Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kolby L. White"'
Publikováno v:
J Org Chem
We describe a palladium catalyzed C7-acetoxylation of indolines with a range of amide directing groups. While a variety of substituents are tolerated on the indoline-core and the N1-acyl group, the acetoxylation is most sensitive to the C2- and C6-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ba9a17a030e2c5d8aa4deda58dd0639
https://doi.org/10.1021/acs.joc.1c02811
https://doi.org/10.1021/acs.joc.1c02811
Autor:
Michael B. Rooney, Benjamin P. MacLeod, Ryan Oldford, Zachary J. Thompson, Kolby L. White, Justin Tungjunyatham, Brian J. Stankiewicz, Curtis P. Berlinguette
Publikováno v:
Digital Discovery. 1:382-389
This self-driving laboratory combines a robot for preparing and testing adhesive bonds with an optimizer to rapidly improve adhesive formulations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc1ce92f191b3a9ce372aca6bf0f1110
https://doi.org/10.1039/d2dd00029f
https://doi.org/10.1039/d2dd00029f
Publikováno v:
Organic Letters. 20:3647-3650
The first enantioselective total synthesis of (-)-vallesine via a strategy that features a late-stage regioselective C17-oxidation followed by a highly stereoselective transannular cyclization is reported. The versatility of this approach is highligh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::448dc5e38745dbd59a5496d7f201e9f0
https://doi.org/10.1021/acs.orglett.8b01428
https://doi.org/10.1021/acs.orglett.8b01428
Publikováno v:
PMC
The first enantioselective total synthesis of (−)-deoxoapodine is described. Our synthesis of this hexacyclic aspidosperma alkaloid includes an efficient molybdenum-catalyzed enantioselective ring-closing metathesis reaction for the desymmetrizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::238390167f7c613405517604e1400cad
https://doi.org/10.1002/ange.201708088
https://doi.org/10.1002/ange.201708088
Autor:
Kolby L. White, Mohammad Movassaghi
Publikováno v:
Journal of the American Chemical Society. 138:11383-11389
We report the first total syntheses of (+)-haplocidine and its N1-amide congener (+)-haplocine. Our concise synthesis of these alkaloids required the development of a late-stage and highly selective C-H oxidation of complex aspidosperma alkaloid deri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8de31be1d4984167ad3d18e41e88fb4a
https://doi.org/10.1021/jacs.6b07623
https://doi.org/10.1021/jacs.6b07623
Publikováno v:
The Journal of organic chemistry. 80(15)
The first mechanistic investigation of electrophilic amide activation of α,α-disubstituted tertiary lactams and the direct observation of key intermediates by in situ FTIR, (1)H, (13)C, and (19)F NMR in our interrupted Bischler-Napieralski-based sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c2968dc1f9e70764c4a7abc5bb8f6aa
https://pubmed.ncbi.nlm.nih.gov/26166404
https://pubmed.ncbi.nlm.nih.gov/26166404
Publikováno v:
Chemical Science. 3:1205
A Lewis base-promoted addition of α-silyl silylethers to primary halides has been developed. This new carbon–carbon sp3–sp3 bond-forming process accesses an unconventional reactivity pattern (d1 synthon) from easily accessible precursors. The st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bdb40bb565e16ccd20391ff479db246
https://doi.org/10.1039/c2sc00581f
https://doi.org/10.1039/c2sc00581f