Zobrazeno 1 - 10 of 21 pro vyhledávání: '"Kolade Olatubosun Faloye"'
1
Akademický článek
In vitro and in silico studies reveal antidiabetic properties of arylbenzofurans from the root bark of Morus mesozygia Stapf
Autor: Katherine Olabanjo Olufolabo, Kai Lüersen, Samuel Ayoolu Oguntimehin, Vaderament-A. Nchiozem-Ngnitedem, Emmanuel Ayodeji Agbebi, Kolade Olatubosun Faloye, Divinah Kwamboka Nyamboki, Gerald Rimbach, Josphat Clement Matasyoh, Bernd Schmidt, Jones Olanrewaju Moody
Publikováno v: Frontiers in Pharmacology, Vol 15 (2024)
Diabetes remains an important disease worldwide with about 500 million patients globally. In tropical Africa, Morus mesozygia is traditionally used in the treatment of diabetes. Biological and phytochemical investigation of the root bark extracts of
Externí odkaz: https://doaj.org/article/13e705510abf4b93b741d3f9ccfea557
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2
Akademický článek
Elucidating the monoamine oxidase B inhibitory effect of kaurene diterpenoids from Xylopia aethiopica: An in silico approach.
Autor: Funmilayo Gladys Famuyiwa, Rajesh B Patil, Samson Oluwaseyi Famuyiwa, Uduak Ime Olayemi, Esther Aina Olanudun, Bhoomendra A Bhongade, Jaiprakash N Sangshetti, Esther Oluwatosin Shalom, Suvarna N Vakare, Mohammed Sakib Musa, Abu Tayab Moin, Mohammad Helal Uddin, Kolade Olatubosun Faloye
Publikováno v: PLoS ONE, Vol 19, Iss 11, p e0308021 (2024)
Parkinson disease is a neurogenerative disease common in adults and results in different kinds of memory dysfuntions. This study evaluated the monoamine oxidase B (MAO-B) inhibitory potential of kaurane diterpenoids previously isolated from Xylopia a
Externí odkaz: https://doaj.org/article/20de9b487eb949fa9c77870e175918c1
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3
Akademický článek
4′-O-galloy-3,3′-di-O-methylellargic acid 4-O-xylopyranoside; a potential anti-diabetic agent
Autor: Samson Oluwaseyi Famuyiwa, Kolade Olatubosun Faloye, Marcus Durojaiye Ayoola, Emmanuel Gabriel Fakola, Derek Tantoh Ndinteh
Publikováno v: Results in Chemistry, Vol 4, Iss , Pp 100644- (2022)
The search for phytochemicals for their pharmacological effects cannot be over emphasized. 4′-O-galloy-3,3′-di-O-methylellargic acid 4-O-xylopyranoside (GEP) was isolated from the stem bark of Terminalia superba. The structural elucidation was ca
Externí odkaz: https://doaj.org/article/4eeb046110284e6cab8e0e9da0bfceb5
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4
Akademický článek
Computational Assessment of Xanthones from African Medicinal Plants as Aldose Reductase Inhibitors
Autor: Onikepe Deborah Owoseeni, Rajesh B. Patil, Prajakta M. Phage, Ruth Mosunmola Ogboye, Marcus Durojaye Ayoola, Samson Oluwaseyi Famuyiwa, Felix Olusegun Gboyero, Derek Tantoh Ndinteh, Kolade Olatubosun Faloye
Publikováno v: Computation, Vol 10, Iss 9, p 146 (2022)
Diabetes mellitus is a life-threatening non-communicable disease that affects all age groups. Despite the increased attention it has received in recent years, the number of diabetic patients has grown exponentially. These increased cases are attribut
Externí odkaz: https://doaj.org/article/0bcfcd5e9a6b4006bb0055d830f143b2
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5
Antioxidant potentials of the pod extract of Caesalpinia pulcherrima Swartz (Fabeace) and the theoretical evaluation of the antioxidant property of the isolated compounds
Autor: null Kolade Olatubosun FALOYE, null Samson Oluwaseyi FAMUYIWA, null Kemi Feyisayo AKINWUNMI, null Charlotte Mungho. TATA, null Marcus Durojaiye AYOOLA, null Emmanuel Gabriel FAKOLA, null Olawale Folorunso AKINYELE, null Derek Tantoh NDINTEH
Publikováno v: International Journal of Science and Research Archive. 7:456-464
Various diseases associated with oxidative stress have necessitated the need to investigate plants for antioxidant agents. This study aims to investigate the antioxidant potential of the extract and fractions of C. pulcherrima and estimate the quantu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7aa5bf249792c86ed6f8a21d6d820490
https://doi.org/10.30574/ijsra.2022.7.1.0183
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6
Akademický článek
Elucidating the Glucokinase Activating Potentials of Naturally Occurring Prenylated Flavonoids: An Explicit Computational Approach
Autor: Kolade Olatubosun Faloye, Boris Davy Bekono, Emmanuel Gabriel Fakola, Marcus Durojaye Ayoola, Oyenike Idayat Bello, Oluwabukunmi Grace Olajubutu, Onikepe Deborah Owoseeni, Shafi Mahmud, Mohammed Alqarni, Ahmed Abdullah Al Awadh, Mohammed Merae Alshahrani, Ahmad J. Obaidullah
Publikováno v: Molecules, Vol 26, Iss 23, p 7211 (2021)
Glucokinase activators are considered as new therapeutic arsenals that bind to the allosteric activator sites of glucokinase enzymes, thereby maximizing its catalytic rate and increasing its affinity to glucose. This study was designed to identify po
Externí odkaz: https://doaj.org/article/44c9b760aa604228bbc394f60fc448f7
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7
In silico identification of Fructose-1,6-Biphosphatase Inhibitory Potentials of Xanthones Isolated from African Medicinal Plants: An Integrated Computational Approach
Autor: Kolade Olatubosun Faloye, Rajesh B. Patil, Onikepe Deborah Owoseeni, Prajakta M. Phage, Samson Oluwaseyi. Famuyiwa, Felix Olusegun Gboyero, Glory Mayokun Arowojolu
Publikováno v: Letters in Drug Design & Discovery. 20
Background: Type 2 diabetes mellitus continues to pose a threat to the existence of the human race. The increasing number of diabetic subjects can be effectively controlled by targeting enzymes responsible for high blood glucose levels. Xanthones are
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::75b7f088104170d51746755b7cea2dee
https://doi.org/10.2174/1570180820666230417124235
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9
Isolation and Characterization of Two New Polyphenols from the Anti-Diabetic Fraction of Pod Extract of Caesalpinia pulcherrima Swartz
Autor: Kolade Olatubosun Faloye, Derek Tahton Ndinteh, Marcus Durojaye Ayoola, Samson O. Famuyiwa
Publikováno v: European Journal of Medicinal Plants. :48-56
This study was planned and executed to validate the anti-diabetic ethno-medicinal claim of Caesalpinia pulcherrima (Fabaceae) pods and the isolation of potential chemical compounds responsible for the activity.The anti-diabetic activity of the extrac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a0149dbb2178e179d13bd40a456e3a30
https://doi.org/10.9734/ejmp/2020/v31i2030356
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10
Elucidating the Glucokinase Activating Potentials of Naturally Occurring Prenylated Flavonoids: An Explicit Computational Approach
Autor: Mohammed H. Alqarni, Shafi Mahmud, Boris Davy Bekono, Oyenike Idayat Bello, Kolade Olatubosun Faloye, Onikepe Deborah Owoseeni, Emmanuel Gabriel Fakola, Mohammed Merae Alshahrani, Oluwabukunmi Grace Olajubutu, Marcus Durojaye Ayoola, Ahmad J. Obaidullah, Ahmed Abdullah Al Awadh
Publikováno v: Molecules, Vol 26, Iss 7211, p 7211 (2021)
Molecules
Molecules; Volume 26; Issue 23; Pages: 7211
Glucokinase activators are considered as new therapeutic arsenals that bind to the allosteric activator sites of glucokinase enzymes, thereby maximizing its catalytic rate and increasing its affinity to glucose. This study was designed to identify po
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac23463f031f2bfdcd0ca9ccc784b462
https://www.mdpi.com/1420-3049/26/23/7211
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