Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Koki MIMURA"'
Autor:
Koki Mimura, Jumpei Matsumoto, Daichi Mochihashi, Tomoaki Nakamura, Hisao Nishijo, Makoto Higuchi, Toshiyuki Hirabayashi, Takafumi Minamimoto
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Nonhuman primates (NHPs) exhibit complex and diverse behavior that typifies advanced cognitive function and social communication, but quantitative and systematical measure of this natural nonverbal processing has been a technical challenge.
Externí odkaz:
https://doaj.org/article/6093c6dd9364430580057493bfddded4
Autor:
Kei Oyama, Kei Majima, Yuji Nagai, Yukiko Hori, Toshiyuki Hirabayashi, Mark A. G. Eldridge, Koki Mimura, Naohisa Miyakawa, Atsushi Fujimoto, Yuki Hori, Haruhiko Iwaoki, Ken-ichi Inoue, Richard C. Saunders, Masahiko Takada, Noriaki Yahata, Makoto Higuchi, Barry J. Richmond, Takafumi Minamimoto
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Primates must adapt to changing environments by optimizing their behavior to make beneficial choices. At the core of adaptive behavior is the orbitofrontal cortex (OFC) of the brain, which updates choice value through direct experience or kn
Externí odkaz:
https://doaj.org/article/f27f8d73cd764fdea074b296a315d225
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Temporal discounting, in which the recipient of a reward perceives the value of that reward to decrease with delay in its receipt, is associated with impulsivity and psychiatric disorders such as depression. Here, we investigate the role of
Externí odkaz:
https://doaj.org/article/49c7bf42b78340898ae30e79830cdb12
Autor:
Toshiyuki Hirabayashi, Yuji Nagai, Yuki Hori, Yukiko Hori, Kei Oyama, Koki Mimura, Naohisa Miyakawa, Haruhiko Iwaoki, Ken-ichi Inoue, Tetsuya Suhara, Masahiko Takada, Makoto Higuchi, Takafumi Minamimoto
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Visual object memory is a fundamental element of various cognitive abilities, and the underlying neural mechanisms have been extensively examined especially in the anterior temporal cortex of primates. However, both macroscopic large-scale f
Externí odkaz:
https://doaj.org/article/02803be30c1241b9a4827729b6309ee6
Autor:
Yukiko Hori, Koki Mimura, Yuji Nagai, Yuki Hori, Katsushi Kumata, Ming-Rong Zhang, Tetsuya Suhara, Makoto Higuchi, Takafumi Minamimoto
Publikováno v:
PLoS Biology, Vol 22, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/12f6601302134a079b11829471a19d44
Autor:
Naohisa Miyakawa, Yuji Nagai, Yukiko Hori, Koki Mimura, Asumi Orihara, Kei Oyama, Takeshi Matsuo, Ken-ichi Inoue, Takafumi Suzuki, Toshiyuki Hirabayashi, Tetsuya Suhara, Masahiko Takada, Makoto Higuchi, Keisuke Kawasaki, Takafumi Minamimoto
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Pharmacological and surgical treatments of epilepsy can have unsatisfactory outcomes, so a more targeted and on-demand approach is desirable. Here, the authors demonstrate the usage of inhibitory chemogenetics in male nonhuman primates to attenuate t
Externí odkaz:
https://doaj.org/article/134aeee71b1746ecb0a7efa80a5b5681
Publikováno v:
Mechanical Engineering Journal, Vol 10, Iss 3, Pp 23-00076-23-00076 (2023)
Dump trucks are widely used in the construction industry. When sand is discharged from a dump truck bed, the friction with the bed causes sand to remain on the bed. Therefore, it is desirable to develop a technology to adhere low-friction fluororesin
Externí odkaz:
https://doaj.org/article/21c3b747c3c043e497c0214be5f0188e
Autor:
Koki Mimura, Yuji Nagai, Ken-ichi Inoue, Jumpei Matsumoto, Yukiko Hori, Chika Sato, Kei Kimura, Takashi Okauchi, Toshiyuki Hirabayashi, Hisao Nishijo, Noriaki Yahata, Masahiko Takada, Tetsuya Suhara, Makoto Higuchi, Takafumi Minamimoto
Publikováno v:
iScience, Vol 24, Iss 9, Pp 103066- (2021)
Summary: To interrogate particular neuronal pathways in nonhuman primates under natural and stress-free conditions, we applied designer receptors exclusively activated by designer drugs (DREADDs) technology to common marmosets. We injected adeno-asso
Externí odkaz:
https://doaj.org/article/dba7636b72e6406ab7a3138cb35b3dca
Autor:
Yukiko Hori, Yuji Nagai, Koki Mimura, Tetsuya Suhara, Makoto Higuchi, Sebastien Bouret, Takafumi Minamimoto
Publikováno v:
PLoS Biology, Vol 19, Iss 7, p e3001055 (2021)
It has been widely accepted that dopamine (DA) plays a major role in motivation, yet the specific contribution of DA signaling at D1-like receptor (D1R) and D2-like receptor (D2R) to cost-benefit trade-off remains unclear. Here, by combining pharmaco
Externí odkaz:
https://doaj.org/article/3753b596ec124f079a8928bc1f02d31c
Autor:
Yukiko Hori, Koki Mimura, Yuji Nagai, Atsushi Fujimoto, Kei Oyama, Erika Kikuchi, Ken-ichi Inoue, Masahiko Takada, Tetsuya Suhara, Barry J Richmond, Takafumi Minamimoto
Publikováno v:
eLife, Vol 10 (2021)
The term ‘temporal discounting’ describes both choice preferences and motivation for delayed rewards. Here we show that neuronal activity in the dorsal part of the primate caudate head (dCDh) signals the temporally discounted value needed to comp
Externí odkaz:
https://doaj.org/article/2f2885ca5ee249c1bbca5a95dad00965