Zobrazeno 1 - 10
of 276
pro vyhledávání: '"Konen, Obayashi"'
Autor:
Toshiya Nomura, Mitsuharu Ueda, Masayoshi Tasaki, Yohei Misumi, Teruaki Masuda, Yasuteru Inoue, Yukimoto Tsuda, Masamitsu Okada, Takahiro Okazaki, Kyosuke Kanenawa, Aito Isoguchi, Makoto Nakamura, Konen Obayashi, Satoru Shinriki, Hirotaka Matsui, Taro Yamashita, Yukio Ando
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 14, Iss 1, Pp 1-6 (2019)
Abstract Background Hereditary transthyretin amyloidosis (ATTRv amyloidosis) is caused by a variant transthyretin (TTR), which is a serum protein secreted by the liver. Mass spectrometry (MS) is a useful tool that can detect variant TTRs in serum sam
Externí odkaz:
https://doaj.org/article/6c28f8900d21485d9f672cf6f921e96c
Publikováno v:
Journal of the Neurological Sciences. 449:120668
Autor:
Masamitsu Okada, Hironobu Naiki, Mitsuharu Ueda, Hirotaka Matsui, Toshiya Nomura, Konen Obayashi, Yukio Ando, Kotaro Takamatsu, Keiko Sasada, Akihiko Ueda, Yohei Misumi, Teruaki Masuda, Taro Yamashita, Yasuteru Inoue
Publikováno v:
Neurology and Clinical Neuroscience. 9:37-44
Autor:
Yohei Misumi, Yuri Tabata, Masayoshi Tasaki, Konen Obayashi, Shiori Yamakawa, Toshiya Nomura, Mitsuharu Ueda
Amyloid signature proteins such as serum amyloid P component, apolipoprotein E (ApoE), and ApoA-IV generally co-localise with amyloid, regardless of the types of amyloid precursor protein or the organs. Most of these proteins derive from serum and ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64f6ac074ad1c287fae1da3dc881cd9a
Autor:
Yukimoto Tsuda, Teruaki Masuda, Masayoshi Tasaki, Toshiya Nomura, Yasuteru Inoue, Masamitsu Okada, Konen Obayashi, Taro Yamashita, Mitsuharu Ueda, Yohei Misumi, Yukio Ando
Publikováno v:
Neurology. 93:e1587-e1596
ObjectiveTo elucidate the clinical characteristics of acquired ATTR amyloidosis after domino liver transplantation (DLT) with liver grafts explanted from patients with hereditary variant ATTR (ATTRv) amyloidosis.MethodsWe evaluated the presence of am
Autor:
Mario Nuvolone, Giovanni Ferraro, Paolo Milani, Konen Obayashi, Francesca Lavatelli, Masayoshi Tasaki, Giampaolo Merlini, Marco Basset, Margherita Bozzola, Mitsuharu Ueda, Laura Verga, Giovanni Palladini, Andrea Foli, Laura Obici, Patrizia Morbini, Yukio Ando, Gianluca Capello, Marco Paulli
Publikováno v:
Blood. 134:320-323
TO THE EDITOR: Diagnosis of amyloidosis, with the possible exception of cardiac transthyretin amyloidosis (ATTR) in patients without monoclonal components,[1][1] requires demonstration of tissue amyloid deposits and identification of the amyloidogeni
Autor:
Giovanni Palladini, Konen Obayashi, Giampaolo Merlini, Masayoshi Tasaki, Francesca Lavatelli, Mitsuharu Ueda, Laura Obici, Yukio Ando, Takeshi Miyamoto
Publikováno v:
Ageing research reviews. 70
Inside and outside the brain, accumulation of amyloid fibrils plays key roles in the pathogenesis of fatal age-related diseases such as Alzheimer’s and Parkinson’s diseases and wild-type transthyretin amyloidosis. Although the incidence of all am
Autor:
Toshiya Nomura, Konen Obayashi, Hiroaki Matsushita, Akihiko Ueda, Taro Yamashita, Mitsuharu Ueda, Yasuteru Inoue, Teruaki Masuda, Yohei Misumi, Akihiro Yanagisawa, Takayuki Nakamura, Takeshi Miyamoto, Masamitsu Okada, Yukio Ando, Masayoshi Tasaki
Publikováno v:
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. 28(2)
Amyloidosis is a protein-misfolding disease characterised by insoluble amyloid deposits in the extracellular space of various organs and tissues, such as the brain, heart, kidneys, and ligaments. We previously reported the frequent occurrence of amyl
Autor:
Mayumi Mizukami, Akihiko Ueda, Taro Yamashita, Teruaki Masuda, Toshiya Nomura, Yasuteru Inoue, Hirotaka Matsui, Masamitsu Okada, Kyosuke Kanenawa, Yoshinobu Hoshii, Aito Isoguchi, Tessei Torikai, Masayoshi Tasaki, Yohei Misumi, Sayaka Matsumoto, Mitsuharu Ueda, Yukimoto Tsuda, Makoto Nakamura, Yukio Ando, Konen Obayashi
Publikováno v:
The Journal of Pathology. 247:444-455
Most intractable tissue-degenerative disorders share a common pathogenic condition, so-called proteinopathy. Amyloid-related disorders are the most common proteinopathies and are characterized by amyloid fibril deposits in the brain or other organs.
Autor:
Keita Kakuda, Takashi Naka, Konen Obayashi, Shinsuke Kato, Hisae Sumi-Akamaru, Amane Yamauchi, Takuya Uehara, Masaki Eto, Hideki Mochizuki
Publikováno v:
Neuropathology. 38:11-21
Amyloidogenic protein forms amyloid aggregations at membranes leading to dysfunction of amyloid clearance and amyloidosis. Glial cells function in the clearance and degradation of amyloid β (Aβ) in the brain. This study aimed to clarify the reason