Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Kondwani C. Jambo"'
Autor:
Memory Mvula, Fatima Mtonga, Jonathan Mandolo, Chisomo Jowati, Alice Kalirani, Precious Chigamba, Edwin Lisimba, Ndaona Mitole, Marah G. Chibwana, Kondwani C. Jambo
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background Hybrid immunity provides better protection against COVID-19 than vaccination or prior natural infection alone. It induces high magnitude and broadly cross-reactive neutralising anti-Spike IgG antibodies. However, it is not clear h
Externí odkaz:
https://doaj.org/article/05866432303f451aa80e29a42395b319
Autor:
Chrispin Chaguza, Innocent Chibwe, David Chaima, Patrick Musicha, Latif Ndeketa, Watipaso Kasambara, Chimwemwe Mhango, Upendo L. Mseka, Joseph Bitilinyu-Bangoh, Bernard Mvula, Wakisa Kipandula, Patrick Bonongwe, Richard J. Munthali, Selemani Ngwira, Chikondi A. Mwendera, Akuzike Kalizang’oma, Kondwani C. Jambo, Dzinkambani Kambalame, Arox W. Kamng’ona, A. Duncan Steele, Annie Chauma-Mwale, Daniel Hungerford, Matthew Kagoli, Martin M. Nyaga, Queen Dube, Neil French, Chisomo L. Msefula, Nigel A. Cunliffe, Khuzwayo C. Jere
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Malawi experienced its deadliest Vibrio cholerae (Vc) outbreak following devastating cyclones, with >58,000 cases and >1700 deaths reported between March 2022 and May 2023. Here, we use population genomics to investigate the attributes and o
Externí odkaz:
https://doaj.org/article/6b7cbc3890c14711a1a922c4cd6b9c0a
Acute rotavirus infection is associated with the induction of circulating memory CD4+ T cell subsets
Autor:
Chikondi Malamba-Banda, Chimwemwe Mhango, Prisca Benedicto-Matambo, Jonathan J. Mandolo, End Chinyama, Orpha Kumwenda, Kayla G. Barnes, Nigel A. Cunliffe, Miren Iturriza-Gomara, Kondwani C. Jambo, Khuzwayo C. Jere
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Strong CD4+ T cell-mediated immune protection following rotavirus infection has been observed in animal models, but its relevance in humans remains unclear. Here, we characterized acute and convalescent CD4+ T cell responses in children who
Externí odkaz:
https://doaj.org/article/f54a11022a924976af074cef85e6c85f
Autor:
Deus Thindwa, Samuel Clifford, Jackie Kleynhans, Anne von Gottberg, Sibongile Walaza, Susan Meiring, Todd D. Swarthout, Elizabeth Miller, Peter McIntyre, Nick Andrews, Zahin Amin-Chowdhury, Norman Fry, Kondwani C. Jambo, Neil French, Samanta Cristine Grassi Almeida, Shamez N. Ladhani, Robert S. Heyderman, Cheryl Cohen, Maria Cristina de Cunto Brandileone, Stefan Flasche
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-8 (2023)
Vaccination against invasive pneumococcal disease is recommended for older adults but the optimal age group to target has not been determined and may vary by epidemiological setting. Here, the authors use statistical modelling to estimate the optimal
Externí odkaz:
https://doaj.org/article/46ec24eaffaa42cb9c48d6db1517712f
Autor:
Catherine Anscombe, Samantha Lissauer, Herbert Thole, Jamie Rylance, Dingase Dula, Mavis Menyere, Belson Kutambe, Charlotte van der Veer, Tamara Phiri, Ndaziona P. Banda, Kwazizira S. Mndolo, Kelvin Mponda, Chimota Phiri, Jane Mallewa, Mulinda Nyirenda, Grace Katha, Henry Mwandumba, Stephen B. Gordon, Kondwani C. Jambo, Jennifer Cornick, Nicholas Feasey, Kayla G. Barnes, Ben Morton, Philip M. Ashton, Blantyre COVID-19 Consortium
Publikováno v:
BMC Infectious Diseases, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background Compared to the abundance of clinical and genomic information available on patients hospitalised with COVID-19 disease from high-income countries, there is a paucity of data from low-income countries. Our aim was to explore the re
Externí odkaz:
https://doaj.org/article/4d8bcf03a04c4deb972cc0267183a58e
Autor:
Godfrey Bwire, Alex Riolexus Ario, Patricia Eyu, Felix Ocom, Joseph F. Wamala, Kwadwo A. Kusi, Latif Ndeketa, Kondwani C. Jambo, Rhoda K. Wanyenze, Ambrose O. Talisuna
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-23 (2022)
Abstract In December 2019, a new coronavirus, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and associated disease, coronavirus disease 2019 (COVID-19), was identified in China. This virus spread quickly and in March, 2020, it was decl
Externí odkaz:
https://doaj.org/article/5b49590358d342d8bf0990414071b740
Autor:
Upendo L. Mseka, Jonathan Mandolo, Kenneth Nyoni, Oscar Divala, Dzinkambani Kambalame, Daniel Mapemba, Moses Kamzati, Innocent Chibwe, Marc Y.R. Henrion, Kingsley Manda, Deus Thindwa, Memory Mvula, Bright Odala, Raphael Kamng'ona, Nelson Dzinza, Khuzwayo C. Jere, Nicholas Feasey, Antonia Ho, Abena S. Amoah, Melita Gordon, Todd D. Swarthout, Amelia Crampin, Robert S. Heyderman, Matthew Kagoli, Evelyn Chitsa-Banda, Collins Mitambo, John Phuka, Benson Chilima, Watipaso Kasambara, Kondwani C. Jambo, Annie Chauma-Mwale
Publikováno v:
EClinicalMedicine, Vol 56, Iss , Pp 101800- (2023)
Summary: Background: The B.1.1.529 (Omicron) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in the fourth COVID-19 pandemic wave across the southern African region, including Malawi. The seroprevalence of SARS-Co
Externí odkaz:
https://doaj.org/article/d886e6a896034979824c21646a6c6ea9
Autor:
Marah G. Chibwana, Thandeka Moyo-Gwete, Gaurav Kwatra, Jonathan Mandolo, Tandile Hermanaus, Thopisang Motlou, Nonkululeko Mzindle, Frances Ayres, Mphatso Chaponda, Godwin Tembo, Percy Mwenechanya, Ndaona Mitole, Chisomo Jassi, Raphael Kamng’ona, Louise Afran, David Mzinza, Henry C. Mwandumba, Stephen B. Gordon, Khuzwayo Jere, Shabir Madhi, Penny L. Moore, Robert S. Heyderman, Kondwani C. Jambo
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-10 (2022)
Abstract Background Binding and neutralising anti-Spike antibodies play a key role in immune defence against SARS-CoV-2 infection. Since it is known that antibodies wane with time and new immune-evasive variants are emerging, we aimed to assess the d
Externí odkaz:
https://doaj.org/article/b08b88ed1702406caaffe4634de9775e
Autor:
Marah G. Chibwana, Herbert W. Thole, Cat Anscombe, Philip M. Ashton, Edward Green, Kayla G. Barnes, Jen Cornick, Ann Turner, Desiree Witte, Sharon Nthala, Chikondi Thom, Felistas Kanyandula, Anna Ainani, Natasha Mtike, Hope Tambala, Veronica N’goma, Dorah Mwafulirwa, Erick Asima, Ben Morton, Markus Gmeiner, Zaziwe Gundah, Gift Kawalazira, Neil French, Nicholas Feasey, Robert S. Heyderman, Todd D. Swarthout, Kondwani C. Jambo
Publikováno v:
PLOS Global Public Health, Vol 3, Iss 3 (2023)
The SARS-CoV-2 Omicron variant has resulted in a high number of cases, but a relatively low incidence of severe disease and deaths, compared to the pre-Omicron variants. Therefore, we assessed the differences in symptom prevalence between Omicron and
Externí odkaz:
https://doaj.org/article/366afb93d3ba4e7091f3ab0fe452397c
Autor:
Jonathan Mandolo, Jacquline Msefula, Marc Y. R. Henrion, Comfort Brown, Brewster Moyo, Aubrey Samon, Thandeka Moyo-Gwete, Zanele Makhado, Frances Ayres, Thopisang Motlou, Nonkululeko Mzindle, Newton Kalata, Adamson S. Muula, Gaurav Kwatra, Natasha Nsamala, Andrew Likaka, Thom Mfune, Penny L. Moore, Bridon Mbaya, Neil French, Robert S. Heyderman, Todd Swarthout, Kondwani C. Jambo
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-10 (2021)
Abstract Background By August 2021, the COVID-19 pandemic has been less severe in sub-Saharan Africa than elsewhere. In Malawi, there have been three subsequent epidemic waves. We therefore aimed to describe the dynamics of SARS-CoV-2 exposure in Mal
Externí odkaz:
https://doaj.org/article/6dc34a3e1a654cbb8c7df487c319c32b