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pro vyhledávání: '"Kolette M. Flood"'
Autor:
Jay S. Trivedi, Stephen P. Arneric, Sherry Carroll, Steven L. Krill, Yihong Qiu, Kennan C. Marsh, Kolette M. Flood
Publikováno v:
International Journal of Pharmaceutics. 157:43-52
ABT-089 is a potent cholinergic channel modulator under investigation for treatment of cognitive disorders. It is a highly water soluble compound with a short elimination half-life of 1.7 h in dogs. Hydrophilic and hydrophobic matrix systems were des