Interferon β-1b-neutralizing antibodies 5 years after clinically isolated syndrome

Autor: Hartung, Hp, Strasser Fuchs, S, Berger, T, Vass, K, Sindic, C, Dubois, B, Dive, D, Debruyne, J, Metz, L, Rice, G, Duquette, P, Lapierre, Y, Freedman, M, Traboulsee, A, O'Connor, P, Stourac, P, Taláb, R, Zapletalová, O, Kováøová, I, Medová, E, Fiedler, J, Frederiksen, J, Brochet, B, Moreau, T, Vermersch, P, Pelletier, J, Edan, G, Clanet, M, Clavelou, P, Lebrun Frenay, C, Gout, O, Kallela, M, Pirttilä, T, Ruutiainen, J, Koivisto, K, Reunanen, M, Elovaara, I, Villringer, A, Altenkirch, H, Wessel, K, Steinke, W, Kölmel, H, Oschmann, P, Diem, R, Dressel, A, Hoffmann, F, Baum, K, Jung, S, Petereit, Hf, Reske, D, Sailer, M, Köhler, J, Sommer, N, Hohlfeld, R, Henn, Kh, Steinbrecher, A, Tumani, H, Gold, R, Rieckmann, P, Komoly, R, Gács, G, Jakab, G, Csiba, L, Vécsei, L, Miller, A, Karussis, D, Chapman, J, Ghezzi, A, Comi, G, Gallo, Paolo, Cosi, V, Durelli, L, Anten, B, Visser, L, Myhr, Km, Szczudlik, A, Selmaj, K, Stelmasiak, Z, Podemski, R, Maciejek, Z, Cunha, L, Sega Jazbec, S, Montalba, X, Arbizu, T, Saiz, A, Bárcena, J, Arroyo, R, Fernández, O, Izquierdo, G, Casanova, B, Lycke, J, Kappos, L, Mattle, H, Beer, K, Coleman, R, Chataway, J, O'Riordan, J, Howell, S. .

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3657::784f0f348b465b09ff1d0d230995a748
http://hdl.handle.net/11577/2496642

Long-term effect of early treatment with interferon beta-1b after a first clinical event suggestive of multiple sclerosis: 5-year active treatment extension of the phase 3 BENEFIT trial

Autor: Strasser Fuchs, S, Berger, T, Vass, K, Sindic, C, Dubois, B, Dive, D, Debruyne, J, Metz, L, Rice, G, Duquette, P, Lapierre, Y, Freedman, M, Traboulsee, A, O'Connor, P, Stourac, P, Taláb, R, Zapletalová, O, Kovárová, I, Medová, E, Fiedler, J, Frederiksen, J, Brochet, B, Moreau, T, Vermersch, P, Pelletier, J, Edan, G, Clanet, M, Clavelou, P, Lebrun Frenay, C, Gout, O, Kallela, M, Pirttilä, T, Ruutiainen, J, Koivisto, K, Reunanen, M, Elovaara, I, Villringer, A, Altenkirch, H, Wessel, K, Hartung, Hp, Steinke, W, Kölmel, H, Oschmann, P, Diem, R, Dressel, A, Hoff, F, Baum, K, Jung, S, Felicitas Petereit, H, Reske, D, Sailer, M, Köhler, J, Sommer, N, Hohlfeld, R, Henn, Kh, Steinbrecher, A, Tumani, H, Gold, R, Rieckmann, P, Komoly, R, Gács, G, Jakab, G, Csiba, L, Vécsei, L, Miller, A, Karussis, D, Chapman, J, Ghezzi, A, Comi, G, Gallo, Paolo, Cosi, V, Durelli, L, Anten, B, Visser, L, Myhr, Km, Szczudlik, A, Selmaj, K, Stelmasiak, Z, Podemski, R, Maciejek, Z, Cunha, L, Sega Jazbec, S, Montalbán, X, Arbizu, T, Saiz, A, Bárcena, J, Arroyo, R, Fernández, O, Izquierdo, G, Casanova, B, Lycke, J, Kappos, L, Mattle, H, Beer, K, Coleman, R, Chataway, J, O'Riordan, J, Howell, S, Miller, Dh, Polman, Ch, Bauer, L, Ghazi, M, Pohl, C, Sandbrink, R, Barkhof, F, Uitdehaag, B, de Vera, A, Wu, S, Radü, Ew, Mcfarland, Hf, Kesselring, J, Petkau, Aj, Toyka, K. V.

Publikováno v: Lancet Neurology, 8(11), 987-997. Lancet Publishing Group
Kappos, L, Freedman, M S, Polman, C H, Edan, G, Hartung, H P, Miller, D, Montalban, X, Barkhof, F, Radu, E W, Metzig, C, Bauer, L, Lanius, V, Sandbrink, R & Pohl, C 2009, ' Long-term effect of early treatment with interferon beta-1b after a first clinical event suggestive of multiple sclerosis: 5-year active treatment extension of the phase 3 BENEFIT trial ', Lancet Neurology, vol. 8, no. 11, pp. 987-997 . https://doi.org/10.1016/S1474-4422(09)70237-6
The Lancet Neurology, Vol. 8, no.11, p. 987-97 (2009)

BACKGROUND: The Betaferon/Betaseron in newly emerging multiple sclerosis for initial treatment (BENEFIT) trial investigated the effect of treatment with interferon beta-1b after a clinically isolated syndrome. The 5-year active treatment extension co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32de5c13d4271bf7c0708befa9bfb69e
https://lirias.kuleuven.be/handle/123456789/257768

Treatment with interferon beta-1b delays conversion to clinically definite and McDonald MS in patients with clinically isolated syndromes

Autor: Kappos, L, Polman, Ch, Freedman, Ms, BENEFIT Study G. r. o. u. p. Principal investigators—Austria: S. Strasser Fuchs, Graz, T. Berger, Innsbruck, Vass, K., Sindic, V. i. e. n. n. a. Belgium: C., Brussels, B. Dubois, Leuven, D. Dive, Liège, Debruyne, J., Metz, G. h. e. n. t. Canada: L., Calgary, G. Rice, London, Duquette, P., Lapierre, Y., Montreal, M. Freedman, Ottawa, A. Traboulsee, Vancouver, O’Connor, P., Štourač, T. o. r. o. n. t. o. Czech Republic: P., Brno, R. Taláb, Hradec Kralove, O. Zapletalová, Ostrava, Kovářová, I., Medová, E., Prague, Fiedler, J., Frederiksen, P. l. z. e. n. Denmark: J., Brochet, G. l. o. s. t. r. u. p. France: B., Bordeaux, T. Moreau, Dijon, P. Vermersch, Lille, J. Pelletier, Marseille, G. Edan, Rennes, M. Clanet, Toulouse, P. Clavelou, Clermont Ferrand, C. Lebrun Frenay, Nice, Gout, O., Kallela, P. a. r. i. s. Finland: M., Helsinki, T. Pirttilä, Kuopio, J. Ruutiainen, Turku, K. Koivisto, Seinäjoki, M. Reunanen, Oulu, Elovaara, I., Villringer, T. a. m. p. e. r. e. Germany: A., Altenkirch, H., Berlin, K. Wessel, Braunschweig, Hartung, H. P., Steinke, W., Düsseldorf, H. Kölmel, Erfurt, P. Oschmann, Giessen, R. Diem, Göttingen, A. Dressel, Greifswald, F. Hoffmann, Halle/saale, K. Baum, Hennigsdorf, S. Jung, Homburg/saar, Petereit, H., Reske, D., Cologne, M. Sailer, Magdeburg, J. Köhler, Mainz, N. Sommer, Marburg, R. Hohlfeld, Munich, K. H. Henn, Offenbach, A. Steinbrecher, Regensburg, H. Tumani, Ulm, Gold, R., Rieckmann, P., Würzburg, Komoly, R., Gács, G., Jakab, G., Budapest, L. Csiba, Debrecen, Vécsei, L., Miller, S. z. e. g. e. d. Israel: A., Haifa, D. Karussis, Jerusalem, Chapman, J., Ghezzi, Tel H. a. s. h. o. m. e. r. Italy: A., Gallarate, G. Comi, Milan, Gallo, Paolo, V. Cosi, Pavia, Durelli, L., Anten, T. u. r. i. n. Netherlands: B., Sittard, Visser, L., Myhr, T. i. l. b. u. r. g. Norway: K. M., Szczudlik, B. e. r. g. e. n. Poland: A., Kraków, K. Selmaj, Łódź, Z. Stelmasiak, Lublin, R. Podemski, Wrocław, Maciejek, Z., Cunha, B. y. d. g. o. s. z. c. z. Portugal: L., Sega Jazbec, C. o. i. m. b. r. a. Slovenia: S., Montalbán, L. j. u. b. l. j. a. n. a. Spain: X., Arbizu, T., Saiz, A., Barcelona, J. Bárcena, Barakaldo, R. Arroyo, Madrid, O. Fernández, Málaga, G. Izquierdo, Seville, Casanova, B., Lycke, V. a. l. e. n. c. i. a. Sweden: J., Kappos, M. ö. l. n. d. a. l. Switzerland: L., Basel, H. Mattle, Bern, Beer, K., Coleman, St G. a. l. l. e. n. UK: R., Aberdeen, J. Chataway, London, J. O’Riordan, Dundee, S. Howell, Sheffield

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3657::01593441ff12262f85be1391c6b4a52d
http://hdl.handle.net/11577/152033