Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Komyo ETO"'
Autor:
Ami Oguro, Taichi Fujiyama, Yasuhiro Ishihara, Chisato Kataoka, Megumi Yamamoto, Komyo Eto, Yoshihiro Komohara, Susumu Imaoka, Toshihide Sakuragi, Mayumi Tsuji, Eiji Shibata, Yaichiro Kotake, Takeshi Yamazaki
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 11, Pp 100458- (2023)
Although pregnant women’s fish consumption is beneficial for the brain development of the fetus due to the DHA in fish, seafood also contains methylmercury (MeHg), which adversely affects fetal brain development. Epidemiological studies suggest tha
Externí odkaz:
https://doaj.org/article/e92ba8be57fa4b2ea88b871630551256
Autor:
John L. O’Donoghue, Donald Harrington, Hitoshi Takahashi, Gary J. Myers, Gene E. Watson, Rubell Brewer, Komyo Eto, Tanzy Love, Grazyna Zareba, Masumi Marumoto
Publikováno v:
Neurotoxicology
Background Human exposure to mercury (Hg) is widespread and both organic and inorganic Hg are routinely found in the human brain. Millions of people are exposed to methyl Hg (MeHg) due to the consumption of fish and to inorganic Hg from dental amalga
Autor:
Satoshi Tatsumi, Shunsuke Ehara, Eiko Yoshida, Komyo Eto, Toshiyuki Kaji, Yo Shinoda, Yasuyuki Fujiwara, Tsutomu Takahashi
Publikováno v:
The Journal of Toxicological Sciences. 44:191-199
Exposure to organic mercury, especially methylmercury (MeHg), causes Minamata disease, a severe chronic neurological disorder. Minamata disease predominantly affects the central nervous system, and therefore, studies on the mechanisms of MeHg neuroto
Autor:
Toshiyuki Kaji, Komyo Eto, Yasuyuki Fujiwara, Yayoi Tsuneoka, Eiko Yoshida, Yuta Yamada, Yo Shinoda, Tsutomu Takahashi
Publikováno v:
The Journal of toxicological sciences. 46(6)
Methylmercury (MeHg), the causal substrate in Minamata disease, can lead to severe and chronic neurological disorders. The main symptom of Minamata disease is sensory impairment in the four extremities; however, the sensitivity of individual sensory
Autor:
Eriko Motomura, Tomohisa Mori, Rie Yanagisawa, Van Anh Thi Hoang, Masaaki Nakamura, Motohiro Takeya, Masaki Mogi, Komyo Eto, Megumi Yamamoto
Publikováno v:
Journal of Applied Toxicology. 39:221-230
Methylmercury (MeHg) is known to cause neurobehavioral impairment in human and experimental animals. We previously reported that MeHg (5 mg Hg/kg) induced severe neurobehavioral dysfunction in 4-week-old KK-Ay mice, although it is difficult to evalua
Publikováno v:
The Journal of Toxicological Sciences. 42:329-333
In a cerebrum damaged by methylmercury, where neuropathological lesions tend to localize along deep sulci and fissures, edematous changes in white matter have been proposed as the cause of such localization. Since hyaluronan has a high water-retentio
Autor:
Mineshi Sakamoto, José L. Domingo, Katsuyuki Murata, Ricardo Bezerra de Oliveira, Komyo Eto, Sandra Laise Ferreira Sarrazin, Hiroshi Yamazaki, Akiyoshi Kakita
Publikováno v:
Environmental Research. 152:446-453
The main purpose of the present study was to compare the blood and brain mercury (Hg) accumulation and neurological alterations in adult male and pregnant female/fetal rats following stable and episodic/bolus patterns of methylmercury (MeHg) exposure
Autor:
Toshiyuki Kaji, Yasuyuki Fujiwara, Eiko Yoshida, Yo Shinoda, Satoshi Tatsumi, Tsutomu Takahashi, Komyo Eto
Publikováno v:
The Journal of toxicological sciences. 44(8)
Methylmercury (MeHg) exposure is known to induce neurodegeneration in both the central nervous system (CNS) and peripheral nervous system (PNS). Molecular mechanisms of MeHg-induced neurotoxicity have been well investigated in the CNS, however, it re
Autor:
Megumi, Yamamoto, Eriko, Motomura, Rie, Yanagisawa, Van Anh Thi, Hoang, Masaki, Mogi, Tomohisa, Mori, Masaaki, Nakamura, Motohiro, Takeya, Komyo, Eto
Publikováno v:
Journal of applied toxicology : JAT. 39(2)
Methylmercury (MeHg) is known to cause neurobehavioral impairment in human and experimental animals. We previously reported that MeHg (5 mg Hg/kg) induced severe neurobehavioral dysfunction in 4-week-old KK-Ay mice, although it is difficult to evalua
Autor:
Eriko Motomura, Megumi Yamamoto, Rie Yanagisawa, Mineshi Sakamoto, Motohiro Takeya, Komyo Eto, Masaaki Nakamura
Publikováno v:
Journal of Applied Toxicology. 34:914-923
We examined the toxic effects of methylmercury (MeHg) in KK-Ay type 2 diabetic mice to clarify how metabolic changes associated with type 2 diabetes mellitus affect MeHg toxicity. MeHg (5 mg Hg kg –1day–1 p.o.) was given to 4-week-old male KK-Ay