Human genes with codon usage bias similar to that of the nonstructural protein 1 gene of influenza A viruses are conjointly involved in the infectious pathogenesis of influenza A viruses

Autor: Komi Nambou, Manawa Anakpa, Yin Selina Tong

Publikováno v: Genetica. 150:97-115

Molecular mechanisms of the non-structural protein 1 (NS1) in influenza A-induced pathological changes remain ambiguous. This study explored the pathogenesis of human infection by influenza A viruses (IAVs) through identifying human genes with codon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0dd8c9a8042b6a4e1f246145ebd752
https://doi.org/10.1007/s10709-022-00155-9

Weighted gene co-expression network analysis and drug-gene interaction bioinformatics uncover key genes associated with various presentations of malaria infection in African children and major drug candidates

Autor: Komi Nambou, Xiaoling Nie, Yin Tong, Manawa Anakpa

Publikováno v: Infection, Genetics and Evolution

Malaria is a fatal parasitic disease with unelucidated pathogenetic mechanism. Herein, we aimed to uncover genes associated with different clinical aspects of malaria based on the GSE1124 dataset that is publicly accessible by using WGCNA. We obtaine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce5e81c442982a3cd451444f088ef04e
https://doi.org/10.1016/j.meegid.2021.104723

Improvement of Ansamitocin P-3 Production by Actinosynnema mirum with Fructose as the Sole Carbon Source

Autor: Qiang Hua, Komi Nambou, Tinglan Li, Tadayuki Imanaka, Fengxian Hu, Liu-Jing Wei, Yuxiang Fan

Publikováno v: Applied Biochemistry and Biotechnology. 175:2845-2856

Ansamitocin P-3 (AP-3) is an active and potent anti-tumor maytansinoid, which is usually produced by Actinosynnema spp. In this study, the effects of different carbon sources on biomass and AP-3 production by Actinosynnema mirum were investigated. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1fa47df48f2c567dbcba36ff567eea8
https://doi.org/10.1007/s12010-014-1445-6

Evaluation of metabolome sample preparation methods regarding leakage reduction for the oleaginous yeast Yarrowia lipolytica

Autor: Jun Chen, Tadayuki Imanaka, Komi Nambou, Chen Zhao, Liu-Jing Wei, Qiang Hua

Publikováno v: Biochemical Engineering Journal. 82:63-70

Yarrowia lipolytica is the well-known oleaginous yeast able to accumulate amounts of lipids and a variety of high value products. The knowledge of its intracellular metabolites concentrations, which are directly linked to the sample preparation of co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9179c708c722570cd0a9b913dc56a00e
https://doi.org/10.1016/j.bej.2013.11.004

Flux balance analysis inspired bioprocess upgrading for lycopene production by a metabolically engineered strain of Yarrowia lipolytica

Autor: Xing-Xing Jian, Xin-Kai Zhang, Jiajia Lou, Catherine Madzak, Liu-Jing Wei, Komi Nambou, Qiang Hua

Publikováno v: Metabolites
Metabolites, MDPI, 2015, 5 (4), pp.794-813. ⟨10.3390/metabo5040794⟩
Metabolites 4 (5), 794-813. (2015)
Metabolites, Vol 5, Iss 4, Pp 794-813 (2015)
Volume 5
Issue 4
Pages 794-813

International audience; Genome-scale metabolic models embody a significant advantage of systems biology since their applications as metabolic flux simulation models enable predictions for the production of industrially-interesting metabolites. The bi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc37f3f262b65fa5126416e65a979b37
https://hal.inrae.fr/hal-02640872/file/Metabolites2015_lycopeneYl_1.pdf