Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Komal M. Nayak"'
Culture Associated DNA Methylation Changes Impact on Cellular Function of Human Intestinal Organoids
Autor:
Rachel D Edgar, Francesca Perrone, April R Foster, Felicity Payne, Sophia Lewis, Komal M Nayak, Judith Kraiczy, Aurélie Cenier, Franco Torrente, Camilla Salvestrini, Robert Heuschkel, Kai O Hensel, Rebecca Harris, D. Leanne Jones, Daniel R Zerbino, Matthias Zilbauer
Background & AimsHuman intestinal epithelial organoids (IEO) are a powerful tool to model major aspects of intestinal development, health and diseases, as patient derived cultures retain many features found in-vivo. A necessary aspect of the organoid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c70d852eae9f9e5b1e0975ac83948df8
https://doi.org/10.1101/2022.04.25.489354
https://doi.org/10.1101/2022.04.25.489354
Culture-Associated DNA Methylation Changes Impact on Cellular Function of Human Intestinal Organoids
Autor:
Rachel D. Edgar, Francesca Perrone, April R. Foster, Felicity Payne, Sophia Lewis, Komal M. Nayak, Judith Kraiczy, Aurélie Cenier, Franco Torrente, Camilla Salvestrini, Robert Heuschkel, Kai O. Hensel, Rebecca Harris, D. Leanne Jones, Daniel R. Zerbino, Matthias Zilbauer
Publikováno v:
Cellular and molecular gastroenterology and hepatology. 14(6)
BACKGROUND & AIMS: Human intestinal epithelial organoids (IEOs) are a powerful tool to model major aspects of intestinal development, health, and diseases because patient-derived cultures retain many features found in vivo. A necessary aspect of the
Autor:
Andreas C Jenke, Jan Postberg, Timothy Raine, Komal M Nayak, Malte Molitor, Stefan Wirth, Arthur Kaser, Miles Parkes, Robert B Heuschkel, Valerie Orth, Matthias Zilbauer
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55636 (2013)
Epigenetic signatures are highly cell type specific. Separation of distinct cell populations is therefore desirable for all epigenetic studies. However, to date little information is available on whether separation protocols might influence epigeneti
Externí odkaz:
https://doaj.org/article/b796f1f48cf042209bd93e9484628a09
Publikováno v:
Gut
Autor:
Judith, Kraiczy, Komal M, Nayak, Kate J, Howell, Alexander, Ross, Jessica, Forbester, Camilla, Salvestrini, Roxana, Mustata, Sally, Perkins, Amanda, Andersson-Rolf, Esther, Leenen, Anke, Liebert, Ludovic, Vallier, Philip C, Rosenstiel, Oliver, Stegle, Gordon, Dougan, Robert, Heuschkel, Bon-Kyoung, Koo, Matthias, Zilbauer
Publikováno v:
Gut. 68(1)
Human intestinal epithelial organoids (IEOs) are increasingly being recognised as a highly promising translational research tool. However, our understanding of their epigenetic molecular characteristics and behaviour in culture remains limited.We per