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pro vyhledávání: '"Konč, Juraj"'
Autor:
Konč, Juraj
Syntheses of two series of 2'-sugar-modified pyrimido[4,5-b]indole nucleosides were developed. The synthetic strategy was based on functional group transformations of the 2'-hydroxy group of the 3',5'-protected ribonucleoside. The key intermediate wa
Externí odkaz:
http://www.nusl.cz/ntk/nusl-346937
Autor:
Konč, Juraj1 (AUTHOR), Sabatino, Valerio1 (AUTHOR), Jiménez‐Moreno, Ester1 (AUTHOR), Latocheski, Eloah2 (AUTHOR), Pérez, Laura Rodríguez1 (AUTHOR), Day, Jason3 (AUTHOR), Domingos, Josiel B.2 (AUTHOR), Bernardes, Gonçalo J. L.1,4 (AUTHOR) gb453@cam.ac.uk
Publikováno v:
Angewandte Chemie. 2/14/2022, Vol. 134 Issue 8, p1-6. 6p.
Autor:
Konč, Juraj1 (AUTHOR), Brown, Libby1 (AUTHOR), Whiten, Daniel R.1 (AUTHOR), Zuo, Yukun1 (AUTHOR), Ravn, Peter2,3 (AUTHOR), Klenerman, David1,4 (AUTHOR), Bernardes, Gonçalo J. L.1,5 (AUTHOR) gb453@cam.ac.uk
Publikováno v:
Angewandte Chemie. Dec2021, Vol. 133 Issue 49, p26109-26117. 9p.
Autor:
Konč, Juraj, Tichý, Michal, Pohl, Radek, Hodek, Jan, Džubák, Petr, Hajdúch, Marián, Hocek, Michal
Publikováno v:
MedChemComm
Sugar-modified pyrimido[4,5-b]indole nucleosides (2′-deoxy-2′-fluororibo-, 2′-deoxy-2′-fluoroarabino- and arabinonucleosides) were found to be low micromolar antivirals against HCV or dengue.
Three types of sugar modified pyrimido[4,5-b]
Three types of sugar modified pyrimido[4,5-b]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::29dd1a16452c01c6648a22dd3cece643
http://europepmc.org/articles/PMC6084004
http://europepmc.org/articles/PMC6084004
Autor:
Konč, Juraj
Syntheses of two series of 2'-sugar-modified pyrimido[4,5-b]indole nucleosides were developed. The synthetic strategy was based on functional group transformations of the 2'-hydroxy group of the 3',5'-protected ribonucleoside. The key intermediate wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2186::92fc39dbb95ad66a194600215fd5601c
http://www.nusl.cz/ntk/nusl-346937
http://www.nusl.cz/ntk/nusl-346937
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Autor:
Konč, Juraj
Study of glycosylation reactions of base- and sugar-modified nucleosides was performed and some of the procedures were applied for the synthesis of pyrimido[4,5-b]indole nucleosides. Only 2′-deoxy-2′-fluoro-arabinonucleoside was successfully synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2186::022c68667348e69f729d5ffe8b888084
http://www.nusl.cz/ntk/nusl-334884
http://www.nusl.cz/ntk/nusl-334884