Zobrazeno 1 - 10
of 213
pro vyhledávání: '"Kokichi, Sugano"'
Autor:
Nobuhiko Kanaya, Thijs A. vanSchaik, Hideki Aoki, Yumiko Sato, Fumitaka Taniguchi, Kunitoshi Shigeyasu, Kokichi Sugano, Kiwamu Akagi, Hideyuki Ishida, Kohji Tanakaya
Publikováno v:
Annals of Gastroenterological Surgery, Vol 8, Iss 6, Pp 1008-1016 (2024)
Abstract Aim Lynch syndrome (LS) is a dominantly inherited syndrome characterized by an increased risk for LS associated tumors such as colorectal cancer (CRC) and gastric cancer (GC). However, the clinical benefit of surveillance for GC remains uncl
Externí odkaz:
https://doaj.org/article/e1676b30cca14d9bbabe786e88822a90
Autor:
Tetsuji Takayama, Naoki Muguruma, Masahiro Igarashi, Shozo Ohsumi, Shiro Oka, Fumihiko Kakuta, Yoshiaki Kubo, Hideki Kumagai, Mika Sasaki, Tamotsu Sugai, Kokichi Sugano, Yuko Takeda, Hisashi Doyama, Kouji Banno, Suguru Fukahori, Yoichi Furukawa, Takahiro Horimatsu, Hideki Ishikawa, Takeo Iwama, Yasushi Okazaki, Yutaka Saito, Nariaki Matsuura, Michihiro Mutoh, Naohiro Tomita, Takashi Akiyama, Toshiki Yamamoto, Hideyuki Ishida, Yoshiko Nakayama
Publikováno v:
Journal of the Anus, Rectum and Colon, Vol 7, Iss 4, Pp 284-300 (2023)
Cowden syndrome (CS)/PTEN hamartoma tumor syndrome (PHTS) is a rare autosomal dominantly inherited condition caused by germline pathogenesis. It is associated with multiple hamartomatous lesions occurring in various organs and tissues, including the
Externí odkaz:
https://doaj.org/article/4255ab15b39b4693b801fad34a880813
Autor:
Satoyo Oda, Mineko Ushiama, Wataru Nakamura, Masahiro Gotoh, Noriko Tanabe, Tomoko Watanabe, Yoko Odaka, Kazuhiko Aoyagi, Hiromi Sakamoto, Takeshi Nakajima, Kokichi Sugano, Teruhiko Yoshida, Yuichi Shiraishi, Makoto Hirata
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Genetic testing of the APC gene by sequencing analysis and MLPA is available across commercial laboratories for the definitive genetic diagnosis of familial adenomatous polyposis (FAP). However, some genetic alterations are difficult to detect using
Externí odkaz:
https://doaj.org/article/16a379c2dd3e48d5a80a14093eefaf68
Autor:
Makoto Nakagawa, Eisuke Kobayashi, Masayoshi Yamada, Tomoko Watanabe, Makoto Hirata, Noriko Tanabe, Mineko Ushiama, Hiromi Sakamoto, Chiaki Sato, Taisuke Mori, Akihiko Yoshida, Teruhiko Yoshida, Kokichi Sugano, Akira Kawai
Publikováno v:
Hereditary Cancer in Clinical Practice, Vol 19, Iss 1, Pp 1-7 (2021)
Abstract Background Muir–Torre syndrome (MTS), which accounts for a small subset (1–3 %) of Lynch syndrome (LS), is an autosomal dominant genetic disorder characterized by sebaceous gland or keratoacanthoma associated with visceral malignancies.
Externí odkaz:
https://doaj.org/article/043b2434e9e943459da97a220dbdb95a
Autor:
Yasuto Yagi, Naoko Abeto, Junichi Shiraishi, Chieko Miyata, Satomi Inoue, Haruka Murakami, Moeko Nakashima, Kokichi Sugano, Mineko Ushiama, Teruhiko Yoshida, Kazuki Yamazawa
Publikováno v:
Human Genome Variation, Vol 9, Iss 1, Pp 1-3 (2022)
Abstract Hereditary leiomyomatosis and renal cell carcinoma caused by loss-of-function germline variants of the FH gene can develop into aggressive renal cell carcinoma (RCC). We report the case of a 27-year-old man who died of RCC. Genetic testing r
Externí odkaz:
https://doaj.org/article/947f9188f605479e991576af66b55a0e
Autor:
Daishi Naoi, Koji Koinuma, Hideki Sasanuma, Yasunaru Sakuma, Hisanaga Horie, Alan Kawarai Lefor, Kokichi Sugano, Mineko Ushiama, Teruhiko Yoshida, Naohiro Sata
Publikováno v:
Surgical Case Reports, Vol 7, Iss 1, Pp 1-6 (2021)
Abstract Background Familial adenomatous polyposis (FAP) is characterized by the presence of hundreds to thousands of colonic polyps, and extracolonic manifestations are likely to occur. Pancreatic tumors are rare extracolonic manifestations in patie
Externí odkaz:
https://doaj.org/article/089c127b5eb24bc39373118db6677733
Autor:
Masahiro Tomonari, Mariko Shimada, Yasuyuki Nakada, Izumi Yamamoto, Munenari Itoh, Yusuke Koike, Akimitsu Kobayashi, Jun Miki, Hiroki Yamada, Takahiro Kimura, Shinya Saito, Kokichi Sugano, Shigeki Sekine, Hiroyasu Yamamoto, Akihiko Asahina, Takashi Yokoo
Publikováno v:
BMC Nephrology, Vol 20, Iss 1, Pp 1-6 (2019)
Abstract Background Sebaceous carcinoma is a rare but progressive malignant skin cancer, and the incidence is approximately five times higher in post-transplant patients than in people who have not received kidney transplants. Sebaceous carcinoma is
Externí odkaz:
https://doaj.org/article/4080de3e9aba44cbb5f2f023276e7a89
Autor:
Tomoyuki Momma, Kenji Gonda, Yoshinori Akama, Eisei Endo, Daisuke Ujiie, Shotaro Fujita, Yuko Maejima, Shoichiro Horita, Kenju Shimomura, Shigehira Saji, Koji Kono, Rei Yashima, Fumiaki Watanabe, Kokichi Sugano, Tadashi Nomizu
Publikováno v:
BMC Medical Genetics, Vol 20, Iss 1, Pp 1-6 (2019)
Abstract Background Lynch syndrome, is an autosomal dominantly inherited disease that predisposes individuals to a high risk of colorectal cancers, and some mismatch-repair genes have been identified as causative genes. The purpose of this study was
Externí odkaz:
https://doaj.org/article/9be6b609b23e4de0a85235d579ea1bbe
Autor:
Yoshiaki Usui, Yukari Taniyama, Mikiko Endo, Yuriko N. Koyanagi, Yumiko Kasugai, Isao Oze, Hidemi Ito, Issei Imoto, Tsutomu Tanaka, Masahiro Tajika, Yasumasa Niwa, Yusuke Iwasaki, Tomomi Aoi, Nozomi Hakozaki, Sadaaki Takata, Kunihiko Suzuki, Chikashi Terao, Masanori Hatakeyama, Makoto Hirata, Kokichi Sugano, Teruhiko Yoshida, Yoichiro Kamatani, Hidewaki Nakagawa, Koichi Matsuda, Yoshinori Murakami, Amanda B. Spurdle, Keitaro Matsuo, Yukihide Momozawa
Publikováno v:
New England Journal of Medicine. 388:1181-1190
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b224be0546dfbcec1df2da781367cfe0
https://doi.org/10.1056/nejmoa2211807
https://doi.org/10.1056/nejmoa2211807
Autor:
Keijiro Mizukami, Yusuke Iwasaki, Eiryo Kawakami, Makoto Hirata, Yoichiro Kamatani, Koichi Matsuda, Mikiko Endo, Kokichi Sugano, Teruhiko Yoshida, Yoshinori Murakami, Hidewaki Nakagawa, Amanda B. Spurdle, Yukihide Momozawa
Publikováno v:
EBioMedicine, Vol 60, Iss , Pp 103033- (2020)
Background: National Comprehensive Cancer Network (NCCN) recently recommended germline genetic testing for all pancreatic cancer patients. However, the genes targeted by genetic testing and the feasibility of selecting patients likely to carry pathog
Externí odkaz:
https://doaj.org/article/6a8653e9cd964434b6a9a795a05beced