist, affects replication of several RNA viruses by interfering with the
Externí odkaz:
https://doaj.org/article/c1c5fe348ab54b8eb38874751717d9b6
Autor:
Jie Zhou, Dong Wang, Bosco Ho‐Yin Wong, Cun Li, Vincent Kwok‐Man Poon, Lei Wen, Xiaoyu Zhao, Man Chun Chiu, Xiaojuan Liu, Ziwei Ye, Shuofeng Yuan, Kong‐Hung Sze, Jasper Fuk‐Woo Chan, Hin Chu, Kelvin Kai‐Wang To, Kwok Yung Yuen
Publikováno v:
EMBO Molecular Medicine, Vol 11, Iss 1, Pp 1-14 (2018)
Abstract Glycine decarboxylase (GLDC) was prioritized as a candidate susceptibility gene to severe influenza in humans. The higher expression of GLDC derived from genetic variations may confer a higher risk to H7N9 and severe H1N1 infection. We sough
Externí odkaz:
https://doaj.org/article/665342808ef74e9fb985c5b8bd62c4b1
Autor:
Marie C.M. Lin, Hsiang Fu Kung, Ming Liang He, Ren Bao Gan, Tsai Ping Li, Kong Hung Sze, John M. Luk, Sheung Tat Fan, Ronnie T.P. Poon, Ching Chiu Liu, Hai Xiao Chen, Ji Cheng Li, Yi Gao, Zhen Fan Yang, Zan Shen
Supplementary Figure Legends 1-6 from The Kringle 1 Domain of Hepatocyte Growth Factor Has Antiangiogenic and Antitumor Cell Effects on Hepatocellular Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6226e824a8d5640498f0c7d62027b824
https://doi.org/10.1158/0008-5472.22374492.v1
https://doi.org/10.1158/0008-5472.22374492.v1
Autor:
Marie C.M. Lin, Hsiang Fu Kung, Ming Liang He, Ren Bao Gan, Tsai Ping Li, Kong Hung Sze, John M. Luk, Sheung Tat Fan, Ronnie T.P. Poon, Ching Chiu Liu, Hai Xiao Chen, Ji Cheng Li, Yi Gao, Zhen Fan Yang, Zan Shen
The kringle 1 domain of human hepatocyte growth factor (HGFK1) was previously shown to inhibit bovine aortic endothelial cell proliferation, suggesting that it might be an antiangiogenic molecule. Here, we evaluated the in vivo efficacy of a recombin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8aacba587800cf4db7cad4750453c4b7
https://doi.org/10.1158/0008-5472.c.6497469
https://doi.org/10.1158/0008-5472.c.6497469
Autor:
Bao-Zhong Zhang, Jianpiao Cai, Bin Yu, Yanhong Hua, Candy Choiyi Lau, Richard Yi-Tsun Tsun Kao, Kong-Hung Sze, Kwok-Yung Yuen, Jian-Dong Huang
Publikováno v:
BMC Infectious Diseases, Vol 16, Iss 1, Pp 1-8 (2016)
Abstract Background Clostridium difficile-associated disease (CDAD) constitutes a great majority of hospital diarrhea cases in industrialized countries and is induced by two types of large toxin molecules: toxin A (TcdA) and toxin B (TcdB). Developme
Externí odkaz:
https://doaj.org/article/7e412c718d36436a9f8e3830c116013e
Autor:
Bingpeng Yan, Shuofeng Yuan, Jianli Cao, Kingchun Fung, Pok-Man Lai, Feifei Yin, Kong-Hung Sze, Zhenzhi Qin, Yubin Xie, Zi-Wei Ye, Terrence Tsz-Tai Yuen, Kenn Ka-Heng Chik, Jessica Oi-Ling Tsang, Zijiao Zou, Chris Chun-Yiu Chan, Cuiting Luo, Jian-Piao Cai, Kwok-Hung Chan, Tom Wai-Hing Chung, Anthony Raymond Tam, Hin Chu, Dong-Yan Jin, Ivan Fan-Ngai Hung, Kwok-Yung Yuen, Richard Yi-Tsun Kao, Jasper Fuk-Woo Chan
Publikováno v:
International Journal of Biological Sciences. 18:4744-4755
Viruses exploit the host lipid metabolism machinery to achieve efficient replication. We herein characterize the lipids profile reprogramming
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92a875faf64020324e45a17b77cb6264
https://doi.org/10.7150/ijbs.73057
https://doi.org/10.7150/ijbs.73057