Mechanistic Investigation of the Androgen Receptor DNA-Binding Domain and Modulation via Direct Interactions with DNA Abasic Sites: Understanding the Mechanisms Involved in Castration-Resistant Prostate Cancer.

Autor: Xu S; Chemistry-School of Natural and Environmental Sciences, Newcastle University, Newcastle Upon Tyne NE1 7RU, UK.; Newcastle University Centre for Cancer, Newcastle University, Newcastle Upon Tyne NE1 7RU, UK., Kondal MD; Chemistry-School of Natural and Environmental Sciences, Newcastle University, Newcastle Upon Tyne NE1 7RU, UK., Ahmad A; Chemistry-School of Natural and Environmental Sciences, Newcastle University, Newcastle Upon Tyne NE1 7RU, UK., Zhu R; Chemistry-School of Natural and Environmental Sciences, Newcastle University, Newcastle Upon Tyne NE1 7RU, UK., Fan L; Chemistry-School of Natural and Environmental Sciences, Newcastle University, Newcastle Upon Tyne NE1 7RU, UK.; School of Engineering, Newcastle University, Newcastle Upon Tyne NE1 7RU, UK., Zaborniak P; Chemistry-School of Natural and Environmental Sciences, Newcastle University, Newcastle Upon Tyne NE1 7RU, UK., Madden KS; Chemistry-School of Natural and Environmental Sciences, Newcastle University, Newcastle Upon Tyne NE1 7RU, UK.; Translational and Clinical Research Institute, Newcastle University, Newcastle Upon Tyne NE2 4HH, UK., de Souza JV; Chemistry-School of Natural and Environmental Sciences, Newcastle University, Newcastle Upon Tyne NE1 7RU, UK., Bronowska AK; Chemistry-School of Natural and Environmental Sciences, Newcastle University, Newcastle Upon Tyne NE1 7RU, UK.; Newcastle University Centre for Cancer, Newcastle University, Newcastle Upon Tyne NE1 7RU, UK.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Jan 09; Vol. 24 (2). Date of Electronic Publication: 2023 Jan 09.