Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Kon-Ho Lee"'
Autor:
Hyun-Eui Park, Kyu-Min Kim, Jeong-Ih Shin, Jeong-Gyu Choi, Won-Jun An, Minh Phuong Trinh, Kyeong-Min Kang, Jung-Wan Yoo, Jung-Hyun Byun, Myung Hwan Jung, Kon-Ho Lee, Hyung-Lyun Kang, Seung Cheol Baik, Woo-Kon Lee, Min-Kyoung Shin
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-16 (2024)
Abstract Background Mycobacterium avium complex (MAC), including Mycobacterium intracellulare is a member of slow-growing mycobacteria and contributes to a substantial proportion of nontuberculous mycobacterial lung disease in humans affecting immuno
Externí odkaz:
https://doaj.org/article/ad2a315609c54dd3ad6b8e6a50cc2ccc
Publikováno v:
Biochemical and Biophysical Research Communications. 663:8-15
Publikováno v:
Microorganisms, Vol 10, Iss 1, p 193 (2022)
Cysteine proteases belonging to the falcipain (FP) family play a pivotal role in the biology of malaria parasites and have been extensively investigated as potential antimalarial drug targets. Three paralogous FP-family cysteine proteases of Plasmodi
Externí odkaz:
https://doaj.org/article/d30e238ed4b04d2daa8951125b98b6d0
Publikováno v:
Microorganisms
Cysteine proteases belonging to the falcipain (FP) family play a pivotal role in the biology of malaria parasites and have been extensively investigated as potential antimalarial drug targets. Three paralogous FP-family cysteine proteases of Plasmodi
Autor:
Amar A Telke, Ningning Zhuang, Sunil S Ghatge, Sook-Hee Lee, Asad Ali Shah, Haji Khan, Youngsoon Um, Hyun-Dong Shin, Young Ryun Chung, Kon Ho Lee, Seon-Won Kim
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65727 (2013)
Cel5A, an endoglucanase, was derived from the metagenomic library of vermicompost. The deduced amino acid sequence of Cel5A shows high sequence homology with family-5 glycoside hydrolases, which contain a single catalytic domain but no distinct cellu
Externí odkaz:
https://doaj.org/article/ae46e70a6a754314a428a97fe2a0f97a
Publikováno v:
Acta Crystallogr F Struct Biol Commun
The iron superoxide dismutase found in the pathogenic amoebaAcanthamoeba castellanii(AcFeSOD) may play essential roles in the survival of the parasite, not only by protecting it from endogenous oxidative stress but also by detoxifying oxidative killi
Autor:
Gyemin Lee, Sung Jin Yoon, Cheol Hwangbo, Killivalavan Asaithambi, In-Kyu Kim, Jung Wook Yang, Gyung Hyuck Ko, Kwang Dong Kim, Hyo Jin Kim, Minju Kim, Jong In Yook, Ki Jun Ryu, Hye Min Kim, Hyeontak Han, Jiyun Yoo, Yang Jae Kang, Jae Yong Park, Young Sool Hah, Seon Hee Kim, Young-Jun Park, Keun Seok Hong, Seung-Ho Park, Kon Ho Lee, Hee Jun Cho, Sun-Mi Park
Publikováno v:
Cancer research. 79(16)
Snail is a key regulator of epithelial–mesenchymal transition (EMT), which is a major step in tumor metastasis. Although the induction of Snail transcription precedes EMT, posttranslational regulation, especially phosphorylation of Snail, is critic
Autor:
Tong-Soo Kim, Byoung-Kuk Na, Jung-Mi Kang, Jung-Yeon Kim, Woon-Mok Sohn, Jung-Won Ju, Won-Ja Lee, Hye-Lim Ju, Jin-Young Lee, Kon Ho Lee
Publikováno v:
Protein Expression and Purification. 108:48-53
Methionine aminopeptidases (MetAPs), ubiquitous enzymes that play an important role in nascent protein maturation, have been recognized as attractive targets for the development of drugs against pathogenic protozoa including Plasmodium spp. Here, we
Autor:
Ki Hun Park, Heung Joo Yuk, Dae Wook Kim, Kon Ho Lee, Yan Wang, Yeong Hun Song, Marcus J. Curtis-Long, Kwon Seok Jeon, Ningning Zhuang
Publikováno v:
Biological and Pharmaceutical Bulletin. 37:1021-1028
Tribulus terrestris fruits are well known for their usage in pharmaceutical preparations and food supplements. The methanol extract of T. terrestris fruits showed potent inhibition against the papain-like protease (PLpro), an essential proteolylic en
Autor:
Heung Joo Yuk, Kon Ho Lee, Jung Keun Cho, Hyung Won Ryu, Dae Wook Kim, Marcus J. Curtis-Long, Ki Hun Park
Publikováno v:
Bioorganic & Medicinal Chemistry
Graphical abstract A series of geranylated flavonoids 1–12 demostrated a high inhibition against SARS-CoV pain like protease. The flavonoids 1–5 were identified as new compounds and have very rare functionality, 3,4-dihydro-2H-pyran.
SARS-Co
SARS-Co