The binding of the small heat-shock protein α B-crystallin to fibrils of α -synuclein is driven by entropic forces

Autor: Scheidt, Tom, Carozza, Jacqueline A., Kolbe, Carl C., Aprile, Francesco A., Tkachenko, Olga, Bellaiche, Mathias M. J., Meisl, Georg, Peter, Quentin A. E., Herling, Therese W., Ness, Samuel, Castellana-Cruz, Marta, Benesch, Justin L. P., Vendruscolo, Michele, Dobson, Christopher M., Arosio, Paolo, Knowles, Tuomas P. J.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2021 Sep . 118(38), 1-8.

Externí odkaz: https://www.jstor.org/stable/27075648

The binding of the small heat-shock protein αB-crystallin to fibrils of α-synuclein is driven by entropic forces.

Autor: Scheidt, Tom, Carozza, Jacqueline A., Kolbe, Carl C., Aprile, Francesco A., Tkachenko, Olga, Bellaiche, Mathias M. J., Meisl, Georg, Peter, Quentin A. E., Herling, Therese W., Ness, Samuel, Castellana-Cruz, Marta, Benesch, Justin L. P., Vendruscolo, Michele, Dobson, Christopher M., Arosio, Paolo, Knowles, Tuomas P. J.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America; 9/21/2021, Vol. 118 Issue 38, p1-8, 8p

The binding of the small heat-shock protein αB-crystallin to fibrils of α-synuclein is driven by entropic forces

Autor: Scheidt, Tom, Carozza, Jacqueline A, Kolbe, Carl C, Aprile, Francesco A, Tkachenko, Olga, Bellaiche, Mathias MJ, Meisl, Georg, Peter, Quentin AE, Herling, Therese W, Ness, Samuel, Castellana-Cruz, Marta, Benesch, Justin LP, Vendruscolo, Michele, Dobson, Christopher M, Arosio, Paolo, Knowles, Tuomas PJ

Molecular chaperones are key components of the cellular proteostasis network whose role includes the suppression of the formation and proliferation of pathogenic aggregates associated with neurodegenerative diseases. The molecular principles that all

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6c81ea2a0656d0f9dd29c2eaf1e90a6a