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Bispecific killer cell engagers employing species cross-reactive NKG2D binders redirect human and murine lymphocytes to ErbB2/HER2-positive malignancies.

Autor: Pfeifer Serrahima J; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.; Frankfurt Cancer Institute, Goethe University, Frankfurt, Germany., Schoenfeld K; Institute for Organic Chemistry and Biochemistry, Technical University of Darmstadt, Darmstadt, Germany., Kühnel I; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany., Harwardt J; Institute for Organic Chemistry and Biochemistry, Technical University of Darmstadt, Darmstadt, Germany., Macarrón Palacios A; Institute for Organic Chemistry and Biochemistry, Technical University of Darmstadt, Darmstadt, Germany., Prüfer M; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany., Kolaric M; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany., Oberoi P; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany., Kolmar H; Institute for Organic Chemistry and Biochemistry, Technical University of Darmstadt, Darmstadt, Germany.; Centre for Synthetic Biology, Technical University of Darmstadt, Darmstadt, Germany., Wels WS; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.; Frankfurt Cancer Institute, Goethe University, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.

Publikováno v: Frontiers in immunology [Front Immunol] 2024 Aug 29; Vol. 15, pp. 1457887. Date of Electronic Publication: 2024 Aug 29 (Print Publication: 2024).