Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kokilavani Sivaraman"'
Autor:
Kokilavani Sivaraman, Paco Pino, Guillaume Raussin, Stephanie Anchisi, Charles Metayer, Nicolas Dagany, Julia Held, Sabine Wrenger, Tobias Welte, Maria J. Wurm, Florian M. Wurm, Beata Olejnicka, Sabina Janciauskiene
Publikováno v:
Microorganisms, Vol 11, Iss 11, p 2683 (2023)
Intracellular lipid droplets (LDs) can accumulate in response to inflammation, metabolic stresses, and other physiological/pathological processes. Herein, we investigated whether spike proteins of SARS-CoV-2 induce LDs in human peripheral blood monon
Externí odkaz:
https://doaj.org/article/db2413774549499d9f185926ebfc3649
Autor:
Tomoyuki Nakagiri, Sabine Wrenger, Kokilavani Sivaraman, Fabio Ius, Tobias Goecke, Patrick Zardo, Veronika Grau, Tobias Welte, Axel Haverich, Ann-Kathrin Knöfel, Sabina Janciauskiene
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-12 (2021)
Abstract Background α1-Antitrypsin (AAT) is an acute phase glycoprotein, a multifunctional protein with proteinase inhibitory, anti-inflammatory and cytoprotective properties. Both preclinical and clinical experiences show that the therapy with plas
Externí odkaz:
https://doaj.org/article/81338e3554414e0a80aaf3bb0be142c3
Autor:
Sabina Janciauskiene, Srinu Tumpara, Nils Helge Schebb, Falk F. R. Buettner, Malwina Mainka, Kokilavani Sivaraman, Stephan Immenschuh, Veronika Grau, Tobias Welte, Beata Olejnicka
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Human alpha-1-antitrypsin (AAT) encoded by the SERPINA1 gene, is an acute phase glycoprotein that regulates inflammatory responses via both protease inhibitory and non-inhibitory activities. We previously reported that AAT controls ATP-induced IL-1β
Externí odkaz:
https://doaj.org/article/3982131efe1046f8be0af6fdc1b06265
Autor:
Srinu Tumpara, Anna R. Gründing, Kokilavani Sivaraman, Sabine Wrenger, Beata Olejnicka, Tobias Welte, Maria J. Wurm, Paco Pino, Divor Kiseljak, Florian M. Wurm, Sabina Janciauskiene
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 15, p 7941 (2021)
For the treatment of severe COVID-19, supplementation with human plasma-purified α-1 antitrypsin (AAT) to patients is currently considered. AAT inhibits host proteases that facilitate viral entry and possesses broad anti-inflammatory and immunomodul
Externí odkaz:
https://doaj.org/article/381b24cc03dd491d94d7b6dacb501463
Autor:
Kokilavani Sivaraman, Sabine Wrenger, Bin Liu, Dirk Schaudien, Christina Hesse, Gema Gomez-Mariano, Sara Perez-Luz, Katherina Sewald, David DeLuca, Maria J Wurm, Paco Pino, Tobias Welte, Beatriz Martinez-Delgado, Sabina Janciauskiene
Publikováno v:
Journal of Leukocyte Biology. 113:58-70
Rodent models of lipopolysaccharide (LPS)–induced pulmonary inflammation are used for anti-inflammatory drug testing. We aimed to characterize mice responses to aerosolized LPS alone or with intraperitoneal (i.p.) delivery of alpha1-antitrypsin (AA
Autor:
Beata Olejnicka, Srinu Tumpara, Paco Pino, Kokilavani Sivaraman, Tobias Welte, Florian M. Wurm, Maria J Wurm, Anna R. Gründing, Sabine Wrenger, Sabina Janciauskiene, Divor Kiseljak
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 15
International Journal of Molecular Sciences, Vol 22, Iss 7941, p 7941 (2021)
Volume 22
Issue 15
International Journal of Molecular Sciences, Vol 22, Iss 7941, p 7941 (2021)
For the treatment of severe COVID-19, supplementation with human plasma-purified α-1 antitrypsin (AAT) to patients is currently considered. AAT inhibits host proteases that facilitate viral entry and possesses broad anti-inflammatory and immunomodul