Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kondababu Rasamsetti"'
Autor:
Srikant Viswanadha, Satyanarayana Eleswarapu, Kondababu Rasamsetti, Haritha Polimati, Sridhar Veeraraghavan, Swaroop Vakkalanka
Publikováno v:
Cancer Research. 82:5493-5493
Introduction: The Poly (ADP-ribose) polymerase (PARP) family plays an important role in the regulation of transcription, apoptosis and DNA damage response. Several PARP inhibitors have been approved for the treatment of BRCA-mutated ovarian, breast a
Autor:
Srikant Viswanadha, Gayatriswaroop Merikapudi, Sridhar Veeraraghavan, Debnath Bhuniya, Kondababu Rasamsetti, Satyanarayana Eleswarapu, Swaroop Vakkalanka
Publikováno v:
Cancer Research. 81:1233-1233
Background: Poly (ADP-ribose) polymerase (PARP) activity involves synthesis of Poly-ADP ribose (PAR) polymers that recruit host DNA repair proteins leading to correction of DNA damage and maintenance of cell viability. Upon combining with DNA damagin
Autor:
Kondababu Rasamsetti, Sudhakar Kasina, Ramamohan Reddy Lekkala, Venkateswarlu Sommepalli, Vijaybaskar Lakshmikanthan, Rama Raju Gokaraju, Kiran Bhupathiraju
Publikováno v:
Cancer Research. 74:1729-1729
Introduction: First generation reversible, ATP competitive inhibitors, gefitinib and erlotinib are effective treatments for a subset of non-small cell lung cancers, in particular specific EGFR-activating mutations. However their initial efficacy is l