Dose-Dependent Acute Effects of Everolimus Administration on Immunological, Neuroendocrine and Psychological Parameters in Healthy Men

Autor: Hörbelt, Tina, Kahl, Anna Lena, Kolbe, Frederike, Hetze, Susann, Wilde, Benjamin, Witzke, Oliver, Schedlowski, Manfred

The rapamycin analogue everolimus (EVR) is a potent inhibitor of the mammalian target of rapamycin (mTOR) and clinically used to prevent allograft rejections as well as tumor growth. The pharmacokinetic and immunosuppressive efficacy of EVR have been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=unidue___bib::aa4430c994b96d7e9dc7c3b93b72c108
https://www.ncbi.nlm.nih.gov/pubmed/32475067

Dose-Dependent Acute Effects of Everolimus Administration on Immunological, Neuroendocrine and Psychological Parameters in Healthy Men.

Autor: Hörbelt T; Institute of Medical Psychology and Behavioral Immunobiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Kahl AL; Institute of Medical Psychology and Behavioral Immunobiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Kolbe F; Institute of Medical Psychology and Behavioral Immunobiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Hetze S; Clinic of Neurosurgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Wilde B; Department of Nephrology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Witzke O; Department of Nephrology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; Department of Infectious Diseases, West German Centre of Infectious Diseases, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Schedlowski M; Institute of Medical Psychology and Behavioral Immunobiology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Karolinska Institutet, Stockholm, Sweden.

Publikováno v: Clinical and translational science [Clin Transl Sci] 2020 Nov; Vol. 13 (6), pp. 1251-1259. Date of Electronic Publication: 2020 May 31.