Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Kok Siong Yeo"'
Autor:
Ke-En Tan, Wei Lun Ng, Georgi K. Marinov, Ken Hung-On Yu, Lu Ping Tan, Ee Shan Liau, Sook Yan Goh, Kok Siong Yeo, Kevin Y. Yip, Kwok-Wai Lo, Alan Soo-Beng Khoo, Lee-Fah Yap, Chee-Kwee Ea, Yat-Yuen Lim
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Epstein-Barr virus (EBV) has been recently found to generate novel circular RNAs (circRNAs) through backsplicing. However, comprehensive catalogs of EBV circRNAs in other cell lines and their functional characterization are still lacking. In
Externí odkaz:
https://doaj.org/article/6f280b89ec074aafa9b102c63d7b3441
Autor:
Cheng Zhang, Cristina Correia, Taylor M. Weiskittel, Shyang Hong Tan, Kevin Meng-Lin, Grace T. Yu, Jingwen Yao, Kok Siong Yeo, Shizhen Zhu, Choong Yong Ung, Hu Li
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Immune-related processes are important in underpinning the properties of clinical traits such as prognosis and drug response in cancer. The possibility to extract knowledge learned by artificial neural networks (ANNs) from omics data to explain cance
Externí odkaz:
https://doaj.org/article/14ff83bc322e41d5a10dea404feb7e91
Publikováno v:
Cells, Vol 10, Iss 3, p 580 (2021)
For nearly a decade, researchers in the field of pediatric oncology have been using zebrafish as a model for understanding the contributions of genetic alternations to the pathogenesis of neuroblastoma (NB), and exploring the molecular and cellular m
Externí odkaz:
https://doaj.org/article/ba482324170240b1ade99269d6573e50
Autor:
Ming Cheang Tan, Wan Ying Wong, Wei Lun Ng, Kok Siong Yeo, Taznim Begam Mohd Mohidin, Yat-Yuen Lim, Fadhil Lafta, Hapipah Mohd Ali, Chee-Kwee Ea
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170352 (2017)
Influenza virus is estimated to cause 3-5 million severe complications and about 250-500 thousand deaths per year. Different kinds of anti-influenza virus drugs have been developed. However, the emergence of drug resistant strains has presented a big
Externí odkaz:
https://doaj.org/article/fa32d32deb254960b5bff62570f23654
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e103915 (2014)
H3K9 methylation is one of the essential histone post-translational modifications for heterochromatin formation and transcriptional repression. Recently, several studies have demonstrated that H3K9 methylation negatively regulates the type I interfer
Externí odkaz:
https://doaj.org/article/4a5368d3610742ceab2a741c97a00fda
Autor:
Kevin Meng-Lin, Choong-Yong Ung, Cheng Zhang, Taylor M. Weiskittel, Philip Wisniewski, Zhuofei Zhang, Shyang-Hong Tan, Kok-Siong Yeo, Shizhen Zhu, Cristina Correia, Hu Li
Publikováno v:
Biomolecules; Volume 13; Issue 6; Pages: 895
Spatially resolved sequencing technologies help us dissect how cells are organized in space. Several available computational approaches focus on the identification of spatially variable genes (SVGs), genes whose expression patterns vary in space. The
Autor:
Shizhen Zhu, John M. Maris, Jennifer J. Westendorf, Hu Li, Jan M. van Deursen, A. Thomas Look, S. John Weroha, Komal S. Rathi, Gina L. Razidlo, Alexander Meves, Julia S. Lehman, Jorge Torres-Mora, Karen Fritchie, Ting Tao, Shuning He, Shuai Li, Janine H. van Ree, Xiaonan Hou, Cassie J. Howe, Zuag Paj Her, Taylor M. Levee, Choong Yong Ung, Jo Lynne Rokita, Erin N. Dankert Eggum, Cheng Zhang, Gonzalo Lopez, Kok Siong Yeo, Zhiwei Dong
SUPPLEMENTARY TABLES, FIGURES AND FIGURE LEGENDS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::438549837a6a26ad2aa79d8ab5c9d0bb
https://doi.org/10.1158/0008-5472.22429665
https://doi.org/10.1158/0008-5472.22429665
Autor:
Shizhen Zhu, John M. Maris, Jennifer J. Westendorf, Hu Li, Jan M. van Deursen, A. Thomas Look, S. John Weroha, Komal S. Rathi, Gina L. Razidlo, Alexander Meves, Julia S. Lehman, Jorge Torres-Mora, Karen Fritchie, Ting Tao, Shuning He, Shuai Li, Janine H. van Ree, Xiaonan Hou, Cassie J. Howe, Zuag Paj Her, Taylor M. Levee, Choong Yong Ung, Jo Lynne Rokita, Erin N. Dankert Eggum, Cheng Zhang, Gonzalo Lopez, Kok Siong Yeo, Zhiwei Dong
One of the greatest barriers to curative treatment of neuroblastoma is its frequent metastatic outgrowth prior to diagnosis, especially in cases driven by amplification of the MYCN oncogene. However, only a limited number of regulatory proteins that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3daaf20c598ffebd4594a52ff7e6e62
https://doi.org/10.1158/0008-5472.c.6513432.v1
https://doi.org/10.1158/0008-5472.c.6513432.v1
Autor:
Choong Y, Ung, Taylor M, Levee, Cheng, Zhang, Cristina, Correia, Kok-Siong, Yeo, Hu, Li, Shizhen, Zhu
Publikováno v:
Computational and Structural Biotechnology Journal. 20:3291-3303
Neuroblastoma (NB) is the most common extracranial solid tumor in children. Although only a few recurrent somatic mutations have been identified, chromosomal abnormalities, including the loss of heterozygosity (LOH) at the chromosome 1p and gains of
Autor:
Hu Li, Cheng Zhang, Gina L. Razidlo, Shuning He, Xiaonan Hou, Jo Lynne Rokita, Choong Yong Ung, Zhi-Wei Dong, Cassie J. Howe, Taylor M. Levee, S. John Weroha, Zuag Paj Her, Jennifer J. Westendorf, Janine H. van Ree, Julia S. Lehman, Kok Siong Yeo, John M. Maris, Alexander Meves, Erin N. Dankert Eggum, Shuai Li, Gonzalo Lopez, Shizhen Zhu, Jan M. van Deursen, Ting Tao, Jorge Torres-Mora, A. Thomas Look, Komal S. Rathi, Karen J. Fritchie
Publikováno v:
Cancer Research. 81:2995-3007
One of the greatest barriers to curative treatment of neuroblastoma is its frequent metastatic outgrowth prior to diagnosis, especially in cases driven by amplification of the MYCN oncogene. However, only a limited number of regulatory proteins that