The interplay of poorly soluble drugs in dissolution from amorphous solid dispersions

Autor: Kokott, Marcel, Breitkreutz, Jörg, Wiedey, Raphael

Publikováno v: In International Journal of Pharmaceutics: X June 2024 7

Development of a multiparticulate drug delivery system for in situ amorphisation

Autor: Holm, Tobias Palle, Kokott, Marcel, Knopp, Matthias Manne, Boyd, Ben J., Berthelsen, Ragna, Quodbach, Julian, Löbmann, Korbinian, Afd Pharmaceutics, Pharmaceutics

Publikováno v: European Journal of Pharmaceutics and Biopharmaceutics, 180, 170. Elsevier
Holm, T P, Kokott, M, Knopp, M M, Boyd, B J, Berthelsen, R, Quodbach, J & Löbmann, K 2022, ' Development of a multiparticulate drug delivery system for in situ amorphisation ', European Journal of Pharmaceutics and Biopharmaceutics, vol. 180, pp. 170-180 . https://doi.org/10.1016/j.ejpb.2022.09.021

In the current study, the concept of multiparticulate drug delivery systems (MDDS) was applied to tablets intended for the amorphisation of supersaturated granular ASDs in situ, i.e. amorphisation within the final dosage form by microwave irradiation

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https://dspace.library.uu.nl/handle/1874/425537

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Development of a multiparticulate drug delivery system for in situ amorphisation.

Autor: Holm TP; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Kokott M; Institut für Pharmazeutische Technologie und Biopharmazie, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany., Knopp MM; Bioneer:FARMA, Department of Pharmacy, Copenhagen, Denmark., Boyd BJ; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Berthelsen R; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Quodbach J; Institut für Pharmazeutische Technologie und Biopharmazie, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands., Löbmann K; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address: korbinian.loebmann@sund.ku.dk.

Publikováno v: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V [Eur J Pharm Biopharm] 2022 Nov; Vol. 180, pp. 170-180. Date of Electronic Publication: 2022 Oct 01.